Navigation Links
NREL finds a new cellulose digestion mechanism by a fast-eating enzyme
Date:1/7/2014

y catalytic domains working in concert most likely makes it such a good cellulose degrader."

Most commercial operations use enzyme cocktails, a combination of 15 to 20 different enzymes, to turn plant material into the sugars that are valuable to the biofuels industry. In most such cocktails, one type of enzyme, Cel7A, does the largest amount of work.

When researchers compared CelA to Cel7A, they discovered that at its optimal temperature of 50 degrees Celsius (122 degrees F), Cel7A achieves only 50% of the performance of CelA when converting Avicel.

CelA was discovered 15 years ago, but until this recent work, all that was known about this complex protein was its general architecture and that it had the ability to degrade cellulose.

This organism, initially grown on biomass by scientists from the University of Georgia, was used to produce extracellular enzymes (enzymes that function outside of the cell). Those extracellular enzymes later were purified and characterized at NREL using techniques including performance assays, advanced imaging, X-ray crystallography, and modeling on supercomputers.

NREL scientists found that CelA is not only very active on cellulose, but also attacks xylose. That could mean that levels of enzymes that specialize in removing xylose in commercial cocktails could be lowered, translating to lower costs.

If an enzyme can produce sugars more efficiently, it means lower cost for the enzyme cocktail, which is a major cost driver in the process of converting biomass into fuel.

The findings have important implications for industry, but also were fascinating for the scientists. "We are learning a lot about the evolution of these cellulases, how they can thrive in extreme environments, and how they operate on biomass," NREL scientist and the paper's lead author, Roman Brunecky, said.

"This discovery could reshape the landscape of commercial cellulase cocktail design," said Pau
'/>"/>

Contact: David Glickson
david.glickson@nrel.gov
303-275-4097
DOE/National Renewable Energy Laboratory
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. MIT research: Study finds room to store CO2 underground
2. Study finds circle hooks lower catch rate for offshore anglers
3. LSUHSC research finds HPV-related head & neck cancers rising, highest in middle-aged white men
4. Head and body lice appear to be the same species, genetic study finds
5. Study finds peoples niceness may reside in their genes
6. Large international study finds memory in adults impacted by versions of 4 genes
7. Improved loblolly pines better for the environment, study finds
8. NIST/UMass study finds evidence nanoparticles may increase plant DNA damage
9. As deadly cat disease spreads nationally, MU veterinarian finds effective treatment
10. Study finds cancer-fighting goodness in cholesterol
11. Study finds soda consumption increases overall stroke risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... de 2015 BGI llevará a cabo la 10ª ... al 25 de octubre de 2015, en ... su décimo aniversario este año. Desde su inauguración en ... reuniones anuales más influyentes del mundo en los campos ... científicas más dinámicas, entusiastas y amenas. ICG-10 ...
(Date:7/31/2015)... La 10 th International Conference on Genomics ... 22 al 25 de octubre de 2015 en ... conferencia celebra su décimo aniversario. Desde su inauguración en el ... reuniones anuales más influyentes del mundo en el campo ,ómico, ... y mejores a nivel científico. ICG-10 se ...
(Date:7/31/2015)... SHENZHEN, China , July 31, 2015 The ... ) will be held by BGI from October 22-25, 2015, in ... The conference is celebrating its 10 th ... become one of the world,s most influential annual meetings in ... enthusiastic, and enjoyable scientific gatherings. ICG-10 focuses ...
Breaking Biology News(10 mins):La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 2La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 3La 10th International Conference on Genomics (ICG-10) se llevará a cabo en octubre 2La 10th International Conference on Genomics (ICG-10) se llevará a cabo en octubre 3The 10th International Conference on Genomics (ICG-10) to Open in October 2
... misleading: In most forests, the amount of carbon held in ... trees themselves. If you,re a land manager trying to ... climate change by soaking up atmospheric carbon and storing it, ... while scientists can precisely measure and predict the amount of ...
... Listed below are the selected highlights for the April ... Genetics . The April issue is available online at ... 193, April 2013, Copyright 2013. Please feel free ... articles on a wide array of topics including methods, technology ...
... known for promoting erections, it may also serve as a weight ... fat" relative to unhealthy "white fat" than it would otherwise do ... The FASEB Journal , this is because sildenafil ... as a messenger molecule used by the body to control blood ...
Cached Biology News:Soils in newly forested areas store substantial carbon that could help offset climate change 2Genetics Society of America's Genetics journal highlights for April 2013 2Genetics Society of America's Genetics journal highlights for April 2013 3Genetics Society of America's Genetics journal highlights for April 2013 4Drug for erectile disorder show promise in the treatment of obesity 2
(Date:7/29/2015)... According to a new market research report, ... , published by Mordor Intelligence, the Global market is expected ... 2020, with North America being the ... global market size. The Global market for Stem Cells is ... period of (2015-2020).      (Logo: http://photos.prnewswire.com/prnh/20150428/740799) , ...
(Date:7/29/2015)... July 29, 2015  HealthSouth Corporation (NYSE: ... providers of post-acute healthcare services, offering both facility-based ... of operations for the second quarter ended June 30, ... characterized by strong volume growth in both segments ... said Jay Grinney, President and Chief Executive Officer ...
(Date:7/29/2015)... ... July 29, 2015 , ... Brady ... GHS Label Guide . To align chemical container labeling with OSHA’s updated ... explanations of label components, an example of an accurate label, and pictogram uses ...
(Date:7/29/2015)...  Indivior PLC (LON: INDV) today announced that the ... accepted and received Priority Review by the U.S. Food ... overdose. This naloxone nasal spray comes as a pre-filled ... into the nasal mucosa. 1 The device has ... be better equipped to help an opioid overdose victim. ...
Breaking Biology Technology:Asia Pacific to Dominate the Global Stem Cell Market - Vericel Corporation, Ocata Therpeutics, Athersys Inc., Cryo-Cell International, Geron Corporation, StemCells, Inc. Among the Major Players 2Asia Pacific to Dominate the Global Stem Cell Market - Vericel Corporation, Ocata Therpeutics, Athersys Inc., Cryo-Cell International, Geron Corporation, StemCells, Inc. Among the Major Players 3HealthSouth Reports Results for Second Quarter 2015 2HealthSouth Reports Results for Second Quarter 2015 3HealthSouth Reports Results for Second Quarter 2015 4HealthSouth Reports Results for Second Quarter 2015 5HealthSouth Reports Results for Second Quarter 2015 6HealthSouth Reports Results for Second Quarter 2015 7HealthSouth Reports Results for Second Quarter 2015 8HealthSouth Reports Results for Second Quarter 2015 9HealthSouth Reports Results for Second Quarter 2015 10HealthSouth Reports Results for Second Quarter 2015 11HealthSouth Reports Results for Second Quarter 2015 12HealthSouth Reports Results for Second Quarter 2015 13HealthSouth Reports Results for Second Quarter 2015 14HealthSouth Reports Results for Second Quarter 2015 15HealthSouth Reports Results for Second Quarter 2015 16HealthSouth Reports Results for Second Quarter 2015 17HealthSouth Reports Results for Second Quarter 2015 18HealthSouth Reports Results for Second Quarter 2015 19HealthSouth Reports Results for Second Quarter 2015 20HealthSouth Reports Results for Second Quarter 2015 21HealthSouth Reports Results for Second Quarter 2015 22HealthSouth Reports Results for Second Quarter 2015 23HealthSouth Reports Results for Second Quarter 2015 24HealthSouth Reports Results for Second Quarter 2015 25HealthSouth Reports Results for Second Quarter 2015 26HealthSouth Reports Results for Second Quarter 2015 27HealthSouth Reports Results for Second Quarter 2015 28HealthSouth Reports Results for Second Quarter 2015 29HealthSouth Reports Results for Second Quarter 2015 30HealthSouth Reports Results for Second Quarter 2015 31HealthSouth Reports Results for Second Quarter 2015 32HealthSouth Reports Results for Second Quarter 2015 33HealthSouth Reports Results for Second Quarter 2015 34
... TauTaTis, Inc. announces that its lead compound for inhibition ... Alzheimer,s Disease, has been recognized as the most potent ... LRRK2 reported to date. Mutations of this gene ... most genetic frequent cause of Parkinson,s Disease.TauTaTis, lead compound ...
... the world,s first omega-3 enhanced water is available ... Zymes Omega Solutions, Inc., an affiliate of ... of the world,s first omega-3 enhanced water, ... new water uses Zymes, PTS technology to solubilize ...
... Innovative Company Makes it Possible for Employers to Hire ... March 16 Today,s outsourcing industry has taken a ... by Cybracero Systems ( http://www.cybracero.com ), which ... work remotely in the first-world countries without ever having ...
Cached Biology Technology:TauTaTis Discovers Potent Inhibitor of Parkinson's Disease Gene Activity 2Zymes Omega Solutions Bottles and Launches the World's First Omega-3 Enhanced Water 2New Technology to Revolutionize the Way the Planet Does Business 2
... Plating Beads Sterile plating in just ... rods and potentially hazardous ethanol flaming, More ... of ready-to-use sterile packaging: dispenser bottle for spreading ... Fastest and easiest way to spread ...
... a regulated environment, Pipette Tracker Pro ... that automates gravimetric pipette calibration and ... meets todays regulatory compliance requirements. Pipette ... that includes a full security implementation, ...
... (RTL) can provide you with the ... method development and validation ,Performance of ... of your GMP manufacturing environment ,Assurance ... a full spectrum of microbiological services ...
... IgY) , After we receive your antigen (see ... appropriate number of chickens and begin to collect ... (usually over a period of 3-5 days), we ... of four injections into the breast muscle. The ...
Biology Products: