Navigation Links
NIH awards $7.5 million to study MRI as a tool to evaluate children with muscular dystrophy
Date:5/7/2010

Duchenne muscular dystrophy research at the University of Florida got a major boost with the award of $7.5 million in National Institutes of Health funding to study the use of magnetic resonance imaging in determining the natural progression of the disease.

UF scientists will assess whether MRI technology can be used as a precise, noninvasive measure of muscle tissue in children with Duchenne muscular dystrophy. Understanding how the disease affects muscle tissue could help facilitate the testing of new therapies in clinical trials, researchers say.

Duchenne muscular dystrophy affects about one of every 3,500 to 5,000 boys born each year in the United States, according to the Centers for Disease Control and Prevention. The disease causes the muscles that control movement to progressively weaken and lose the ability to regenerate after an injury, eventually replacing critical muscle tissue with fat and collagen. By age 12, many patients need a wheelchair. As the disease advances, the heart and respiratory system are affected and patients often die of cardiorespiratory failure in their 20s.

"The lack of a reliable assessment tool for measuring muscle function in patients with Duchenne inhibits the transfer of new therapies from the lab to clinical trials," said the study's lead investigator KristaVandenborne, Ph.D., an associate dean for research and planning at the UF College of Public Health and Health Professions and chair of the department of physical therapy. "MRI allows you to look at the structure of a muscle tissue in a very objective way with a large amount of detail. Our goal is to develop MRI as a tool to see the progression of the disease, but more importantly, to determine if a new treatment is effective or not, giving researchers rapid feedback about potential new drugs."

The study is funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases and the National Institute of Neurological Diso
'/>"/>

Contact: Jill Pease
jpease@phhp.ufl.edu
352-273-5816
University of Florida
Source:Eurekalert

Page: 1 2

Related biology news :

1. ASNTR meeting presents Sanberg Awards to Prof. Lin & Prof. Dunnett
2. Ames Laboratory scientists win national technology transfer awards
3. Sandia wins 2 national technology transfer awards for work with Cray, Stirling Energy Systems
4. EPA awards more than $1 million to college teams for environmental innovation
5. Autism Speaks awards 16 new research grants funding more than $5 million over next 3 years
6. Washington State Life Sciences Discovery Fund awards health research program grants
7. Ohio Third Frontier awards million-dollar grant to YSI-University of Cincinnati team
8. 2010 Human Frontier Science Program awards announced
9. NYU School of Medicine presents biomedical researchers Dart/NYU Biotechnology Achievement Awards
10. SEBM Distinguished Scientist Awards for 2010
11. AADR awards 2010 Neal W. Chilton Fellowship in Clinical Research to Dolphus Dawson, III
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/23/2014)... soils store four times more carbon than the ... can have a big effect on atmospheric greenhouse ... Nature Climate Change concludes that climate ... or affect soil carbon storage, despite increases in ... U.S. Forest Service Research Ecologist Dr. Christian Giardina, ...
(Date:9/23/2014)... a cyberwar against cancer finds that the immune system ... research has found that cancer is already adept at ... the interplay between cancer and the immune system to ... said Rice University,s Eshel Ben-Jacob, co-author of a new ... Proceedings of the National Academy of Sciences . ...
(Date:9/23/2014)... is essential in the development of animals and plants. ... genetic information be translated in a reliable manner to ... The French-flag model of stripe formation is a classic ... different colours of the French flag, is caused by ... high, middle or low concentrations of the morphogen a ...
Breaking Biology News(10 mins):Study helps assess impact of temperature on belowground soil decomposition 2Immune system is key ally in cyberwar against cancer 2Immune system is key ally in cyberwar against cancer 3Recreating the stripe patterns found in animals by engineering synthetic gene networks 2
... patient, according to a study recently published in PLoS ... and includes bacteria common in the environment, some of ... "This is the first reported case of invasive human ... the article. , The new bacterium ...
... derived human gene trees by Alan R. Templeton, Ph.D, ... major waves of human migration out of Africa instead ... 'Out of Africa' replacement theory. , That theory holds ... ago and wiped out existing populations of humans. ...
... that normally develops when a mouse repeatedly experiences defeat ... gene for a memory molecule in a brain circuit ... of Health's (NIH) National Institute of Mental Health (NIMH) ... molecule continued to welcome strangers in spite of repeated ...
Cached Biology News:Scientists discover a new disease-causing bacterium in an immune-compromised patient 2New analysis shows three human migrations out of Africa 2Mice lacking social memory molecule take bullying in stride 2Mice lacking social memory molecule take bullying in stride 3
(Date:9/23/2014)... 23, 2014 News Facts ... devoted to genome-based research for human health and ... is taking a bite out of oral cancer with its ... India with the help of state-of-the-art ... Networks (DDN). , To fuel its cutting-edge cancer research, ...
(Date:9/23/2014)... , September 23, 2014 ... System Transfer     Devices  (CSTD) for ... with Taiwanese distributor MedFront Medical Technology Corporation.  Equashield,s leading CSTD ... Taiwan , China ... company continues to expand globally, and throughout the ...
(Date:9/23/2014)... The Minnesota High Tech Association (MHTA) ... modems , platforms and application-specific remote monitoring systems, ... the 2014 Tekne Awards. The awards ceremony ... Center on Thursday, November 13th. The Tekne Awards ... superior technology innovation and leadership. , The ...
(Date:9/22/2014)... , September 22, 2014 ... announced the addition of the "Global Biotechnology ...      (Logo: http://photos.prnewswire.com/prnh/20130307/600769) Biotechnology ... added to a system to detect and examine ... are generally used in laboratories to prepare, collect, ...
Breaking Biology Technology:National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 2National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 3National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 4National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 5Equashield Enters Taiwan Following Expansion to Australia, Japan, China 2NimbeLink Named Finalist for 15th Annual Tekne Awards 2NimbeLink Named Finalist for 15th Annual Tekne Awards 3Global Biotechnology Reagents Market 2014-2018: Key Vendors are Agilent, BD Biosciences, Bio-Rad, F. Hoffmann-La Roche, Sigma-Aldrich and Thermo Fisher 2Global Biotechnology Reagents Market 2014-2018: Key Vendors are Agilent, BD Biosciences, Bio-Rad, F. Hoffmann-La Roche, Sigma-Aldrich and Thermo Fisher 3
... the World,s 3rd Largest Biotech Cluster By ... Developing more than 175 Local Companies, SAN ... 30th Anniversary Reunion for Hybritech employees will,take place on Saturday, ... Diego., In September 1978 Hybritech, San Diego,s "Granddaddy" biotech ...
... Inc., (TSX: IXS.V, OTC Bulletin Board: IXSBF, http://www.ixsbio.com ... of monoclonal antibodies based on its Dynamic Cross ... of Directors., Mr. Warden was a founding ... 23 years of practice, he has represented both ...
... Inc. (OTC Bulletin Board: CHBT) (,China-Biotics," "the,Company"), ... manufacture,research, development, marketing and distribution of probiotics ... equipment for its new manufacturing,facility., The ... is,located in Qing Pu Industrial Park (the ...
Cached Biology Technology:San Diego's Original Biotech Company Celebrates 30th Anniversary With Reunion 2InNexus Biotechnology Strengthens Patent Team With New Leadership 2China-Biotics, Inc. Provides Update on Construction of New Manufacturing Facility 2