Navigation Links
NREL finds a new cellulose digestion mechanism by a fast-eating enzyme
Date:1/7/2014

y catalytic domains working in concert most likely makes it such a good cellulose degrader."

Most commercial operations use enzyme cocktails, a combination of 15 to 20 different enzymes, to turn plant material into the sugars that are valuable to the biofuels industry. In most such cocktails, one type of enzyme, Cel7A, does the largest amount of work.

When researchers compared CelA to Cel7A, they discovered that at its optimal temperature of 50 degrees Celsius (122 degrees F), Cel7A achieves only 50% of the performance of CelA when converting Avicel.

CelA was discovered 15 years ago, but until this recent work, all that was known about this complex protein was its general architecture and that it had the ability to degrade cellulose.

This organism, initially grown on biomass by scientists from the University of Georgia, was used to produce extracellular enzymes (enzymes that function outside of the cell). Those extracellular enzymes later were purified and characterized at NREL using techniques including performance assays, advanced imaging, X-ray crystallography, and modeling on supercomputers.

NREL scientists found that CelA is not only very active on cellulose, but also attacks xylose. That could mean that levels of enzymes that specialize in removing xylose in commercial cocktails could be lowered, translating to lower costs.

If an enzyme can produce sugars more efficiently, it means lower cost for the enzyme cocktail, which is a major cost driver in the process of converting biomass into fuel.

The findings have important implications for industry, but also were fascinating for the scientists. "We are learning a lot about the evolution of these cellulases, how they can thrive in extreme environments, and how they operate on biomass," NREL scientist and the paper's lead author, Roman Brunecky, said.

"This discovery could reshape the landscape of commercial cellulase cocktail design," said Pau
'/>"/>

Contact: David Glickson
david.glickson@nrel.gov
303-275-4097
DOE/National Renewable Energy Laboratory
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. MIT research: Study finds room to store CO2 underground
2. Study finds circle hooks lower catch rate for offshore anglers
3. LSUHSC research finds HPV-related head & neck cancers rising, highest in middle-aged white men
4. Head and body lice appear to be the same species, genetic study finds
5. Study finds peoples niceness may reside in their genes
6. Large international study finds memory in adults impacted by versions of 4 genes
7. Improved loblolly pines better for the environment, study finds
8. NIST/UMass study finds evidence nanoparticles may increase plant DNA damage
9. As deadly cat disease spreads nationally, MU veterinarian finds effective treatment
10. Study finds cancer-fighting goodness in cholesterol
11. Study finds soda consumption increases overall stroke risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2015)... Mar. 24, 2015 Research and Markets ( http://www.researchandmarkets.com/research/kvdtcw/face_and_voice ... Biometrics - Global Strategic Business Report" report to their offering. ... Voice Biometrics in US$ Thousands by the following Segments: Face Biometrics, ... US, Canada , Japan , ... Middle East & Africa , ...
(Date:3/23/2015)... 23, 2015   HOYOS Labs , a leading ... announced that the Company will demonstrate multiple biometrics-based technologies ... consumers at Connect:ID on March 23 through 25, 2015, ... will highlight the IEEE Biometric Open Protocol Standard; free ... enterprise access control system. BOPS was invented by HOYOS ...
(Date:3/20/2015)... 19, 2015 Research and Markets ( http://www.researchandmarkets.com/research/rswjb4/hand_geometry ... - Global Strategic Business Report" report to their offering. ... Geometry in US$ Thousands. The report provides separate comprehensive analytics ... Japan , Europe , ... Rest of World. Annual estimates and forecasts are ...
Breaking Biology News(10 mins):Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 2Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 3Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 4Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 5Face and Voice Biometrics - Global Strategic Business Report 2015: Face Recognition Gains Prominence in Immigration Control 6HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 2Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 4
... could one day tend their own crops on long ... healthy candidate to help satisfy a sweet tooth - ... Cary Mitchell, professor of horticulture, and Gioia Massa, ... and found one variety, named Seascape, which seems to ...
... and other plants help keep the planet cool, but rising ... this global air conditioner. According to a new study by ... more than a quarter of the warming from increased carbon ... warming is in addition to carbon dioxide,s better-known effect as ...
... Academy of Natural Sciences today announced it will give ... who has done more than anyone to document one ... Dr. Daniel Otte, arguably the world,s authority on grasshoppers ... prestigious Joseph Leidy Award for scientific excellence on Thursday, ...
Cached Biology News:Low-maintenance strawberry may be good crop to grow in space 2CO2 effects on plants increases global warming 2CO2 effects on plants increases global warming 3Noted entomologist to receive science excellence award 2Noted entomologist to receive science excellence award 3
(Date:3/27/2015)... Earlier this year, the Capillus272Pro™ ... regrowth in adult men and women with androgenic alopecia ... classifications of IIa-V and Fitzpatrick Classification of Skin phototypes ... that over-promise and under-deliver, FDA Clearance underscores the safety ... among more than 80 million men and women who ...
(Date:3/27/2015)... The consumption of compound fertilizers (NPK) ... and high prices in 2008. However, the situation has ... on gaining momentum now. , To date, the world ... 100,000 thousand tonnes. No considerable growth was registered in ... rocketed during 2012-2013, registering 11% growth as against the ...
(Date:3/27/2015)... , 27. März 2015  Peter ... in Biomedical Science für seine bahnbrechende Arbeit ... zwischen Zellkompartimenten transportiert werden, sowie für die ... zur Reaktion auf Stress nutzen, der mit ... Walter ist Professor für Biochemie an der ...
(Date:3/27/2015)... LANSING, Mich. , March 27, 2015  Neogen ... Properties, LLC, has adopted a prearranged trading plan in ... James Herbert , Chairman and CEO of Neogen Corporation, ... shares of Neogen Corporation common stock. Herbert ... the disclosure was appropriate. The filing is only for ...
Breaking Biology Technology:Dr. Robert Leonard Applauds FDA Clearance of Capillus272Pro™ Hair Loss Laser Cap 2World NPK Fertilizers Market Keeps On Gaining Momentum, According to BAC Reports Study Available at MarketPublishers.com 2World NPK Fertilizers Market Keeps On Gaining Momentum, According to BAC Reports Study Available at MarketPublishers.com 3Deutschstämmiger Zellbiologe Peter Walter gewinnt den Vilcek Prize in Biomedical Science 2015 2Deutschstämmiger Zellbiologe Peter Walter gewinnt den Vilcek Prize in Biomedical Science 2015 3Deutschstämmiger Zellbiologe Peter Walter gewinnt den Vilcek Prize in Biomedical Science 2015 4Neogen CEO adopts 10b5-1 Trading Plan 2
... 24 Sigma-Aldrich Corporation (Nasdaq: SIAL ) will be presenting at ... in London, 7:45 AM US/CST. Interested parties may listen via live audio ... tor.sig m a a ldrich.com/ . ... , About Sigma-Aldrich: Sigma-Aldrich is a leading Life ...
... , SHANGHAI, ... Patent & Trademark Office (PTO) has allowed the patent ... NOD technology is a highly ... to enable oral delivery of drugs,otherwise administered as injections. ...
... , , SEATTLE, Nov. 24 ... and the Odessa Public Development Authority (OPDA) were recently ... Board (CERB) in a private/public partnership to construct the ... , "This investment will significantly speed the ...
Cached Biology Technology:Blue Marble Energy, OPDA Awarded $2M by WA's Community Economic Revitalization Board 2
Human interferon-beta (IFN-beta). Recognizes amino acids 30-47 of IFN-beta. No cross-reactivity with Human IFN-alpha or IFN-gamma....
Rat Hepatocytes (RH) (>3,000,000 cells)...
... the detection of very small amounts of ... with improved resolution (20,000) and mass accuracy ... in protein identification. The AXIMA-CFRplus also includes ... target handling and the ability to analyse ...
...
Biology Products: