Navigation Links
NIST issues first reference material for tissue engineering
Date:5/8/2009

The National Institute of Standards and Technology (NIST) last week issued its first reference materials to support the new and growing field of tissue engineering for medicine. The new NIST materials are samples of a typical tissue scaffold material that have been measured and documented by NIST for three different degrees of porosity.

Three-dimensional tissue scaffolds, under development for some years, are biodegradable materials that are meant to be implanted in the body to provide a structurally sound framework for the patients cells to implant and grow, in time repairing damaged tissue. The scaffolds are meant to be absorbed gradually by the body and replaced by normal tissue. Today they are used most commonly to help repair damaged bone, but other applications being studied.

In addition to biocompatibility and biodegradability, successful 3-D tissue scaffolds have a number of physical requirements. Porosity or pore size is one key factor. The pores in the scaffold must be large enough to permit cells to infuse the structure and receive nutrients, but healthy cell growth also depends on the cells immediate surroundings. If the pores are too large or spaced too far apart, cells will be unable to build the proper connections.

The three new NIST reference materials are disks approximately 20 millimeters across and 5 millimeters high formed of crisscrossed layers polyester struts approximately 200 micrometers in diameter. Varying the spacing of the struts in each layer resulted in three different average porosities for the disks: 47 percent (average strut spacing of 200 micrometers), 60 percent (300 micrometers), and 69 percent (450 micrometers). These span the common range of pore sizes typically required for tissue engineering applications.

The biodegradable polymer, polycaprolactone, originally was used for sutures, and was chosen for being relatively strong and stable when not exposed to water or sunlight. The material has been approved by the Food and Drug Administration for use in tissue engineering implants, but the NIST reference materials are not meant for use in the body.

The release of these reference materials culminates a multi-year effort involving input from the FDA, the National Institutes of Health and ASTM Working Group WK6507 Reference Scaffolds for Tissue Engineering.


'/>"/>

Contact: Michael Baum
michael.baum@nist.gov
301-975-2763
National Institute of Standards and Technology (NIST)
Source:Eurekalert  

Related biology news :

1. Global alliance of leading technological universities to address global societal issues
2. 3 Woods Hole scientific institutions forge alliance to address societal issues
3. Latest research on childrens issues featured at SRCD meeting
4. A new way to assemble cells into 3-D microtissues
5. High Performance, Low-Cost VoIP Chips Address Critical Performance Issues Such as Echo, Latency, and Packet Loss
6. SectorWatch.biz Issues Commentary for Investors of Homeland Defense Companies FOUR, MAGS, NSSC, PNTR, BCO, and CKP
7. Substantial work ahead for water issues, say scientists at ACS Final Report briefing
8. Stanford launches $100 million initiative to tackle energy issues
9. Issues at intersection of climate change and health impact global well-being
10. UD researchers show that plants can accumulate nanoparticles in tissues
11. Human genes sing different tunes in different tissues
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
NIST issues first reference material for tissue engineering
(Date:2/2/2016)... , Feb. 2, 2016 This BCC ... bioinformatic market by reviewing the recent advances in ... that drive the field forward. Includes forecast through ... Identify the challenges and opportunities that exist in ... software solution developers, as well as IT and ...
(Date:2/2/2016)... 2016 Technology Enhancements Accelerate Growth of X-ray Imaging ... digital and computed radiography markets in Thailand ... Indonesia (TIM). It provides an in-depth ... well as regional market drivers and restraints. The study ... and market attractiveness, both for digital and computed radiography. ...
(Date:2/2/2016)... Feb. 2, 2016  Based on its recent ... Sullivan recognizes US-based Intelligent Retinal Imaging Systems (IRIS) ... Award for New Product Innovation. IRIS, a prominent ... North America , is poised to set ... diabetic retinopathy market. The IRIS technology presents superior ...
Breaking Biology News(10 mins):
(Date:2/9/2016)... (PRWEB) , ... February 09, 2016 , ... ... its latest innovations on its free and validated Electronic Data Capture (EDC) system ... the Outsourcing in Clinical Trials West Coast 2016 Conference in San Mateo, California ...
(Date:2/9/2016)... 9, 2016  DNAtrix, a clinical stage, ... announced that its lead product, DNX-2401, has ... an orphan medicinal product for the treatment ... glioma, strikes approximately 25,000 people a year ... http://photos.prnewswire.com/prnh/20160208/330986LOGO --> http://photos.prnewswire.com/prnh/20160208/330986LOGO ...
(Date:2/9/2016)... Feb. 9, 2016 ... 2016", report provides in depth insights on ... around the Protein-Tyrosine Phosphatase 1B (PTP1B) Inhibitors. ... in various stages of development including Discovery, ... III and Preregistration. Report covers the product ...
(Date:2/8/2016)... 8, 2016 Novan, Inc. today announced that Director ... of Directors of Novan. In addition, Robert Keegan has ... North Carolina . --> North Carolina ... it received a total of $32.8 million of net proceeds in ... investor network originating throughout the Research Triangle area of ...
Breaking Biology Technology: