Navigation Links
NIST issues first reference material for tissue engineering

The National Institute of Standards and Technology (NIST) last week issued its first reference materials to support the new and growing field of tissue engineering for medicine. The new NIST materials are samples of a typical tissue scaffold material that have been measured and documented by NIST for three different degrees of porosity.

Three-dimensional tissue scaffolds, under development for some years, are biodegradable materials that are meant to be implanted in the body to provide a structurally sound framework for the patients cells to implant and grow, in time repairing damaged tissue. The scaffolds are meant to be absorbed gradually by the body and replaced by normal tissue. Today they are used most commonly to help repair damaged bone, but other applications being studied.

In addition to biocompatibility and biodegradability, successful 3-D tissue scaffolds have a number of physical requirements. Porosity or pore size is one key factor. The pores in the scaffold must be large enough to permit cells to infuse the structure and receive nutrients, but healthy cell growth also depends on the cells immediate surroundings. If the pores are too large or spaced too far apart, cells will be unable to build the proper connections.

The three new NIST reference materials are disks approximately 20 millimeters across and 5 millimeters high formed of crisscrossed layers polyester struts approximately 200 micrometers in diameter. Varying the spacing of the struts in each layer resulted in three different average porosities for the disks: 47 percent (average strut spacing of 200 micrometers), 60 percent (300 micrometers), and 69 percent (450 micrometers). These span the common range of pore sizes typically required for tissue engineering applications.

The biodegradable polymer, polycaprolactone, originally was used for sutures, and was chosen for being relatively strong and stable when not exposed to water or sunlight. The material has been approved by the Food and Drug Administration for use in tissue engineering implants, but the NIST reference materials are not meant for use in the body.

The release of these reference materials culminates a multi-year effort involving input from the FDA, the National Institutes of Health and ASTM Working Group WK6507 Reference Scaffolds for Tissue Engineering.


Contact: Michael Baum
National Institute of Standards and Technology (NIST)

Related biology news :

1. Global alliance of leading technological universities to address global societal issues
2. 3 Woods Hole scientific institutions forge alliance to address societal issues
3. Latest research on childrens issues featured at SRCD meeting
4. A new way to assemble cells into 3-D microtissues
5. High Performance, Low-Cost VoIP Chips Address Critical Performance Issues Such as Echo, Latency, and Packet Loss
6. Issues Commentary for Investors of Homeland Defense Companies FOUR, MAGS, NSSC, PNTR, BCO, and CKP
7. Substantial work ahead for water issues, say scientists at ACS Final Report briefing
8. Stanford launches $100 million initiative to tackle energy issues
9. Issues at intersection of climate change and health impact global well-being
10. UD researchers show that plants can accumulate nanoparticles in tissues
11. Human genes sing different tunes in different tissues
Post Your Comments:
Related Image:
NIST issues first reference material for tissue engineering
(Date:10/26/2015)... NEWARK, Calif. , Oct. 26, 2015  Delta ... convenient biometric authentication to mobile and PC devices, announced ... Fujitsu,s smartphone, the arrows NX F-02H launched by NTT ... arrows NX F-02H is the second smartphone to include ... this technology in ARROWS NX F-04G in May 2015, ...
(Date:10/23/2015)... and GOLETA, California , October ... conference, BIOPAC and SensoMotoric Instruments (SMI) announce a mobile ... tracking data captured during interactive real-world tasks ... play integration of their established wearable solutions for eye ... synchronize gaze behavior captured with SMI Eye Tracking ...
(Date:10/22/2015)...  Synaptics (NASDAQ: SYNA ), a leading developer of human ... September 30, 2015. --> --> ... 66 percent over the comparable quarter last year to $470.0 million. ... million, or $0.62 per diluted share. --> ... of fiscal 2016 grew 39 percent over the prior year period ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... ... November 25, 2015 , ... Jessica Richman and ... early in their initial angel funding process. Now, they are paying it forward ... make early stage investments in the microbiome space. In this, they join ...
(Date:11/24/2015)... /CNW/ - iCo Therapeutics ("iCo" or "the Company") (TSX-V: ... the quarter ended September 30, 2015. Amounts, unless ... presented under International Financial Reporting Standards ("IFRS"). ... Andrew Rae , President & CEO of ... only value enriching for this clinical program, but ...
(Date:11/24/2015)... , November 24, 2015 ... new market research report "Oligonucleotide Synthesis Market by Product ... (PCR, Gene Synthesis, Diagnostic, DNA, RNAi), End-User (Research, Pharmaceutical ... published by MarketsandMarkets, the market is expected to reach ... in 2015, at a CAGR of 10.1% during the ...
(Date:11/24/2015)... , Nov. 24, 2015  Tikcro Technologies Ltd. (OTCQB: TIKRF) today ... December 29, 2015 at 11:00 a.m. Israel time, ... Tower, 98 Yigal Allon Street, 36 th Floor, Tel ... Eric Paneth and Izhak Tamir to the Board ... Skaliter as external directors; , approval of an amendment to certain ...
Breaking Biology Technology: