Navigation Links
NIH-funded scientists sequence genomes of lyme disease bacteria

WHAT: Scientists supported by the National Institutes of Health (NIH) have determined the complete genetic blueprints for 13 different strains of Borrelia burgdorferi, the bacteria that cause Lyme disease. The achievement should lead to a better understanding of how genetic variations among strains may result in different courses of illness in people with Lyme disease, the most common tickborne disease in North America. The wealth of new genetic data will also help scientists develop improved ways to diagnose, treat and prevent Lyme disease.

The first genome of a strain of B. burgdorferi was sequenced more than 10 years ago. The 13 newly sequenced strains include ones isolated from humans and ticks and represent a range of geographic origins. Together, the genomes provide a more complete picture of scope of natural variations in the microbe and the disease it causes.

The sequencing and analysis was led by Claire M. Fraser-Liggett, Ph.D., of the University of Maryland School of Medicine, and was performed at a Microbial Sequencing Center funded by the NIH's National Institute of Allergy and Infectious Diseases (NIAID). The research project was initiated by Steven E. Schutzer, M.D., of the University of Medicine and Dentistry of New Jersey-New Jersey Medical School, an NIAID grantee.

Additional support was provided by the National Institute of General Medical Sciences and the National Center for Research Resources, both components of NIH.

ARTICLE: SE Schutzer et al. Whole genome sequences of thirteen isolates of Borrelia burgdorferi. J. Bacteriology DOI: 10.1128/JB.01158-01 (2010).

WHO: Joseph J. Breen, Ph.D., Bacteriology Program Officer, Division of Microbiology and Infectious Diseases, NIAID, is available to comment.


Contact: Anne A. Oplinger
NIH/National Institute of Allergy and Infectious Diseases

Page: 1

Related biology news :

1. NIH-funded researchers sequence exomes of 12 people
2. NIH-funded studies aim to prevent, treat childhood obesity
3. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
4. Scientists identify novel inhibitor of human microRNA
5. Argonne scientists peer into heart of compound that may detect chemical, biological weapons
6. MU scientists go green with gold, distribute environmentally friendly nanoparticles
7. Scientists identify gene that may contribute to improved rice yield
8. Scientists discover why a mothers high-fat diet contributes to obesity in her children
9. MU scientists see how HIV matures into an infection
10. Earth scientists keep an eye on Texas
11. Thinking it through: Scientists call for policy to guide biofuels industry toward sustainability
Post Your Comments:
(Date:10/29/2015)... 29, 2015  Rubicon Genomics, Inc., today announced ... of its DNA library preparation products, including the ... ThruPLEX Plasma-seq kit. ThruPLEX Plasma-seq has been optimized ... NGS libraries for liquid biopsies--the analysis of cell-free ... applications in cancer and other conditions. Eurofins Scientific ...
(Date:10/27/2015)... YORK , Oct. 27, 2015 In ... major issues of concern for various industry verticals such ... is due to the growing demand for secure & ... in various ,sectors, such as hacking of bank accounts, ... for electronic equipment such as PC,s, laptops, and smartphones ...
(Date:10/26/2015)... and LAS VEGAS , Oct. ... Labs , an innovator in modern authentication and a ... announced the launch of its latest version of the ... enabling organizations to use standards-based authentication that supports existing ... S3 Authentication Suite is ideal for organizations deploying customer-facing ...
Breaking Biology News(10 mins):
(Date:12/1/2015)... , Dec. 1, 2015 Cepheid (Nasdaq: ... its participation at the Piper Jaffray Healthcare Conference in ... morning, the Company is reaffirming its outlook for the ... 2016, in addition to discussing longer term business model ... Chief Executive Officer.  "We continue to be the fastest ...
(Date:12/1/2015)... 2015 ) ... U.K. Virology and Bacteriology Testing Market: Sales ... Supplier Shares by Test, Innovative Technologies, Competitive ... --> ) has announced ... and Bacteriology Testing Market: Sales and Volume ...
(Date:11/30/2015)... , ... November 30, 2015 , ... Global Stem Cells Group announced the ... in the cities of Arica and Iquique in northern Chile. The facilities are part of ... the most advanced protocols and techniques in stem cell medicine to patients from around the ...
(Date:11/30/2015)... 2015  Culprits beware, a University at Albany ... Halámek, is taking crime scene fingerprint identification to ... -->   --> ... --> --> Halámek and his ... straightforward concept for identifying whether a culprit is ...
Breaking Biology Technology: