Navigation Links
NIST issues human milk and blood serum SRMs for contaminant measurements

Responding to scientists' need to measure organic contaminants in human body fluids, the National Institute of Standards and Technology (NIST) has recently made four new Standard Reference Materials (SRMs) available for purchase. Developed in collaboration with the Centers for Disease Control and Prevention (CDC), the human milk and serum SRMs have certified levels of contaminants, including flame retardants and pesticides, commonly found in the U.S. population. Scientists at the CDC and other laboratories will use the SRMs as controls in their experiments to ensure their methods are providing trustworthy results.

NIST first released its first serum-based SRM (SRM 1589 Polychlorinated Biphenyls in Human Serum) in 1985 to aid with the detection of polychlorinated biphenyls (PCBs), a toxic mixture of compounds used in transformer oils that was banned in the U.S. in the 1970s. Since NIST researchers last updated the SRM in 2000, the levels of PCBs, pesticides, dioxins/furans and other contaminants have decreased by 50 percent while the levels of brominated flame retardants, chemicals found in carpeting and upholstery, have been on the rise. NIST researchers created the new SRMs to reflect these changes.

The first of their kind, the milk SRMs contain similar contaminants as the serum materials.

To prepare these SRMs, scientists collected 200 liters of blood serum and 100 liters of milk from banks across the United States and divided the sample pools in half. (Note that the milk that was used to prepare the SRM was not suitable for feeding babies because the donors may have taken medications such as acetaminophen or the milk had reached its expiration date.) Researchers packaged half of each material as received, containing the natural (unfortified) level of contaminants, and treated (fortified) the other halves with a solution containing 172 selected contaminants. The fortified samples contain a concentration of those contaminants at levels five to 10 times higher than the median concentrations found in the U.S. population.

NIST SRMs have been rigorously tested and certified as having specific properties that researchers can trust as accurate within stated levels of uncertainty. The values stated on the certificates for these SRMs were measured by NIST and the CDC using a number of different methods including gas and liquid chromatography with mass spectrometry detection.


Contact: Mark Esser
National Institute of Standards and Technology (NIST)

Related biology news :

1. Chloroplast f and m Thioredoxins Discovered in Nonphotosynthetic Tissues
2. 200 journals join in theme issues on poverty and human development
3. Knocking out cell receptor may help block fat deposits in tissues, prevent weight gain
4. Media highlights in the November issues of Biophysical Journal
5. Media highlights in the January issues of Biophysical Journal
6. NAS to hold 2-day summit on energy issues
7. NHLBI issues first US von Willebrand Disease clinical practice guidelines
8. At ACS national meeting, global initiative set to tackle water issues
9. Expanded histology methods book covers processing of animal, plant, and microbial tissues
10. Experts tackle shipment issues for beneficial radiation sources
11. Origin of cells for connective tissues of skull and face challenged
Post Your Comments:
Related Image:
NIST issues human milk and blood serum SRMs for contaminant measurements
(Date:11/11/2015)... , Nov. 11, 2015   MedNet Solutions , an ... of clinical research, is pleased to announce that it will ... Trials (PCT) event, to be held November 17-19 in ... to view live demonstrations of iMedNet , ... how iMedNet has been able to deliver time ...
(Date:11/10/2015)... , Nov. 10, 2015 ... behavioral biometrics that helps to identify and verify ... Signature is considered as the secure and accurate ... identification of a particular individual because each individual,s ... accurate results especially when dynamic signature of an ...
(Date:11/9/2015)... , Nov. 9, 2015  Synaptics Inc. (NASDAQ: ... solutions, today announced broader entry into the automotive market ... that match the pace of consumer electronics human interface ... sensors are ideal for the automotive industry and will ... Europe , Japan ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... 24, 2015  Asia-Pacific (APAC) holds the third-largest ... market. The trend of outsourcing to low-cost locations ... higher volume share for the region in the ... margins in the CRO industry will improve. ... ( ), finds that the market earned ...
(Date:11/24/2015)... , Nov. 24, 2015 /CNW/ - iCo Therapeutics ("iCo" ... reported financial results for the quarter ended September ... in Canadian dollars and presented under International Financial ... States ," said Andrew Rae , ... regarding iCo-008 are not only value enriching for ...
(Date:11/24/2015)... -- Clintrax Global, Inc., a worldwide provider of clinical research services headquartered ... the company has set a new quarterly earnings record in Q3 ... posted for Q3 of 2014 to Q3 of 2015.   ... , with the establishment of an Asia-Pacific ... United Kingdom and Mexico , with ...
(Date:11/24/2015)... SHPG ) announced today that Jeff Poulton , Chief ... Annual Healthcare Conference in New York City , ... p.m. GMT). --> SHPG ) announced today that ... Jaffray 27 th Annual Healthcare Conference in New ... 8:30 a.m. EST (1:30 p.m. GMT). --> Shire plc ...
Breaking Biology Technology: