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NIH and NFL tackle concussion research
Date:12/16/2013

e affected by brain injury. Dr. Suskauer and her colleagues will investigate whether somatosensory system information processing (SSIP) could be used as a biomarker for concussion and recovery in youth aged 13-17. For these experiments, the researchers will use a new portable device that delivers vibrations to fingertips. Perception of the vibrations reflects activity of sensory neurons in the brain, thereby providing a measure of SSIP. The researchers will also investigate whether changes in SSIP are related to differences in certain brain chemicals after head injury.

  • Characterization of the Brain and Serum Metabolome in Mouse Models of Concussion
    Principal Investigator: Michael J. Whalen, M.D., Massachusetts General Hospital, Boston

    Metabolites are small molecules formed in the body as a result of the normal breakdown of proteins, drugs and other large molecules. The collection of all metabolites in the body is the metabolome. Studies have suggested that head injury may change levels of various brain byproducts, but this has not been researched in a systematic way. Dr. Whalen and his group plan to use an experimental model of traumatic brain injury to conduct a detailed analysis of changes in the brain metabolome following concussion. The researchers will compare those differences with serum byproducts to determine if the changes can be revealed in blood samples. The results of this project may uncover metabolites that contribute to serious effects of traumatic brain injury and may help identify potential targets for detecting and treating concussions.


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  • Contact: Barbara McMakin
    nindspressteam@ninds.nih.gov
    301-496-5751
    NIH/National Institute of Neurological Disorders and Stroke
    Source:Eurekalert

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