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NIST cell membrane model studied as future diagnostic tool
Date:1/30/2014

igingly created pores in the test membranes, which in turn altered the electrochemical behavior of the membranes in a way that could be detected in real time by a sensitive technique called electrochemical impedance spectroscopy (EIS).

The researchers found that they could detect the presence of VLY down to 28 nanograms (billionths of a gram) per milliliter, a four-fold improvement over antibody detection methods now in use. The speed of detection also is faster, with the tBLM-EIS system yielding results in hours rather than days. Additionally, different G. vaginalis strains produce different amounts of VLY, so in many cases, the corresponding EIS readings can help define the specific type of bacteria present in an infection.

Now that they have proven the viability of the tBLM-EIS detection system, the researchers plan to begin tests on clinical samples early this year.


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Contact: Michael E. Newman
michael.newman@nist.gov
301-975-3025
National Institute of Standards and Technology (NIST)
Source:Eurekalert  

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