Navigation Links
NIH expands network focused on how genes affect drug responses
Date:9/7/2010

The National Institutes of Health plans to spend $161.3 million over the next five years to expand the Pharmacogenomics Research Network (PGRN), a nationwide collaborative of scientists focused on understanding how genes affect a person's response to medicines.

"Thanks to breakthroughs in genome sequencing technologies and our growing understanding of genetic variation among individuals, there has never been a better time to propel the field of pharmacogenomics,'' said NIH Director Francis S. Collins, M.D., Ph.D. "Through these studies, we are moving closer to the goal of using genetic information to help prescribe the safest, most effective medicine for each patient."

Spearheaded by the NIH's National Institute of General Medical Sciences (NIGMS) and launched in 2000, the PGRN has already identified gene variants linked to responses to medicines for different cancers, heart disease, asthma, nicotine addiction and other conditions.

The expanded network will continue research in these areas and move into new ones, including rheumatoid arthritis and bipolar disorder. Network scientists will also develop novel research methods and study the use of pharmacogenetics in rural and underserved populations.

The new awards include 14 scientific research projects and seven network resources. The resources will benefit PGRN scientists by:

  • offering deep DNA sequencing capacity by partnering with experts in this field
  • providing statistical analysis expertise
  • developing standardized terminology for pharmacogenomics research
  • piloting ways to learn about pharmacogenomics from de-identified medical records in health care systems
  • continuing and expanding a 2-year-old international collaboration with the Center for Genomic Medicine at the RIKEN Institute in Yokohama, Japan.

Research Groups

The PGRN research group projects are listed below alphabetically by principal investigator.
'/>"/>

Contact: Alisa Zapp Machalek
alisa.machalek@nih.gov
301-496-7301
NIH/National Institute of General Medical Sciences
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. NIH expands key pharmacogenomics resource
2. Core knowledge of tree fruit expands with apple genome sequencing
3. High-resolution imaging expands vision research of live birds of prey
4. Orbel Expands Fabric over Foam Gasket Product Line
5. HIV vaccine strategy expands immune responses
6. Identive Group Expands Executive Management Team
7. Identive Group Expands Executive Management Team
8. Nepal expands critical tiger habitat
9. ID Analytics Expands Availability of On-Demand Identity Intelligence Solutions for the Government Market
10. Fujitsu Expands Support for Ethernet Networks With New Additions to XG Switch Product Line
11. NIH expands Human Microbiome Project; funds sequencing centers and disease projects
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... channels are implicated in many serious conditions such as ... potential target for drug therapies. Unfortunately, there is still ... Cambridge research provides fresh and unexpected insight into the ... components - β-subunit molecules - which are responsible for ... published in the most recent edition of the ...
(Date:4/17/2014)... Researchers reporting in the Cell Press journal Current ... insects with rather novel sex lives. The Brazilian insects, ... genus Neotrogla , are the first example of ... reversal has been identified in several different animals, ... intromittent organ is also reversed," says Kazunori Yoshizawa from ...
(Date:4/17/2014)... whereby the genetic information of DNA is used ... have numerous different functions in living organisms. Messenger ... gene expression, by relating the genetic information of ... proteins. , By examining the different types ... organism at a given time, researchers can determine ...
Breaking Biology News(10 mins):Structure of sodium channels different than previously believed 2In sex-reversed cave insects, females have the penises 2Rapid and accurate mRNA detection in plant tissues 2
... 5,893 leaks from aging natural gas pipelines have been found ... from Duke University and Boston University. A dozen of ... Some manholes had methane concentrations as high as 500,000 parts ... than the threshold at which explosions can occur. ...
... Researchers from the University of Toronto (U of T) have ... claims an individual,s nutritional needs vary by blood type--is not ... One . , "Based on the data of ... ,blood-type, diet theory," said the senior author of the study, ...
... RICHLAND, Wash. -- Researchers simulating how certain bacteria run ... secret Nature uses for electron travel. The results are ... the ground, and will help researchers use them in ... electricity. Within the bacteria,s protein-based wire, molecular groups ...
Cached Biology News:5,900 natural gas leaks discovered under Washington, D.C. 25,900 natural gas leaks discovered under Washington, D.C. 3Popular blood type diet debunked 2Hugging hemes help electrons hop 2Hugging hemes help electrons hop 3Hugging hemes help electrons hop 4
(Date:1/15/2014)... Scottsdale, Arizona (PRWEB) January 15, 2014 ... growth for Scottsdale’s Brain State Technologies®. They saw continued ... University Medical Center who were awarded a $1 million ... papers published in “Brain and Behavior” a peer reviewed ...
(Date:1/15/2014)... 15, 2014 AudioNotch is the internet's ... for the treatment of tinnitus. Patients listen to sound ... over a period of weeks to months, their tinnitus volume ... two forms: Notched Music and Notched White Noise. Now, AudioNotch ...
(Date:1/14/2014)... PA (PRWEB) January 14, 2014 Date: Friday, ... , Location: Warrington Country Club, 1360 Almshouse Road, Warrington, Pa. ... national nonprofit organization solely dedicated to finding a cure for ... affected worldwide, will host its annual Crystal Ball on Friday, ...
(Date:1/14/2014)... San Diego, CA (PRWEB) January 14, 2014 ... based on the products of cells grown under simulated ... an international license agreement with Suneva Medical, Inc. for ... media (CCM). , This agreement is an ...
Breaking Biology Technology:Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3Hepatitis B Foundation to Host Annual Crystal Ball Gala 2Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 2Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 3
... containers at international ports could be the most affordable ... system are not carrying nuclear bombs, according to a ... meeting of the Institute for Operations Research and the ... scheme now in place that relies on targeting only ...
... New Delhi, Singapore and Washington DC (July 27, 2009) ... Medical Decision Making , a large-scale, covert anthrax ... even with an extremely effective public health response, primarily ... initiating a response to it. The article "Predicting ...
... Institute of Technology, collaborating with pediatric cardiologists and ... developed a tool for virtual surgery that allows ... different surgical approaches. By manipulating three-dimensional cardiac magnetic ... can compare how alternative approaches affect blood flow ...
Cached Biology Technology:Study on keeping nuclear bombs from US ports shows misplaced fear over cargo scanning cost 2Study on keeping nuclear bombs from US ports shows misplaced fear over cargo scanning cost 3Study on keeping nuclear bombs from US ports shows misplaced fear over cargo scanning cost 4Bioterrorism and disaster preparedness explored in special issue of Medical Decision Making 2MRI simulation of blood flow helps plan child's delicate heart surgery 2MRI simulation of blood flow helps plan child's delicate heart surgery 3MRI simulation of blood flow helps plan child's delicate heart surgery 4
... plates have low background fluorescence, minimal ... treated (or medium binding) polystyrene surface ... biomolecules through passive interactions,• Is ... large molecules, such as antibodies, that ...
... washer 100-240 V, is used for washing ... V-bottom wells. The immunowash microplate washer has ... to an accuracy of 0.1 mm for ... It can store up to 75 wash ...
... The Model 1575 immunowash microplate washer, ... microplates that have flat-, U-, or V-bottom ... and vertical needle positions to an accuracy ... aspiration, and overflow washing. It can store ...
... a compact benchtop and stackable multi-function ... with a large display screen to ... Air circulation inside to evenly distribute ... be easily calibrated from the microprocessor ...
Biology Products: