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NIH awards $6.5 million grant to UT Southwestern to develop new antibiotic
Date:3/25/2008

fe for use in humans, she said.

Dr. Sperandios research has focused on understanding a strain of E. coli known as enterohemorrhagic E. coli 0157:H7, or EHEC. Her research focuses on how bacteria living inside the human body both the helpful ones and the ones that make people sick communicate with one another and with their host. Shes particularly interested in the biochemical signals EHEC uses to cause disease.

A native of Brazil, Dr. Sperandio was named a 2004 Ellison Medical Foundation New Scholar in Global Infectious Disease Research. Through this program, scholars early in their careers received $50,000 annually for five years from the nonprofit foundation to support research in areas that are often underfunded or not funded by traditional sources.

She was also named a 2006 Burroughs Wellcome Fund Investigator in Pathogenesis of Infectious Diseases. Scholars in this program receive $500,000 over five years to study the pathogenesis of infectious diseases typically understudied.

Dr. Sperandios research has also been supported by other grants from the NIH, as well as the Robert A. Welch Foundation and a High Risk/High Impact grant from UT Southwestern.

Other UT Southwestern researchers involved in this research are Dr. Noelle Williams, assistant professor of biochemistry; Dr. Ron Taussig, associate professor of pharmacology; Dr. David Rasko, assistant professor of microbiology; and Dr. John R. Falck, professor of biochemistry and pharmacology. Researchers from Harvard Medical School and Omm Scientific, a privately-held biotech company that manufactures specialty organic chemicals, are also involved.


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Contact: Kristen Holland Shear
kristen.hollandshear@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert  

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