Principal Investigator: Arul Chinnaiyan, M.D., Ph.D.
Dr. Chinnaiyan and his team will sequence the genomes of tumors from 500 patients with advanced sarcoma or other rare cancers to discover new information about genomic alterations, with the goal of eventually customizing therapies. Few clinical trials have been conducted in most rare cancers, and scientists would like to know more about the genetic underpinnings of these diseases. Investigators also plan to evaluate the patient consent process, and the delivery and use of genome sequencing results.
Principal Investigators: Gail Jarvik, M.D., Ph.D., Wylie Burke, M.D., Ph.D., Debbie Nickerson, Ph.D., Peter Tarczy-Hornoch, M.D.
Dr. Jarvik and her colleagues at the University of Washington will lead the coordinating center responsible for pulling together all of the scientific teams, helping to organize studies, interpreting study results and helping groups focus on common goals. The coordinating center team members bring their own expertise in clinical genetics, genome sequencing, bioinformatics and ethics.
These awards are supported by NIH grants 1UM1HG006508-01AL, 1UM1HG007292-01, 1UM1HG007301-01, and 1U01HG007307-01.
|Contact: Steven Benowitz|
NIH/National Human Genome Research Institute