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NIH grant will allow researchers to look for viral cause of most severe form of multiple sclerosis
Date:10/12/2011

to brain tissue from a population of controls, including normal patients and people with other neurologic diseases.

The sequencing data generated will then be analyzed for viral genetic material in order to identify viruses that are unique to the brain tissue of people with primary progressive MS.

MS is classified into four types, which differ in symptom intensity and rate of disease progression. While treatment has been effective for some forms of MS, the standard medications for MS have not been shown to slow the progression of neurologic decline in people with primary progressive multiple sclerosis (PPMS). Identifying viruses that might play a role in the development of PPMS could eventually lead to the development of screening tests, prevention, or anti-viral treatments for the disease.

"Currently, there is no approved or highly effective treatment for PPMS," says Kriesel. "The goal of our research is to define a cause for PPMS, so that future investigation can be directed at developing medicines that can slow or stop the progression of this devastating neurologic disease."


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Contact: John D. Kriesel, M.D.
801-585-7314
University of Utah Health Sciences
Source:Eurekalert

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