Navigation Links
NIH EUREKA grant awarded to University of Miami scientist
Date:9/16/2008

CORAL GABLES, FL (September 16, 2008)- A team of scientists headed by neuroscientist Dr. Akira Chiba has been awarded the first ever EUREKA grant by the National Institute of Health (NIH), to develop a technique that can lead to a new treatment for spinal cord injury. Dr. Chiba, a professor at the University of Miami's Department of Biology, and his collaborators plan to use a novel and groundbreaking process to enhance synapse formation or nerve regeneration.

Dr. Chiba's project focuses on developing nerve connectivity by applying tension to individual neurons. A collaborative work between Dr. Chiba and scientists at the University of Illinois yielded evidence that a mechanical force applied to nascent nerve synapses, or injured embryonic nerve cells initiates, enhances and repairs their connectivity.

"This FORCE (force orchestrated retrograde synaptic enhancement) mechanism is likely based on a property of cells conserved through evolution and, thus, has the potential to be applied widely, including in the field of regenerative medicine," said Chiba. "A Holy Grail of regenerative neuromedicine is spinal cord repair," he said. "It would be rash to predict that our project will solve the problem, but perhaps we can make a significant contribution to the solution."

The project is a multi-disciplinary effort that combines genetics, bioengineering, computational bioinformatics and nanotechnology. If successful, the research will introduce a new concept in the regeneration of central nervous system neurons after injury.

Dr. Chiba's study is one of 38 research projects that will be funded by the $42.2 million grant. Each will receive direct costs of approximately $200,000 per year for up to four years, in support of projects that could have an extraordinary influence on many areas of science.

"The EUREKA Program is a new effort from the National Institutes of Health specifically for exceptionally innovative projects that could have a major impact on biomedical research," said Edmund M. Talley, Ph.D., program director for the National Institute of Neurological Disorders and Strokes. "In the case of Dr.Chiba's team, if they are able to prove the importance of mechanical force in re-growing connections between neurons, and if they are able to determine the molecular events underlying this phenomenon, it could change our understanding of how brain injuries might be repaired," he said.

"Even though it would be just one piece in a giant puzzle, it could be key to developing therapies that would enhance the lives of millions of people worldwide."


'/>"/>

Contact: Marie Guma-Diaz
m.gumadiaz@umiami.edu
305-284-1601
University of Miami
Source:Eurekalert

Related biology news :

1. NYU Cancer Institute researcher among first NIH EUREKA award recipients
2. NIH EUREKA award funds research at WPI aimed at turning adult skin cells into stem-like cells
3. C. Erec Stebbins awarded prestigious EUREKA grant
4. Burnham researcher awarded $8 million grant
5. NSF awards two grants to Stevens for nano/micro device fabrication and nano sensor development
6. UT Knoxville wins 2 $3M National Science Foundation research and education grants
7. NYU receives $490k NSF grant to promote women in the sciences
8. Iowa State wins $18.5M grant to create NSF Center for Biorenewable Chemicals
9. Cornell gets $10 million NSF grant to establish new sustainability institute
10. NYU, American Museum of Natural History receive $1.6 million NSF grant
11. Broad Institute awarded grant to develop chemical probes for human biology and disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2016)... patient care by providing unparalleled technology to leaders of the medical imaging industry.  As ... added to the range of products distributed by Ampronix. Photo - ... ... ... ...
(Date:5/9/2016)... , UAE, May 9, 2016 ... it comes to expanding freedom for high net worth ... Even in today,s globally connected world, there is still ... system could ever duplicate sealing your deal with a ... second passports by taking advantage of citizenship via investment ...
(Date:4/26/2016)... India and LONDON ... Infosys Finacle, part of EdgeVerve Systems, a product ... and Onegini today announced a partnership to integrate ... solutions.      (Logo: http://photos.prnewswire.com/prnh/20151104/283829LOGO ... to provide their customers enhanced security to access ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... June 23, 2016 Houston Methodist Willowbrook ... Cy-Fair Sports Association to serve as their official ... Houston Methodist Willowbrook will provide sponsorship support, athletic ... with association coaches, volunteers, athletes and families. ... Cy-Fair Sports Association and to bring Houston Methodist ...
(Date:6/23/2016)... -- The Biodesign Challenge (BDC), a university competition that asks ... systems and biotechnology, announced its winning teams at the ... York City . The teams, chosen ... MoMA,s Celeste Bartos Theater during the daylong summit. Keynote ... of architecture and design, and Suzanne Lee , ...
(Date:6/23/2016)... ... June 23, 2016 , ... STACS DNA Inc., the sample ... the Arkansas State Crime Laboratory, has joined STACS DNA as a Field Application Specialist. ... said Jocelyn Tremblay, President and COO of STACS DNA. “In further expanding our capacity ...
(Date:6/23/2016)... 23, 2016  Blueprint Bio, a company dedicated to ... medical community, has closed its Series A funding round, ... "We have received a commitment from Forentis ... need to meet our current goals," stated Matthew ... runway to complete validation on the current projects in ...
Breaking Biology Technology: