Navigation Links
NIH EUREKA grant awarded to University of Miami scientist
Date:9/16/2008

CORAL GABLES, FL (September 16, 2008)- A team of scientists headed by neuroscientist Dr. Akira Chiba has been awarded the first ever EUREKA grant by the National Institute of Health (NIH), to develop a technique that can lead to a new treatment for spinal cord injury. Dr. Chiba, a professor at the University of Miami's Department of Biology, and his collaborators plan to use a novel and groundbreaking process to enhance synapse formation or nerve regeneration.

Dr. Chiba's project focuses on developing nerve connectivity by applying tension to individual neurons. A collaborative work between Dr. Chiba and scientists at the University of Illinois yielded evidence that a mechanical force applied to nascent nerve synapses, or injured embryonic nerve cells initiates, enhances and repairs their connectivity.

"This FORCE (force orchestrated retrograde synaptic enhancement) mechanism is likely based on a property of cells conserved through evolution and, thus, has the potential to be applied widely, including in the field of regenerative medicine," said Chiba. "A Holy Grail of regenerative neuromedicine is spinal cord repair," he said. "It would be rash to predict that our project will solve the problem, but perhaps we can make a significant contribution to the solution."

The project is a multi-disciplinary effort that combines genetics, bioengineering, computational bioinformatics and nanotechnology. If successful, the research will introduce a new concept in the regeneration of central nervous system neurons after injury.

Dr. Chiba's study is one of 38 research projects that will be funded by the $42.2 million grant. Each will receive direct costs of approximately $200,000 per year for up to four years, in support of projects that could have an extraordinary influence on many areas of science.

"The EUREKA Program is a new effort from the National Institutes of Health specifically for exceptionally innovative projects that could have a major impact on biomedical research," said Edmund M. Talley, Ph.D., program director for the National Institute of Neurological Disorders and Strokes. "In the case of Dr.Chiba's team, if they are able to prove the importance of mechanical force in re-growing connections between neurons, and if they are able to determine the molecular events underlying this phenomenon, it could change our understanding of how brain injuries might be repaired," he said.

"Even though it would be just one piece in a giant puzzle, it could be key to developing therapies that would enhance the lives of millions of people worldwide."


'/>"/>

Contact: Marie Guma-Diaz
m.gumadiaz@umiami.edu
305-284-1601
University of Miami
Source:Eurekalert

Related biology news :

1. NYU Cancer Institute researcher among first NIH EUREKA award recipients
2. NIH EUREKA award funds research at WPI aimed at turning adult skin cells into stem-like cells
3. C. Erec Stebbins awarded prestigious EUREKA grant
4. Burnham researcher awarded $8 million grant
5. NSF awards two grants to Stevens for nano/micro device fabrication and nano sensor development
6. UT Knoxville wins 2 $3M National Science Foundation research and education grants
7. NYU receives $490k NSF grant to promote women in the sciences
8. Iowa State wins $18.5M grant to create NSF Center for Biorenewable Chemicals
9. Cornell gets $10 million NSF grant to establish new sustainability institute
10. NYU, American Museum of Natural History receive $1.6 million NSF grant
11. Broad Institute awarded grant to develop chemical probes for human biology and disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/20/2017)... (NYSE: DAL ) customers now can use fingerprints instead of ... Airport (DCA). ... Delta launches biometrics to board aircraft at Reagan Washington National Airport ... Delta,s biometric boarding pass experience that launched in May ... boarding process to allow eligible Delta SkyMiles Members who are enrolled in ...
(Date:5/16/2017)...  Veratad Technologies, LLC ( www.veratad.com ), an innovative ... verification solutions, announced today they will participate as a ... thru May 17, 2017, in Washington D.C.,s ... Identity impacts the lives of billions ... evolving digital world, defining identity is critical to nearly ...
(Date:4/18/2017)... 2017  Socionext Inc., a global expert in SoC-based imaging and ... the M820, which features the company,s hybrid codec technology. A demonstration ... Probe, Inc., will be showcased during the upcoming Medtec Japan at ... the Las Vegas Convention Center April 24-27. ... Click here for an ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... 12, 2017 , ... They call it the “hairy ball.” ... depiction of a system of linkages and connections so complex and dense that ... computer science at Worcester Polytechnic Institute (WPI) and director of the university’s bioinformatics ...
(Date:10/12/2017)... ... October 12, 2017 , ... RPS ... clinical study that demonstrates the accuracy of the FebriDx® test, a commercially-ready, ... acute bacterial and viral respiratory tract infections by testing the body’s immune ...
(Date:10/12/2017)... , ... October 12, 2017 ... ... has launched Rosalind™, the first-ever genomics analysis platform specifically designed for life ... Named in honor of pioneering researcher Rosalind Franklin, who made a major ...
(Date:10/11/2017)... ... 11, 2017 , ... Personal eye wash is a basic first aid supply for any work ... which eye do you rinse first if a dangerous substance enters both eyes? It’s one ... with its unique dual eye piece. , “Whether its dirt and debris, or an ...
Breaking Biology Technology: