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NIH expands Human Microbiome Project; funds sequencing centers and disease projects
Date:6/23/2009

dicine, Baltimore
Vagina: Bacterial Vaginosis
$980,000
This study will assess the vaginal microbiome and whether it contributes to the risk of bacterial vaginosis, a condition where harmful bacteria outgrow healthy bacteria. Bacterial vaginosis is a risk factor for pre-term delivery and sexually transmitted diseases.

Julia Segre, Ph.D., National Human Genome Research Institute, Bethesda, Md.
Skin and nose: Atopic Dermatitis, Immunodeficiency Syndromes
$400,000
The goal of this study is to examine the microbiomes of the skin and nose in three groups of patients with an inflammatory skin disease called atopic dermatitis. Researchers will look for associations between microbiomes, genetic factors associated with atopic dermatitis, and whether patients suffer from immunodeficiency syndromes.

Gregory A. Storch, M.D., Washington University School of Medicine, Saint Louis
Nose, digestive tract and blood: Febrile Illness
$950,000
This team of investigators will examine if there is a relationship between the immune system and viral microbiome of groups of children who are healthy and those who are sick with illnesses that cause a sudden high fever.

Phillip I. Tarr, M.D., Washington University School of Medicine, Saint Louis
Digestive tract: Necrotizing Enterocolitis
$1 million
This group of researchers will examine the potential connection between the intestinal microbiome and the development of necrotizing enterocolitis, a gastrointestinal disorder that can damage the intestine, in premature infants.

James Versalovic, M.D., Ph.D., Baylor College of Medicine, Houston
Digestive tract: Pediatric Irritable Bowel Syndrome (IBS)
$750,000
This project will examine the composition of the intestinal microbiome and any possible connections with irritable bowel syndrome in children.

Gary D. Wu, M.D., University of Pennsylvania School of Medicine, Philadelphia
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Contact: Geoffrey Spencer
spencerg@mail.nih.gov
301-402-0911
NIH/National Human Genome Research Institute
Source:Eurekalert

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