Navigation Links
NIH renews Nanomedicine Center focused on treating single-gene disorders for $16.1 million

The Georgia Tech-led Nanomedicine Center for Nucleoprotein Machines has received an award of $16.1 million for five years as part of its renewal by the National Institutes of Health (NIH). The eight-institution research team plans to pursue development of a clinically viable gene correction technology for single-gene disorders and demonstrate the technology's efficacy with sickle cell disease.

Sickle cell disease is a genetic condition present at birth that affects more than 70,000 Americans. It involves a single altered gene that produces abnormal hemoglobin the protein that carries oxygen in the blood. In sickle cell disease, red blood cells become hard, sticky and "C" shaped. Sickle cells die early, which causes a constant shortage of red blood cells. The abnormal cells also clog the flow in small blood vessels, causing chronic pain and other serious problems such as infections and acute chest syndrome.

"Even though researchers know sickle cell disease is caused by a single A to T mutation in the beta-globin gene, there is no widely available cure," said center director Gang Bao, the Robert A. Milton Chair in Biomedical Engineering in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. "By directly and precisely fixing the single mutation, we hope to reduce or eliminate the sickle cell population in an individual's blood stream and replace the sickle cells with healthy red blood cells."

The center is one of eight NIH Nanomedicine Development Centers established in 2005 and 2006, a key initiative of the NIH's long-term nanomedicine research goals. The centers have highly multidisciplinary scientific teams that include biologists, physicians, mathematicians, engineers and computer scientists. Through an intense competition, the NIH selected four centers for second phase funding, including the one led by Georgia Tech.

In addition to experts in the Coulter Department of Biom

Contact: Abby Vogel Robinson
Georgia Institute of Technology Research News

Page: 1 2 3 4

Related biology news :

1. NY Gov. Paterson renews commitment to stem cell research in visit to Cold Spring Harbor Laboratory
2. HHMI renews grant for Rices global health program
3. UT nanomedicine project to be tested in space
4. All-in-1 nanoparticle: A Swiss Army knife for nanomedicine
5. Toward a nanomedicine for brain cancer
6. Findings show nanomedicine promising for treating spinal cord injuries
7. Nanomedicine: Ending hit and miss design
8. NSF funds new Center for the Physics of Living Cells at Illinois
9. Rice University establishes National Corrosion Center
10. New center will focus environmental debate and produce solutions for action
11. Research center to free chemistry from Earths bonds
Post Your Comments:
Related Image:
NIH renews Nanomedicine Center focused on treating single-gene disorders for $16.1 million
(Date:11/12/2015)... LONDON , Nov. 11, 2015   ... and reliable analytical tools has been paving the ... and qualitative determination of discrete analytes in clinical, ... sensors are being predominantly used in medical applications, ... and environmental sectors due to continuous emphasis on ...
(Date:11/9/2015)... , Nov. 09, 2015 ... addition of the "Global Law Enforcement ... offering. --> ) has ... Law Enforcement Biometrics Market 2015-2019" report ... and Markets ( ) has announced ...
(Date:10/29/2015)... , Oct. 29, 2015   MedNet Solutions , ... entire spectrum of clinical research, is pleased to announce ... Tech Association (MHTA) as one of only three finalists ... "Software – Small and Growing" category. The Tekne Awards honor ... have shown superior technology innovation and leadership. ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... QUEBEC CITY , Nov. 24, 2015 /PRNewswire/ - ... the request of IIROC on behalf of the Toronto ... this news release there are no corporate developments that ... price. --> --> ... --> . --> Aeterna Zentaris ...
(Date:11/24/2015)... ... November 24, 2015 , ... The Academy of Model Aeronautics ... (SIG), MultiGP, also known as Multirotor Grand Prix, to represent the First–Person View (FPV) ... Many AMA members have embraced this type of racing and several new model aviation ...
(Date:11/24/2015)... CITY , Nov. 24, 2015 /PRNewswire/ - ... "Company") announced today that the remaining 11,000 post-share ... Share Purchase Warrants (the "Series B Warrants") subject ... were exercised on November 23, 2015, which will ... Shares.  After giving effect to the issuance of ...
(Date:11/24/2015)... ... November 24, 2015 , ... Creation Technologies would like ... to Deloitte's 2015 Technology Fast 500 list of the fastest growing companies in ... Class II medical device that speeds up orthodontic tooth movement by as much ...
Breaking Biology Technology: