Navigation Links
NIH TRND program announces next round of drug development projects
Date:11/15/2011

g principal investigators are:

An inhibitor compound for treatment of fibrodysplasia ossificans progressiva.
Kenneth D. Bloch, M.D., William T. G. Morton Professor of Anesthesia
Harvard Medical School, Massachusetts General Hospital, Boston.

Fibrodysplasia ossificans progressiva is a rare inherited disorder where muscle and connective tissue such as tendons and ligaments are gradually replaced by bone. The compound under development has shown efficacy in a mouse disease model.

Novel therapy for treatment of creatine transporter deficiency.
Rick Hawkins, Chief Executive Officer
Lumos Pharma, Inc., Austin, Texas.

Creatine transporter deficiency occurs from a mutation in a creatine transporter gene that prevents the transport of sufficient levels of creatine to the brain and results in cognitive function disorder. The lead compound has been evaluated in mice with creatine transporter deficiency and resulted in improved brain metabolism and cognitive function.

A compound for treatment of neonatal herpes simplex virus.
David W. Kimberlin, M.D., Professor of Pediatrics
The University of Alabama at Birmingham.

Neonatal herpes simplex virus is an infection transmitted from mother to child during childbirth. In preliminary studies, the candidate compound that will be advanced by this group shows anti-herpetic activity and can penetrate the central nervous system. This compound has received longstanding development support by National Institute of Allergy and Infectious Diseases, including funding of the current clinical trial that will collaborate closely with TRND.

Development of a deuterium-modified compound for treatment of Schistosomiasis.
Julie F. Liu, Ph.D., Director, Research Management
CoNCERT Pharmaceuticals Inc., Lexington, Mass.

Schistosomiasis is a neglected tropical disease caused by parasitic Schistosoma worms th
'/>"/>

Contact: Geoffrey Spencer
spencerg@mail.nih.gov
301-451-8325
NIH/National Human Genome Research Institute
Source:Eurekalert

0

GOOD

Page: 1 2 3 4 5

Related biology news :

1. Researchers develop new self-training gene prediction program for fungi
2. Childrens gardening programs grow environmental stewards
3. Color My Pyramid nutrition education program battles obesity in DC schools
4. Yamanaka eliminates viral vector in stem cell reprogramming
5. Salk researchers successfully reprogram keratinocytes attached to a single hair
6. Evolved Machines Selected as a Prime Contractor for DARPA Program to Engineer an Artificial Olfaction System
7. International Council for Science launches major research program on natural disasters
8. ICSU launches new program to understand the human impact on Earths life-support systems
9. SAIC Awarded $37 Million Contract to Support U.S. Army Program Executive Office - Enterprise Information Systems
10. TECNALIA leads five projects within the VII Framework Program
11. NWO and Academy launch research program with China
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/16/2013)... of us don,t ponder our pulses outside of the gym. ... to monitor heart health. , Zhenan Bao, a professor of ... than a dollar bill and no wider than a postage ... on the wrist, is sensitive enough to help doctors detect ... day be used to continuously track heart health and provide ...
(Date:5/16/2013)... Germany , May 16, 2013 ... Value Enhancement Award on Tuesday to Germany,s ... its exceptional biometric border control system. DERMALOG ... with the Best Practices Award in the category Global ... its cutting edge Biometric   Border Control System ...
(Date:5/15/2013)... "keystone" molecules that have powerful behavioral effects on ... in structuring ecosystems, according to a theory proposed ... The authors of the theory, Ryan P. Ferrer ... of the University of California at Los Angeles, ... plants that may be uncommon but exert a ...
Breaking Biology News(10 mins):Stanford engineers monitor heart health using paper-thin flexible 'skin' 2Stanford engineers monitor heart health using paper-thin flexible 'skin' 3Global Biometrics and Border Control Award for DERMALOG 2Global Biometrics and Border Control Award for DERMALOG 3Global Biometrics and Border Control Award for DERMALOG 4Natural 'keystone molecules' punch over their weight in ecosystems 2
... Genomics Browser developed by researchers at the University of ... and analyze data from studies aimed at improving cancer ... disease. The browser consists of a suite ... in the huge amounts of clinical and genomic data ...
... toads are far more susceptible to being killed and eaten ... in the British Ecological Society,s journal Functional Ecology ... could help control the spread of this alien invasive species ... Georgia Ward-Fear, Matt Greenlees and Greg Brown from the University ...
... organisms with no nervous system or brain. So how ... complex community called a biofilm "decide" between different physiological ... forms the biofilm)? In the prestigious 2009 ... meeting in Harrogate, (Monday 30 March) Dr Nicola Stanley-Wall ...
Cached Biology News:Cancer Genomics Browser gives cancer researchers a powerful new tool 2Cancer Genomics Browser gives cancer researchers a powerful new tool 3Cancer Genomics Browser gives cancer researchers a powerful new tool 4Aussie meat ants may be invasive cane toad's Achilles' heel 2
(Date:5/17/2013)... -- Insero Health, Inc., a company developing natural compounds to ... disorders, is today reporting top-line results from a Phase ... with drug-resistant epilepsy.  The data are being presented at ... by Dr. Steven Schachter , Harvard ... Board.  In this study, INS001 appeared safe and well ...
(Date:5/17/2013)... The paradigm of ‘one drug, one target’ has ... predict the adverse and therapeutic effects of a drug. ... Biology at the Genomics Laboratory, Covance, will discuss the ... when used as part of the QC process. Additionally, ... to identify key clinical targets even in complex data ...
(Date:5/17/2013)... Rust removal is one of home maintenance's essential ... be damaged. To help rust contractors make it less expensive, ... rust remover it called Rusterizer. It announced that for ... , My Cleaning Products explained that rust could damage items ... them. The first one, it said, happens when rust ...
(Date:5/17/2013)... 17, 2013 Tooth decay is an epidemic ... signs of the disease. The World Health Organization says that ... of adults have cavities. What are the long-term effects of ... a strong connection between the oral bacterial imbalance and serious ... so rampant, yet it is also 100% preventable? Answer: there ...
Breaking Biology Technology:Insero Health Reports Positive Data on Phase I Trial of Novel Therapy for Drug-resistant Epilepsy 2Organic-Based Rust Remover Cuts Down Price by 10%, My Cleaning Products Details Mechanics How to Get the Discount 2Seeing the Future: How a Revolutionary New Bacterial Screening Device Can Predict a Patient’s Future for Tooth Decay 2Seeing the Future: How a Revolutionary New Bacterial Screening Device Can Predict a Patient’s Future for Tooth Decay 3
... , PHOENIX and SAN CARLOS, Calif., Oct. 10 ... data today from its Phase 2 clinical trial of ... (AAPM) 20th Annual Clinical Meeting in Phoenix, Arizona. ... stage investigational product candidate in clinical development for the ...
... developing new sensors to detect chemical agents and illegal drugs ... terrorist attacks. The devices will use special gel pads ... sample which is then analysed by a scanning instrument that ... allow better, faster decisions to be made in response to ...
... N.C. The natural cycle of building bone to maintain ... calcium needs is delicately balanced, but diseases like osteoporosis break ... bone fractures. The results from a new study ... be able to fight osteoporosis and other degenerative bone diseases. ...
Cached Biology Technology:Topline Results from Phase 2 Clinical Trial of Oral NKTR-118 Presented at 20th American Academy of Pain Management Annual Clinical Meeting (AAPM) in Phoenix 2Topline Results from Phase 2 Clinical Trial of Oral NKTR-118 Presented at 20th American Academy of Pain Management Annual Clinical Meeting (AAPM) in Phoenix 3Topline Results from Phase 2 Clinical Trial of Oral NKTR-118 Presented at 20th American Academy of Pain Management Annual Clinical Meeting (AAPM) in Phoenix 4New technology detects chemical weapons in seconds 2New approach for growing bone comes from Duke preclinical research 2
... 5 gasket slides/kit Gasket slide kit (1x ... or Gasket slide ... of disposable gasket slides offered in either 11K or ... formats. The gaskets are carefully fabricated and batch ...
... General description: self locking design ... is a new product number, created ... If showing no availability yet, please ... (Z71,348-1) or contact customer service for ...
... The Arabidopsis 2 Oligo Microarray Kit (V2), 22K ... stages, and stress response. Each microarray contains content ... The Institute for Genomic Research (TIGR) and represents ... 5 standard 1 x 3? glass slides ...
... costs of poor quality running into ... organizations are under increasing pressure to ... production, the microscopic distribution of ingredients ... parameters such as dissolution, stability, bio-availability ...
Biology Products: