Navigation Links
NIST issues human milk and blood serum SRMs for contaminant measurements
Date:7/1/2009

Responding to scientists' need to measure organic contaminants in human body fluids, the National Institute of Standards and Technology (NIST) has recently made four new Standard Reference Materials (SRMs) available for purchase. Developed in collaboration with the Centers for Disease Control and Prevention (CDC), the human milk and serum SRMs have certified levels of contaminants, including flame retardants and pesticides, commonly found in the U.S. population. Scientists at the CDC and other laboratories will use the SRMs as controls in their experiments to ensure their methods are providing trustworthy results.

NIST first released its first serum-based SRM (SRM 1589 Polychlorinated Biphenyls in Human Serum) in 1985 to aid with the detection of polychlorinated biphenyls (PCBs), a toxic mixture of compounds used in transformer oils that was banned in the U.S. in the 1970s. Since NIST researchers last updated the SRM in 2000, the levels of PCBs, pesticides, dioxins/furans and other contaminants have decreased by 50 percent while the levels of brominated flame retardants, chemicals found in carpeting and upholstery, have been on the rise. NIST researchers created the new SRMs to reflect these changes.

The first of their kind, the milk SRMs contain similar contaminants as the serum materials.

To prepare these SRMs, scientists collected 200 liters of blood serum and 100 liters of milk from banks across the United States and divided the sample pools in half. (Note that the milk that was used to prepare the SRM was not suitable for feeding babies because the donors may have taken medications such as acetaminophen or the milk had reached its expiration date.) Researchers packaged half of each material as received, containing the natural (unfortified) level of contaminants, and treated (fortified) the other halves with a solution containing 172 selected contaminants. The fortified samples contain a concentration of those contaminants at levels five to 10 times higher than the median concentrations found in the U.S. population.

NIST SRMs have been rigorously tested and certified as having specific properties that researchers can trust as accurate within stated levels of uncertainty. The values stated on the certificates for these SRMs were measured by NIST and the CDC using a number of different methods including gas and liquid chromatography with mass spectrometry detection.


'/>"/>

Contact: Mark Esser
mark.esser@nist.gov
301-975-8735
National Institute of Standards and Technology (NIST)
Source:Eurekalert  

Related biology news :

1. Chloroplast f and m Thioredoxins Discovered in Nonphotosynthetic Tissues
2. 200 journals join in theme issues on poverty and human development
3. Knocking out cell receptor may help block fat deposits in tissues, prevent weight gain
4. Media highlights in the November issues of Biophysical Journal
5. Media highlights in the January issues of Biophysical Journal
6. NAS to hold 2-day summit on energy issues
7. NHLBI issues first US von Willebrand Disease clinical practice guidelines
8. At ACS national meeting, global initiative set to tackle water issues
9. Expanded histology methods book covers processing of animal, plant, and microbial tissues
10. Experts tackle shipment issues for beneficial radiation sources
11. Origin of cells for connective tissues of skull and face challenged
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
NIST issues human milk and blood serum SRMs for contaminant measurements
(Date:5/12/2016)... , May 12, 2016 WearablesResearch.com ... just published the overview results from the Q1 wave ... the recent wave was consumers, receptivity to a program ... data with a health insurance company. "We ... to share," says Michael LaColla , CEO of ...
(Date:4/28/2016)... April 28, 2016 First quarter 2016:   ... 966% compared with the first quarter of 2015 The ... 589.1 M (loss: 18.8) and the operating margin was 40% (-13) ... Cash flow from operations was SEK 249.9 M (21.2) ... guidance is unchanged, SEK 7,000-8,500 M. The operating margin ...
(Date:4/15/2016)... 2016  A new partnership announced today will ... decisions in a fraction of the time it ... high-value life insurance policies to consumers without requiring ... Force Diagnostics, rapid testing (A1C, Cotinine and HIV) ... pressure, weight, pulse, BMI, and activity data) available ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... - FACIT has announced the creation of a ... Propellon Therapeutics Inc. ("Propellon" or "the Company"), to ... of first-in-class WDR5 inhibitors for the treatment of ... an exciting class of therapies, possessing the potential ... patients. Substantial advances have been achieved with the ...
(Date:6/23/2016)... June, 23, 2016  The Biodesign Challenge (BDC), a ... ways to harness living systems and biotechnology, announced its ... in New York City . ... students, showcased projects at MoMA,s Celeste Bartos Theater during ... , MoMA,s senior curator of architecture and design, and ...
(Date:6/23/2016)... June 23, 2016 Apellis Pharmaceuticals, Inc. ... clinical trials of its complement C3 inhibitor, APL-2. ... multiple ascending dose studies designed to assess the ... subcutaneous injection in healthy adult volunteers. ... as a single dose (ranging from 45 to ...
(Date:6/23/2016)... ... June 23, 2016 , ... Regulatory Compliance ... consulting, provides a free webinar on Performing Quality Investigations: Getting to ... 12pm CT at no charge. , Incomplete investigations are still a major concern ...
Breaking Biology Technology: