Navigation Links
NIST technique controls sizes of nanoparticle clusters for EHS studies
Date:2/2/2011

The same properties that make engineered nanoparticles attractive for numerous applicationssmall as a virus, biologically and environmentally stabile, and water-solublealso cause concern about their long-term impacts on environmental health and safety (EHS). One particular characteristic, the tendency for nanoparticles to clump together in solution, is of great interest because the size of these clusters may be key to whether or not they are toxic to human cells. Researchers at the National Institute of Standards and Technology (NIST) have demonstrated for the first time a method for producing nanoparticle clusters in a variety of controlled sizes that are stable over time so that their effects on cells can be studied properly.*

In their tests, the NIST team made samples of gold, silver, cerium oxide and positively-charged polystyrene nanoparticles and suspended them separately in cell culture medium, allowing clumping to occur in each. They stopped the clumping by adding a protein, bovine serum albumin (BSA), to the mixtures. The longer the nanoparticles were allowed to clump together, the larger the size of the resulting cluster. For example, a range of clustering times using 23 nanometer silver nanoparticles produced a distribution of masses between 43 and 1,400 nanometers in diameter. Similar size distributions for the other three nanoparticle types were produced using this method.

The researchers learned that using the same "freezing times"the points at which BSA was added to halt the processyielded consistent size distributions for all four nanoparticle types. Additionally, all of the BSA-controlled dispersions remained stable for 2-3 days, which is sufficient for many toxicity studies.

Having successfully shown that they could control the production of nanoparticle clumps of different sizes, the researchers wanted next to prove that their creations could be put to work. Different-sized silver nanoparticle clusters were mixe
'/>"/>

Contact: Michael E. Newman
michael.newman@nist.gov
301-975-3025
National Institute of Standards and Technology (NIST)
Source:Eurekalert  

Page: 1 2

Related biology news :

1. New technique to see neurons of the deep brain for months at a time developed at Stanford
2. Technique allows researchers to identify key maize genes for increased yield
3. GEN co-sponsors roundtable discussion on novel bioremediation techniques
4. Quartz crystal microbalances enable new microscale analytic technique
5. New imaging technique accurately finds cancer cells, fast
6. New oyster farming technique increases productivity, offers entrepreneurial opportunities
7. Invention helps students learn surgical techniques before operating on patients
8. Radically simple technique developed to grow conducting polymer thin films
9. Optical technique reveals unnexpected complexity in mammalian olfactory coding
10. Technique to reattach teeth using stem cells developed at UIC
11. New oil detection technique
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
NIST technique controls sizes of nanoparticle clusters for EHS studies
(Date:9/18/2014)... deep in the primitive brainstem has revealed how we ... School of Medicine and the University at Buffalo School ... second "sleep node" identified in the mammalian brain whose ... produce deep sleep. , Published online in August in ... half of all of the brain,s sleep-promoting activity originates ...
(Date:9/18/2014)... research into the Crimean-Congo hemorrhagic fever virus (CCHFV), a ... humans similar to that caused by Ebolavirus, has identified ... has the potential to lead to novel targets for ... research, reported in a paper published today in the ... at the Texas Biomedical Research Institute and their colleagues, ...
(Date:9/18/2014)... and the Quebec government have discovered microplastics (in ... of Fisheries and Aquatic Sciences . , The ... industrial cleansers, to which they are commonly added ... buoyancy, they may readily pass through sewage treatment ... the world,s oceans, but have only recently been ...
Breaking Biology News(10 mins):No sedative necessary: Scientists discover new 'sleep node' in the brain 2Research milestone in CCHF virus could help identify new treatments 2Microplastic pollution discovered in St. Lawrence River sediments 2
... have fish-like sensations, advanced ship design and more, four ... on Dec. 23 learned they will receive the nation,s ... researchers have been selected for Presidential Early Career Awards ... at a ceremony at the White House early this ...
... forces in a quest to correct a faulty chromosome through ... , used stem cells to correct a defective "ring chromosome" ... correct chromosome abnormalities that give rise to birth defects, mental ... may be possible to use this approach to take cells ...
... a key difference in the biological mechanisms by which the ... study, published in the journal Nature Immunology and ... Life Sciences, centred on STAT1, a protein that can bind ... in the body. STAT-1 responds to interferon signals, hormone-like ...
Cached Biology News:White House lauds ONR-funded researchers for early success 2Nature study discovers chromosome therapy to correct a severe chromosome defect 2Nature study discovers chromosome therapy to correct a severe chromosome defect 3Research uncovers key difference between our bodies' fight against viruses and bacteria 2
(Date:9/18/2014)... , Sept. 18, 2014  Health Enhancement Products, Inc. ... investigating early-stage algae bioactive compounds and metabolic processes, is pleased ... company,s board of directors. Ms. Nola E. Masterson , ... advisor joined the board effective September 17, 2014. ... agree to join our board," states Andrew Dahl , ...
(Date:9/18/2014)... 2014 On Tuesday, Secretary of Energy ... Risch for National Lab Day on the Hill. The ... national laboratory system. Durbin and Risch also formally launched ... awareness of the reach of the national labs as ... address some of our nation's most pressing challenges. , ...
(Date:9/18/2014)... -- Research and Markets has announced the ... 2014" report to their offering. ... professional and in-depth study on the current state of ... provides a basic overview of the industry including definitions, ... market analysis is provided for the international markets including ...
(Date:9/18/2014)... 2014  U.S. biotech company Kultevat has ... for technology developed by the Donald Danforth Plant ... including for applications in production of natural rubber in ... was developed under the direction of Roger Beachy ... president of the Danforth Plant Science Center, and is ...
Breaking Biology Technology:Health Enhancement Announces New Board Member In Advance Of Annual Shareholder Meeting 2Lab Day Highlight Labs' Contribution to U.S. Competitiveness and Innovation 2Lab Day Highlight Labs' Contribution to U.S. Competitiveness and Innovation 3Global Human Albumin Industry Report 2014 2Global Human Albumin Industry Report 2014 3Kultevat obtains license of gene switch technology 2
... magnetic fields and tiny iron-bearing particles to drive healthy ... done in animals, may lead to a new method ... diseased organs in people. , The study team, led ... Chair of Pediatric Cardiology at The Childrens Hospital of ...
... BALTIMORE, Jan. 7 Physicians and ... California will benefit from,a new partnership ... University,Medical Center, providing resources to help ... thereby improving patient care., (Logo: ...
... 7 Cephalon, Inc. (Nasdaq:,CEPH) announced today that the ... the JPMorgan Healthcare Conference are now available on the,"Investor ... On Tuesday, January 8, 2008, Frank Baldino, Jr.,Ph.D., Chairman ... the,Conference beginning at 2:00 p.m. Pacific Time (5 p.m. ...
Cached Biology Technology:Researchers use magnetism to target cells to animal arteries 2Researchers use magnetism to target cells to animal arteries 3Physicians Practice, Loma Linda Partner to Improve Patient Care in Southern California 2Cephalon Presentation Slides for the 26th Annual JPMorgan Healthcare Conference Now Available 2
Mouse monoclonal antibody raised against a partial recombinant FBXO11. NCBI Entrez Gene ID = FBXO11...
Mouse polyclonal antibody raised against a partial recombinant LASS3. NCBI Entrez Gene ID = 204219...
... Antibody against Nonmuscle Myosin II Heavy ... (Stored in TBS + 0.03% Thimerosal) ... peptide SDVNETQPPQSE corresponding to the C-terminus ... B (MHC-B) This antibody is effective ...
... Anti-Mi-2 Immunogen : ... acid residues 474-970 of human ... 7.4, 0.105M NaCl, 0.035% sodium ... Assurance: routinely evaluated by immunoblot ...
Biology Products: