Navigation Links
NIH TRND program announces next round of drug development projects
Date:11/15/2011

at afflicts more than 200 million people worldwide. The disease can cause severe anemia, diarrhea, internal bleeding and/or organ damage. Neglected diseases are conditions that inflict severe health burdens on the world's poorest people. This project aims to produce compounds that retain the positive anti-parasitic effects of the current treatment, praziquantel, which stuns and kills the worms while enabling lower and less frequent doses with potential for improved tolerability. This may allow broader access of a therapeutic to affected patients.

A drug candidate for treatment of Duchenne muscular dystrophy.
Peter Sazani, Ph.D., Executive Director of Preclinical Development
AVI BioPharma, Bothell, Wash.

Duchenne muscular dystrophy is an inherited, rapidly progressive form of muscular dystrophy affecting approximately 1 in 3,500 male births worldwide. This collaboration aims to develop a compound that would treat a sub-group of patients with a specific mutation responsible for Duchenne muscular dystrophy. The team will also investigate the general utility of this innovative treatment platform technology.

A pharmacological therapy for treatment of autoimmune pulmonary alveolar proteinosis.
Bruce C. Trapnell, M.D., Francis R. Luther Professor of Medicine and Pediatrics
Cincinnati Children's Hospital Medical Center-Research Foundation, Cincinnati, Ohio.

Pulmonary alveolar proteinosis is a rare lung disease characterized by the build-up of a grainy material in the air sacs of the lungs that causes breathing difficulties and can result in respiratory failure in rare cases. The protein therapeutic that is the subject of this collaboration will be developed as an inhaled therapy.

TRND has established data-driven milestones for each project to track progress and allow projects which do not achieve milestones in the established timeframe to be terminated, thus allowing other promising candid
'/>"/>

Contact: Geoffrey Spencer
spencerg@mail.nih.gov
301-451-8325
NIH/National Human Genome Research Institute
Source:Eurekalert

Page: 1 2 3 4 5

Related biology news :

1. Researchers develop new self-training gene prediction program for fungi
2. Childrens gardening programs grow environmental stewards
3. Color My Pyramid nutrition education program battles obesity in DC schools
4. Yamanaka eliminates viral vector in stem cell reprogramming
5. Salk researchers successfully reprogram keratinocytes attached to a single hair
6. Evolved Machines Selected as a Prime Contractor for DARPA Program to Engineer an Artificial Olfaction System
7. International Council for Science launches major research program on natural disasters
8. ICSU launches new program to understand the human impact on Earths life-support systems
9. SAIC Awarded $37 Million Contract to Support U.S. Army Program Executive Office - Enterprise Information Systems
10. TECNALIA leads five projects within the VII Framework Program
11. NWO and Academy launch research program with China
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/14/2014)... new study published in Cancer Research shows ... and colon cancers—can promote the development of skin cancers ... and survival of sun-damaged skin cells. , Previously considered ... proteins called sirtuins that help regulate genomic stability and ... SIRT6 helps repair DNA damage, which can lead to ...
(Date:10/14/2014)... a new kind of stem cell that can become either ... vessels, according to a study published today in the journal ... cell type contradicts current theory on how organs arise from ... origins of, and future treatment for, liver cancer., Thanks to ... complex being made up of more than 200 cell types. ...
(Date:10/14/2014)... team of researchers, led by the Chinese Academy of ... Nature Genetics a brief genomic history of tomato ... tomato plant. , The C.M. Rick Tomato Genetics Resource ... this study by providing seed of both cultivated tomato ... builds on the first tomato genome sequence completed just ...
Breaking Biology News(10 mins):Two-faced gene: SIRT6 prevents some cancers but promotes sun-induced skin cancer 2Stem cell discovery challenges dogma on how fetus develops; holds insights for liver cancer and reg 2Stem cell discovery challenges dogma on how fetus develops; holds insights for liver cancer and reg 3
... a half-dozen palladium- and iron-based catalysts for cleaning up the ... TCE far faster than iron -- up to a billion ... in a new study in the August issue of the ... trichloroethene, is a widely used chemical degreaser and solvent that,s ...
... Six, the world leader in synthetic diamond supermaterials, ... Departments of Chemistry and Physics, have demonstrated the ... metal-like boron-doped synthetic diamond. The research shows that ... retaining the full strength and durability of its ...
... NANG, VietnamU.S. scientists and Vietnamese researchers will discuss coastal ... the R/V Roger Revelle , an auxiliary general ... port call in the city of Da Nang. ... operated by the Scripps Institution of Oceanography, the advanced ...
Cached Biology News:Palladium-gold nanoparticles clean TCE a billion times faster than iron filings 2Synthetic diamond steps closer to next generation of high performance electrochemical applications 2Synthetic diamond steps closer to next generation of high performance electrochemical applications 3US research vessel winds down visit to Vietnam as part of joint oceanographic research program 2
(Date:10/19/2014)... Asian Orthopedic braces and support systems report defines and segments ... revenue. The Orthopedic braces and support systems market in Asia ... at a developing CAGR of 4.4% from 2013 to 2018. ... and support systems market, to get an idea of the ... segmentation of orthopedic braces and support systems market in the ...
(Date:10/18/2014)... 2014 The report "1,6-Hexanediol Market ... Forecasts to 2019", analyzes the global market on ... understand the industry details such as the key ... geographic regions. , Browse 81 Market Data Tables ... in-depth TOC on “1,6-Hexanediol Market by Application and ...
(Date:10/18/2014)... 18, 2014 The Biomass Power ... the five years to 2014. The industry's expansion has ... tax credits that encouraged the use of biomass power. ... standards (RPSs), which require local utilities to generate electricity ... energy portfolio. Increased campaigning for green technology also influenced ...
(Date:10/17/2014)... WASHINGTON, Oct. 16—As in Alice,s journey through the looking-glass ... behave in surprising and unexpected ways, including a new ... , As reported today in The Optical Society,s (OSA) ... have demonstrated, for the first time, a new type ... and instead reflects infrared light by using an unusual ...
Breaking Biology Technology:The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 2The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 3The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 41,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 21,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 31,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 41,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 5Biomass Power in the US Industry Market Research Report from IBISWorld Has Been Updated 2Biomass Power in the US Industry Market Research Report from IBISWorld Has Been Updated 3Magnetic mirrors enable new technologies by reflecting light in uncanny ways 2Magnetic mirrors enable new technologies by reflecting light in uncanny ways 3Magnetic mirrors enable new technologies by reflecting light in uncanny ways 4
... in three short months! The major stock indices looked pretty ... up steam in the second quarter with the Dow Jones ... eight percent growth for the first half. Not far behind was ... the first quarter and 7% growth for the half year. , ...
... controversy over its proposed overhaul of the state's healthcare system ... pare back additional funding for the Act 255 tax credit ... Joint Committee on Finance. , ,The caucus voted to delete ... investment and early-stage seed investment tax credits. , ,According ...
... CEOs caught up in the scandals of WorldCom, ENRON, and TYCO ... Grigsby . The people on this video make them look like ... for people trying to make a living to support their families. ... in the last couple of years that have not been able ...
Cached Biology Technology:Midwest life science stocks kept sizzling in Q2 2Midwest life science stocks kept sizzling in Q2 3Midwest life science stocks kept sizzling in Q2 4Midwest life science stocks kept sizzling in Q2 5Midwest life science stocks kept sizzling in Q2 6Senate Democrats strip additional Act 255 funding from budget 2A disgusting video: U.S. companies sell out Americans 2A disgusting video: U.S. companies sell out Americans 3A disgusting video: U.S. companies sell out Americans 4
... timer, SB3, Fully adjustable mixing angle, Variable ... to hold a number of different sized ... for aerating cultures, keeping biological samples in ... rotator can be used in incubators up ...
...
Fingerprinting II database sharing tools is an optional module for the Fingerprinting II Basic software package that enables peer-to-peer data exchange over the internet and provides external databas...
Fingerprinting II cluster analysis is an optional module that adds dendrogram and phylogenetic tree construction, cluster and group significance, and congruence of techniques functions to the Fingerp...
Biology Products: