Navigation Links
NIH-funded scientists sequence genomes of lyme disease bacteria
Date:10/18/2010

WHAT: Scientists supported by the National Institutes of Health (NIH) have determined the complete genetic blueprints for 13 different strains of Borrelia burgdorferi, the bacteria that cause Lyme disease. The achievement should lead to a better understanding of how genetic variations among strains may result in different courses of illness in people with Lyme disease, the most common tickborne disease in North America. The wealth of new genetic data will also help scientists develop improved ways to diagnose, treat and prevent Lyme disease.

The first genome of a strain of B. burgdorferi was sequenced more than 10 years ago. The 13 newly sequenced strains include ones isolated from humans and ticks and represent a range of geographic origins. Together, the genomes provide a more complete picture of scope of natural variations in the microbe and the disease it causes.

The sequencing and analysis was led by Claire M. Fraser-Liggett, Ph.D., of the University of Maryland School of Medicine, and was performed at a Microbial Sequencing Center funded by the NIH's National Institute of Allergy and Infectious Diseases (NIAID). The research project was initiated by Steven E. Schutzer, M.D., of the University of Medicine and Dentistry of New Jersey-New Jersey Medical School, an NIAID grantee.

Additional support was provided by the National Institute of General Medical Sciences and the National Center for Research Resources, both components of NIH.

ARTICLE: SE Schutzer et al. Whole genome sequences of thirteen isolates of Borrelia burgdorferi. J. Bacteriology DOI: 10.1128/JB.01158-01 (2010).

WHO: Joseph J. Breen, Ph.D., Bacteriology Program Officer, Division of Microbiology and Infectious Diseases, NIAID, is available to comment.


'/>"/>

Contact: Anne A. Oplinger
aoplinger@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
Source:Eurekalert

Page: 1

Related biology news :

1. NIH-funded researchers sequence exomes of 12 people
2. NIH-funded studies aim to prevent, treat childhood obesity
3. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
4. Scientists identify novel inhibitor of human microRNA
5. Argonne scientists peer into heart of compound that may detect chemical, biological weapons
6. MU scientists go green with gold, distribute environmentally friendly nanoparticles
7. Scientists identify gene that may contribute to improved rice yield
8. Scientists discover why a mothers high-fat diet contributes to obesity in her children
9. MU scientists see how HIV matures into an infection
10. Earth scientists keep an eye on Texas
11. Thinking it through: Scientists call for policy to guide biofuels industry toward sustainability
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2016)... , April 28, 2016 First quarter ... (139.9), up 966% compared with the first quarter of 2015 ... totaled SEK 589.1 M (loss: 18.8) and the operating margin was ... (loss: 0.32) Cash flow from operations was SEK 249.9 ... 2016 revenue guidance is unchanged, SEK 7,000-8,500 M. The ...
(Date:4/26/2016)... Research and Markets has announced ... 2016-2020"  report to their offering.  , ,     (Logo: ... analysts forecast the global multimodal biometrics market to ... period 2016-2020.  Multimodal biometrics is being ... the healthcare, BFSI, transportation, automotive, and government for ...
(Date:4/15/2016)... , April 15, 2016  A new ... make more accurate underwriting decisions in a fraction ... timely, competitively priced and high-value life insurance policies ... screenings. With Force Diagnostics, rapid testing ... lifestyle data readings (blood pressure, weight, pulse, BMI, ...
Breaking Biology News(10 mins):
(Date:5/26/2016)... READING, England , May 26, 2016 ... a leading global provider of clinical, commercial and ... organisations and TranScrip ( http://www.transcrip-partners.com ), a renowned ... product lifecycle, today announced the extension of their ...      (Logo: http://photos.prnewswire.com/prnh/20141208/720248 ) , ...
(Date:5/26/2016)... , May 26, 2016 Despite the ... value in this space. Today,s pre-market research on ActiveWallSt.com directs ... Health Inc. (NASDAQ: RDUS ), Cerus Corp. (NASDAQ: ... ARWR ), and Five Prime Therapeutics Inc. (NASDAQ: ... briefings at: http://www.activewallst.com/ On ...
(Date:5/26/2016)... San Diego, CA (PRWEB) , ... May 26, ... ... assay development and manufacturing company, today announced several positive developments that position the ... As a result of the transaction, Craig F. Kinghorn has been appointed ...
(Date:5/25/2016)... ... May 25, 2016 , ... Lajollacooks4u has become a rising hotspot for specialized ... of its top attractions. Fortune 500 companies, such as Illumina, Hewlett-Packard, Qualcomm and ... intimate team-building experience. , Each event kicks off with an olive oil and salt-tasting ...
Breaking Biology Technology: