Navigation Links
NIH renews Nanomedicine Center focused on treating single-gene disorders for $16.1 million
Date:10/28/2010

The Georgia Tech-led Nanomedicine Center for Nucleoprotein Machines has received an award of $16.1 million for five years as part of its renewal by the National Institutes of Health (NIH). The eight-institution research team plans to pursue development of a clinically viable gene correction technology for single-gene disorders and demonstrate the technology's efficacy with sickle cell disease.

Sickle cell disease is a genetic condition present at birth that affects more than 70,000 Americans. It involves a single altered gene that produces abnormal hemoglobin the protein that carries oxygen in the blood. In sickle cell disease, red blood cells become hard, sticky and "C" shaped. Sickle cells die early, which causes a constant shortage of red blood cells. The abnormal cells also clog the flow in small blood vessels, causing chronic pain and other serious problems such as infections and acute chest syndrome.

"Even though researchers know sickle cell disease is caused by a single A to T mutation in the beta-globin gene, there is no widely available cure," said center director Gang Bao, the Robert A. Milton Chair in Biomedical Engineering in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. "By directly and precisely fixing the single mutation, we hope to reduce or eliminate the sickle cell population in an individual's blood stream and replace the sickle cells with healthy red blood cells."

The center is one of eight NIH Nanomedicine Development Centers established in 2005 and 2006, a key initiative of the NIH's long-term nanomedicine research goals. The centers have highly multidisciplinary scientific teams that include biologists, physicians, mathematicians, engineers and computer scientists. Through an intense competition, the NIH selected four centers for second phase funding, including the one led by Georgia Tech.

In addition to experts in the Coulter Department of Biom
'/>"/>

Contact: Abby Vogel Robinson
abby@innovate.gatech.edu
404-385-3364
Georgia Institute of Technology Research News
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. NY Gov. Paterson renews commitment to stem cell research in visit to Cold Spring Harbor Laboratory
2. HHMI renews grant for Rices global health program
3. UT nanomedicine project to be tested in space
4. All-in-1 nanoparticle: A Swiss Army knife for nanomedicine
5. Toward a nanomedicine for brain cancer
6. Findings show nanomedicine promising for treating spinal cord injuries
7. Nanomedicine: Ending hit and miss design
8. NSF funds new Center for the Physics of Living Cells at Illinois
9. Rice University establishes National Corrosion Center
10. New center will focus environmental debate and produce solutions for action
11. Research center to free chemistry from Earths bonds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
NIH renews Nanomedicine Center focused on treating single-gene disorders for $16.1 million
(Date:3/22/2017)... , March 21, 2017 ... Cloud used by retailers such as 1-800-Flowers and ... platform — Product Recommendations and Replenishment. Using Optimove,s machine ... more personalized product and replenishment recommendations to their ... also on predictions of customer intent drawn from ...
(Date:3/16/2017)... Germany , March 16, 2017 CeBIT 2017 - Against identity ... Continue Reading ... Used combined in one project, multi-biometric solutions provide ... Used ... Systems) ...
(Date:3/7/2017)... , March 7, 2017 Brandwatch , the ... by The Prince,s Trust to uncover insights to support ... The Trust. The UK,s leading youth charity will be ... campaign results and get a better understanding of the topics and ... ...
Breaking Biology News(10 mins):
(Date:4/20/2017)... ... April 20, 2017 , ... As part of ... explore challenging patient cases when screening for direct oral anticoagulant. When patients taking ... need for bridging parental anticoagulation especially for those at high risk of thrombosis ...
(Date:4/20/2017)... ... ... NetDimensions appoints Bill Mastin, a learning technology veteran, as its new Senior Vice ... technologies industry, Mastin joins NetDimensions from the New York office of learning and engagement ... served as SVP of the North America offices and prior to that, he held ...
(Date:4/20/2017)... 2017 Dutch philosopher Koert van Mensvoort - founder ... University of Technology in Eindhoven - has written a ,Letter to Humanity, ... on humanity to avoid becoming a slave and victim to its own technology, ... ... Dutch philosopher Koert van Mensvoort – founder of the Next Nature Network and ...
(Date:4/19/2017)... ... April 18, 2017 , ... Alisa Wright, founder and CEO ... from the Purdue College of Pharmacy in Lafayette, Indiana. , The Distinguished Alumni ... achievements in their careers and other scientific endeavors. , Wright began her career ...
Breaking Biology Technology: