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NIH Director's Awards go to 3 Johns Hopkins scientists
Date:9/20/2011

virus that causes AIDS, leading to some half-million deaths annually among those co-infected.

As the director of CAAT, Transformative Research Projects Award recipient Thomas Hartung received the funding for a consortium to develop a new technological methodology for mapping the molecular pathways of toxicity within cells. CAAT's ambitious goal is a comprehensive understanding of molecular "pathways of toxicity (PoT)" that lead to adverse health effects when perturbed. "Mapping the entirety of these pathwayswhich I've termed the 'Human Toxome'will be a large-scale effort, perhaps on the order of the Human Genome Project," Hartung says.

As a first step to mapping the Human Toxome, Hartung and his collaborators have proposed tackling the pathways of endocrine disruption, a perturbation of the hormonal system that can cause tumors, birth defects, and developmental disorders.


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Contact: Maryalice Yakutchik
myakutc1@jhmi.edu
443-287-2251
Johns Hopkins Medical Institutions
Source:Eurekalert

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