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NIH awards group $4.5 million for smart artificial pancreas technology
Date:10/26/2011

technology a reality."

UCSB is playing the lead role in organizing this international consortium of prominent diabetes researchers, an assembly of world leaders in the fields of computer modeling, control systems, simulation and clinical research. The artificial pancreas research group includes Professor Doyle, Howard Zisser of the Sansum Diabetes Research Institute, Boris Kovatchev of University of Virginia, Ananda Basu of the Mayo Clinic, and Claudio Cobelli of University of Padova, Italy.

In the United States, as many as 3 million people are living with type 1 diabetes, with more than 30,000 youth and adults diagnosed every year. Type 1 diabetes is an autoimmune disease wherein the body's immune system attacks and destroys the insulin-producing cells of the pancreas. For someone with type 1 diabetes, regulating their blood sugar level currently involves a daily regimen of multiple insulin injections or an insulin pump, in addition to blood sugar testing 8 10 times a day.

"Our final goal of an ambulatory artificial pancreas has the potential to make a tremendous impact on the health and lives of people with type 1 diabetes," said Howard Zisser, co-Principal Investigator and Director of Clinical Research at Sansum Diabetes Research Institute.

In recent years, Doyle and Zisser have collaborated to launch the Artificial Pancreas Program at SDRI and UCSB, and have been testing their system in inpatient clinical trials at SDRI. The development of CLC technology has made significant strides over the last five years, but the research consortium understands the challenges faced in gaining FDA approval for an artificial pancreas system.

"The typical research-to-clinical process can be slow because the academic research must be complete and approved before clinical trials can begin," explained Zisser. "Our study will be an example of translational medical research, or research conducted in the lab and safely in a clinical s
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Contact: Melissa Van De Werfhorst
melissa@engineering.ucsb.edu
805-893-4301
University of California - Santa Barbara
Source:Eurekalert  

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