Navigation Links
NIH EUREKA grant awarded to University of Miami scientist
Date:9/16/2008

CORAL GABLES, FL (September 16, 2008)- A team of scientists headed by neuroscientist Dr. Akira Chiba has been awarded the first ever EUREKA grant by the National Institute of Health (NIH), to develop a technique that can lead to a new treatment for spinal cord injury. Dr. Chiba, a professor at the University of Miami's Department of Biology, and his collaborators plan to use a novel and groundbreaking process to enhance synapse formation or nerve regeneration.

Dr. Chiba's project focuses on developing nerve connectivity by applying tension to individual neurons. A collaborative work between Dr. Chiba and scientists at the University of Illinois yielded evidence that a mechanical force applied to nascent nerve synapses, or injured embryonic nerve cells initiates, enhances and repairs their connectivity.

"This FORCE (force orchestrated retrograde synaptic enhancement) mechanism is likely based on a property of cells conserved through evolution and, thus, has the potential to be applied widely, including in the field of regenerative medicine," said Chiba. "A Holy Grail of regenerative neuromedicine is spinal cord repair," he said. "It would be rash to predict that our project will solve the problem, but perhaps we can make a significant contribution to the solution."

The project is a multi-disciplinary effort that combines genetics, bioengineering, computational bioinformatics and nanotechnology. If successful, the research will introduce a new concept in the regeneration of central nervous system neurons after injury.

Dr. Chiba's study is one of 38 research projects that will be funded by the $42.2 million grant. Each will receive direct costs of approximately $200,000 per year for up to four years, in support of projects that could have an extraordinary influence on many areas of science.

"The EUREKA Program is a new effort from the National Institutes of Health specifically for exceptionally innovative projects that could have a major impact on biomedical research," said Edmund M. Talley, Ph.D., program director for the National Institute of Neurological Disorders and Strokes. "In the case of Dr.Chiba's team, if they are able to prove the importance of mechanical force in re-growing connections between neurons, and if they are able to determine the molecular events underlying this phenomenon, it could change our understanding of how brain injuries might be repaired," he said.

"Even though it would be just one piece in a giant puzzle, it could be key to developing therapies that would enhance the lives of millions of people worldwide."


'/>"/>

Contact: Marie Guma-Diaz
m.gumadiaz@umiami.edu
305-284-1601
University of Miami
Source:Eurekalert

Related biology news :

1. NYU Cancer Institute researcher among first NIH EUREKA award recipients
2. NIH EUREKA award funds research at WPI aimed at turning adult skin cells into stem-like cells
3. C. Erec Stebbins awarded prestigious EUREKA grant
4. Burnham researcher awarded $8 million grant
5. NSF awards two grants to Stevens for nano/micro device fabrication and nano sensor development
6. UT Knoxville wins 2 $3M National Science Foundation research and education grants
7. NYU receives $490k NSF grant to promote women in the sciences
8. Iowa State wins $18.5M grant to create NSF Center for Biorenewable Chemicals
9. Cornell gets $10 million NSF grant to establish new sustainability institute
10. NYU, American Museum of Natural History receive $1.6 million NSF grant
11. Broad Institute awarded grant to develop chemical probes for human biology and disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/11/2016)... -- --> --> ... Market by Technology (Pattern Recognition), by Component (Hardware, Software, ... (On-Premises and Cloud), by Industry Vertical and by Region ... global market is expected to grow from USD 12.49 ... at a CAGR of 19.1%. , ...
(Date:3/9/2016)... NEW YORK , March 9, 2016 ... current and future states of the RNA Sequencing (RNA ... in segments such as instruments, tools and reagents, data ... Analyze various segments of the RNA-Sequencing market such ... RNA-Sequencing services Identify the main factors affecting each segment ...
(Date:3/8/2016)... , March 8, 2016   Valencell ... technology, today announced it has secured $11M in ... GII Tech, a new venture fund being launched ... additional participation from existing investors TDF Ventures and ... funds to continue its triple-digit growth and accelerate ...
Breaking Biology News(10 mins):
(Date:5/25/2016)... LAKE CITY, UTAH. (PRWEB) , ... May 25, 2016 , ... ... efficiencies in healthcare information exchange, today announced that Charles W. Stellar has been named ... as WEDI’s interim CEO since January 2016. As an executive leader with more than ...
(Date:5/25/2016)... ... May 25, 2016 , ... Biohaven Pharmaceutical Holding Company Ltd. ... the company’s orphan drug designation request covering BHV-4157 for the treatment of Spinocerebellar ... FDA. , Spinocerebellar ataxia is a rare, debilitating neurodegenerative disorder that is ...
(Date:5/24/2016)... --  MedyMatch Technology Ltd ., the data analytics healthcare company ... tools in the emergency room, announced today that it has ... Industries (IATI) BioMed Conference. The Conference is ... Life Sciences and Technology Week, and is being held May ... Tel Aviv, Israel . Gene Saragnese , ...
(Date:5/24/2016)... , ... May 24, 2016 , ... ... newly re-branded identity. The new Media Cybernetics corporate branding reflects a results-driven revitalization ... imaging and image analysis. The re-branding components include a crisp, refreshed logo and ...
Breaking Biology Technology: