Navigation Links
NIST issues first reference material for tissue engineering
Date:5/8/2009

The National Institute of Standards and Technology (NIST) last week issued its first reference materials to support the new and growing field of tissue engineering for medicine. The new NIST materials are samples of a typical tissue scaffold material that have been measured and documented by NIST for three different degrees of porosity.

Three-dimensional tissue scaffolds, under development for some years, are biodegradable materials that are meant to be implanted in the body to provide a structurally sound framework for the patients cells to implant and grow, in time repairing damaged tissue. The scaffolds are meant to be absorbed gradually by the body and replaced by normal tissue. Today they are used most commonly to help repair damaged bone, but other applications being studied.

In addition to biocompatibility and biodegradability, successful 3-D tissue scaffolds have a number of physical requirements. Porosity or pore size is one key factor. The pores in the scaffold must be large enough to permit cells to infuse the structure and receive nutrients, but healthy cell growth also depends on the cells immediate surroundings. If the pores are too large or spaced too far apart, cells will be unable to build the proper connections.

The three new NIST reference materials are disks approximately 20 millimeters across and 5 millimeters high formed of crisscrossed layers polyester struts approximately 200 micrometers in diameter. Varying the spacing of the struts in each layer resulted in three different average porosities for the disks: 47 percent (average strut spacing of 200 micrometers), 60 percent (300 micrometers), and 69 percent (450 micrometers). These span the common range of pore sizes typically required for tissue engineering applications.

The biodegradable polymer, polycaprolactone, originally was used for sutures, and was chosen for being relatively strong and stable when not exposed to water or sunlight. The material has been approved by the Food and Drug Administration for use in tissue engineering implants, but the NIST reference materials are not meant for use in the body.

The release of these reference materials culminates a multi-year effort involving input from the FDA, the National Institutes of Health and ASTM Working Group WK6507 Reference Scaffolds for Tissue Engineering.


'/>"/>

Contact: Michael Baum
michael.baum@nist.gov
301-975-2763
National Institute of Standards and Technology (NIST)
Source:Eurekalert  

Related biology news :

1. Global alliance of leading technological universities to address global societal issues
2. 3 Woods Hole scientific institutions forge alliance to address societal issues
3. Latest research on childrens issues featured at SRCD meeting
4. A new way to assemble cells into 3-D microtissues
5. High Performance, Low-Cost VoIP Chips Address Critical Performance Issues Such as Echo, Latency, and Packet Loss
6. SectorWatch.biz Issues Commentary for Investors of Homeland Defense Companies FOUR, MAGS, NSSC, PNTR, BCO, and CKP
7. Substantial work ahead for water issues, say scientists at ACS Final Report briefing
8. Stanford launches $100 million initiative to tackle energy issues
9. Issues at intersection of climate change and health impact global well-being
10. UD researchers show that plants can accumulate nanoparticles in tissues
11. Human genes sing different tunes in different tissues
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
NIST issues first reference material for tissue engineering
(Date:2/14/2017)... , Feb. 14, 2017  Wake Forest Baptist ... as its new chief executive officer (CEO). Freischlag joins ... John D. McConnell , M.D., who last year ... at the Medical Center, after leading it since 2008. ... full scope of Wake Forest Baptist,s academic health system, ...
(Date:2/10/2017)... , Feb 10, 2017 ... new report "Personalized Medicine - Scientific and Commercial Aspects" ... ... personalized medicine. Diagnosis is integrated with therapy for selection of ... on early detection and prevention of disease in modern medicine. ...
(Date:2/8/2017)... 7, 2017  Aware, Inc. (NASDAQ: AWRE ), ... financial results for its quarter and year ended December 31, ... 2016 was $3.9 million compared to $6.9 million in the ... of 2016 was $0.6 million compared to $2.6 million in ... quarter of 2016 was $0.5 million, or $0.02 per diluted ...
Breaking Biology News(10 mins):
(Date:3/24/2017)... , March 24, 2017 On ... trading session at 5,817.69, down 0.07%; the Dow Jones ... and the S&P 500 closed at 2,345.96, marginally dropping ... sectors closed in green, 4 sectors finished in red, ... Friday, Stock-Callers.com has initiated reports coverage on the following ...
(Date:3/23/2017)... ... March 23, 2017 , ... Lajollacooks4u is proud to announce it has become the premiere team-building ... challenges for companies around the world, such as Illumina, HP and Qualcomm, and is ranked ... its increasing popularity is due to its new team building format, a way for teams ...
(Date:3/23/2017)...  GlobeImmune, Inc. today announced it has entered into ... shares of its common stock to NantCell, Inc., a ... the sale of its common stock, NantCell has agreed ... GlobeImmune 200,000 shares, an estimated $2.0 million in value, ... pleased to enter into this strategic agreement with NantCell," ...
(Date:3/23/2017)... YORK , March 23, 2017 ... ... of death, putting significant strain on health care systems, in ... cancer diagnoses rises, so too does the development of innovative ... minimum side effects. Among the many types of cancer treatments, ...
Breaking Biology Technology: