Navigation Links
NIH recognizes Clemson nanotechnology for molecule tracking
Date:10/31/2007

CLEMSON The National Institutes of Health has awarded two Clemson chemistry faculty nearly $1 million to detect, track and image the interior of cells. Jason McNeill and Ken Christensen will receive the $960,000 grant to develop polymer dot nanoparticles for tracking single molecules in live cells.

The development of techniques for following individual molecules within cells is important because scientists could use this technology to determine the bodys defenses against invading viruses and bacteria or how proteins operate within the cell. The technology also could help doctors pinpoint the exact location of cancer cells in order to better focus treatment and minimize damage to healthy tissue. Other possible targets of investigation include plaques and fibrils in the brain associated with Alzheimer's disease and mad cow disease.

For the last decade, scientists around the globe have worked to develop and refine highly fluorescent nanoparticles that light up when bathed with laser light, enabling scientists to pinpoint the location of an individual molecule inside a living cell or tissue.

Recently, Clemson chemists developed novel, highly fluorescent nanoparticles called polymer dots that can be attached to individual proteins, DNA or invading microbes. According to chemist Jason McNeill, the polymer dot particles are hundreds or thousands of times brighter than conventional fluorescent dyes.

We were initially interested in developing polymer semiconductor nanoparticles for making inexpensive, highly efficient solar cells and light-emitting displays. When we aimed a laser at the particles in a microscope, we were surprised to see individual particles light up very brightly, said McNeill.

When I heard about these extremely bright particles, my group was very interested in working with Dr. McNeill to push this technology into live cell imaging, said Christensen. Biology is often driven by new discoveries in chemistry
'/>"/>

Contact: Jason McNeill
mcneill@clemson.edu
864-656-4065
Clemson University
Source:Eurekalert

0

GOOD

Page: 1 2

Related biology news :

1. What recognizes what in plant disease resistance?
2. Mimicking how the brain recognizes street scenes
3. New details on how the immune system recognizes influenza
4. Revolutionary nanotechnology illuminates brain cells at work
5. Nanotechnology to provide portable genetic risk detection
6. Nanotechnology may find disease before it starts
7. Nanotechnology being used to improve biocompatibility of human prosthetics and implants
8. Silver bullet: UGA researchers use laser, nanotechnology to rapidly detect viruses
9. Nanotechnology propels advances in regenerative medicine research
10. New nanotechnology able to examine single molecules, aiding in determining gene expression
11. Nanotechnology shows promise as next wrinkle fighter

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/8/2009)...v. 8, 2009) The loss of a gene through deletion o...with significant abnormalities in learning and beh...lor College of Medicine ( www.bcm.edu ) in a repor... Genetics . , "This research goes about 95 perce...fic group of individuals to this gene," said Dr. A...
(Date:11/6/2009)...stration is now open for the Society of Interventi...logy (IO) Therapies" Webinar, which will provide t...r treatment of liver tumors, kidney tumor ablation...zation of physicians, scientists and allied health...h through pioneering advances in image-guided ther...
(Date:11/6/2009)...ts generally live in harmony with their arboreal h... out of space in their trees of choice, the ants c...esearch, published in the November issue of the A... ants bore into live trees, and it reopens a centu...nd plants. , Ants and certain species of plants ...
Breaking Biology News(10 mins):Developmental delay could stem from nicotinic receptor deletion 2Society of Interventional Radiology hosts oncology therapies Webinar, offers resources 2Ants are friendly to some trees, but not others 2Bolton School of Nursing at CWRU receives 243 7 million in federal stimulus funding 59933 1Bolton School of Nursing at CWRU receives 243 7 million in federal stimulus funding 59933 2Radiation Treatments Made Safer for Cancer Patients 59930 1Radiation Treatments Made Safer for Cancer Patients 59930 2Senetek Implements New Corporate Communication Policy 59927 1Senetek Implements New Corporate Communication Policy 59927 2
...on system developed by Carnegie Mellon University ...ama Desert, according to results being presented a...March 14-18 in Houston. This marks the first time ...o identify life in this harsh region, which serves...ed in future Mars missions. , "Our life detection ...
...like "water balloons" composed of artificially cre... membranes ?have revealed unexpected behavior in t...a paradigm-shifting change in science,s understand...stems. , Arizona State University chemists Mark Ha...ave a tendency to form tube-like extensions in the...
...unodeficiency virus (HIV), highly active antiretro...s of Kaposi sarcoma and non-Hodgkin lymphoma, acco...Journal of the National Cancer Institute. , Studie...e (AIDS) have reported increased risks of several ...phoma, and, to a lesser extent, anal cancer, invas...
Other Biology News:Robot-based system developed at Carnegie Mellon detects life in Chile's Atacama desert 2Robot-based system developed at Carnegie Mellon detects life in Chile's Atacama desert 3Robot-based system developed at Carnegie Mellon detects life in Chile's Atacama desert 4Antiretroviral therapy may prevent excess risk of some cancers in people with HIV 2
(Date:11/6/2009)..., Mass., Nov. 6 Myriant Technologi...loper and manufacturer of renewable bio-chemicals...chnology provider Uhde GmbH, one of the world,s le...nounced an alliance for the engineering, procureme...Succinic Acid plants based on renewable feedstocks...
(Date:11/6/2009)... VALLEY, Calif., Nov. 6 Calbiotech...Small Business Innovative Research (SBIR) Phase I ...erial command. Under terms of the agreement, Calbi...) for the diagnosis of Dengue virus. ,, Deng...ents a major threat to military forces deployed to...
(Date:11/6/2009)... The agenda for Arrowhead’s 201...hich is set to take place on February 22-24, 2010 ... day conference we will highlight key issues in fo... share their experiences. , ... agenda for Arrowhead’s 2010 Personalized M...
(Date:11/5/2009)...GTON, Colo., Nov. 5 The endangered... the western U.S. This rare carnivore feeds on pr...e to plague and often entire population die-offs i...ce (FWS) has implemented a ferret breeding program...nto their formerly native habitat. Unfortunately,...
Breaking Biology Technology:Myriant Technologies LLC, Uhde Corporation of America and Uhde GmbH Announce Alliance for Engineering, Procurement & Construction of World Scale Renewable Succinic Acid Plants 2Myriant Technologies LLC, Uhde Corporation of America and Uhde GmbH Announce Alliance for Engineering, Procurement & Construction of World Scale Renewable Succinic Acid Plants 3Calbiotech Awarded U.S. Army Phase I SBIR Research Contract to Develop Analyte Specific Reagents for the Diagnosis of Dengue Fever Virus 2Leaders in Biopharma and Molecular Diagnostics to Discuss Key Issues and Opportunities in Forming Partnerships at 2010 Personalized Medicine Partnerships Conference 2Leaders in Biopharma and Molecular Diagnostics to Discuss Key Issues and Opportunities in Forming Partnerships at 2010 Personalized Medicine Partnerships Conference 3Colorado Companies Team Up With U.S. Fish & Wildlife Service to Protect Black-Footed Ferret 2
... Initiative, Based on Advanced WiMAX Broadband Wir...ss to Kindergartens, Elementary Schools and the ...ACH TIKVA, Israel, January 8 012,Smile.Communicat...d provider,of communication services in Israel, to...istry of Communications, Intel Corporation (NYSE: ...
...ISON, N.J., Jan. 7 Quest Diagnostics,Incorporated...iagnostic,testing, information and services, annou...ual JPMorgan Healthcare Conference on Tuesday, Jan...cisco, California. The Quest,Diagnostics presentat...me., The presentation will be webcast live during...
...RENCE, Mass., Jan. 7 NxStage Medical, Inc.,(Nasda...ialysis products,today announced that it has signe...DVA ) to continue to supply DaVita,s dialysis cent...sets, subject to certain terms and,conditions. Saf...patients,blood during the vast majority of chronic...
Other Biology Technology:Israel's Ministry of Communications, 012 Smile.Communications, Intel and Alvarion Join in Launching WiMAX Initiative for Sderot, a City in the Western Negev 2Israel's Ministry of Communications, 012 Smile.Communications, Intel and Alvarion Join in Launching WiMAX Initiative for Sderot, a City in the Western Negev 3Israel's Ministry of Communications, 012 Smile.Communications, Intel and Alvarion Join in Launching WiMAX Initiative for Sderot, a City in the Western Negev 4Israel's Ministry of Communications, 012 Smile.Communications, Intel and Alvarion Join in Launching WiMAX Initiative for Sderot, a City in the Western Negev 5Quest Diagnostics to Speak at the 26th Annual JPMorgan Healthcare Conference 2NxStage Medical Announces Needle Supply Agreement with DaVita 2
Qplate from Sophion Bioscience
...ftware, a multitasking application capable of dyna...g and operation of lab automation workcells easy f...odification by programmers. • Users create ...t. If you can build a flowchart, you can write a S...
...demands continue to grow, the need for greater det...e necessary, especially when discerning very simil...ve C1si Confocal Microscope System gives you a lev...ot available in conventional confocal systems, wit...
...sed assay kit provides complete components includi...ent detection of DNA fragmentation in cultured cel...in the procedure provides greater sensitivity than...can be analyzed by fluorescence microscopy or flow...
Biology Products: