Historically, microbes have been studied in the laboratory as cultures of isolated species. Microbial growth is dependent upon a very specific natural environment, and it is often difficult to duplicate these conditions in a laboratory. Therefore, the development of novel and innovative technologies is needed to improve and refine the identification and characterization of the microbes that comprise the complex mixtures found in and on our bodies.
The principal investigators who will develop new technologies, their approximate funding levels and their areas of research are:
Emma Allen-Vercoe, Ph.D., University of Guelph, Ontario
$179,000 (2 years)
A Method to Sort and Enrich the as-yet Uncultured Bacterial Species from the Human Distal Gut
Ronald Davis, Ph.D., Stanford University, Palo Alto, Calif.
$440,000 (2 years)
Isolation, Selection and Polony Amplification of Single Cells in a Gel Matrix
David Fredricks, M.D., Fred Hutchinson Cancer Research Center, Seattle.
$2 million (3 years)
Novel Cultivation Methods for the Domestication of Vaginal Bacteria
Rustem Ismagilov, Ph.D., University of Chicago
$1.1 million (3 years)
Confining Single Cells to Enhance and Target Cultivation of Human Microbiome
Kim Lewis, Ph.D., Northeastern University, Boston
$1.2 million (3 years)
Culturing Uncultivatable Gut Microorganisms
John Nelson, Ph.D., General Electric Global Research, Niskayuna, N.Y.
$538,000 (2 years)
Tools for Human Microbiome Studies
Analysis of the seq
|Contact: Geoff Spencer|
NIH/National Human Genome Research Institute