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NIGMS invests in scientific Grand Opportunities with Recovery Act funds

er-based system to help doctors tailor their prescriptions to the genetic profile of each patient. The project aims to improve the effectiveness and safety of drug therapies.

  • Gene Expression and Regulatory Networks in Human Leukocytes, $7.3 million.
    Christophe Benoist and Diane Mathis, Harvard Medical School, Boston

  • Advancing Drug Development from Medicinal Plants using Transcriptomics and Metabolomics, $6 million.
    Joseph Chappell, University of Kentucky, Lexington
    Dean Dellapenna, Michigan State University, East Lansing
    Sarah O'Connor, Massachusetts Institute of Technology, Cambridge

  • The Cell: An Image Library, $2.5 million.
    Caroline Kane, American Society for Cell Biology, Bethesda, Md.

  • Fine-scale Recombination Rate Variation Within and Between Drosophila Species, $1.8 million.
    Josep Comeron, University of Iowa, Iowa City
    Corbin Jones, University of North Carolina at Chapel Hill
    Mohamed Noor, Duke University, Durham, N.C.

  • ImageJ as an Extensible Image Processing Framework, $1.8 million.
    Kevin Eliceiri, University of Wisconsin-Madison

  • Subcellular Localization of Nanoparticles, $3 million.
    Mauro Ferrari, Paolo Decuzzi and David Gorenstein, University of Texas Health Science Center, Houston
    Jim Klostergaard, Gabriel Lopez-Berestein, Chun Li and Anil Sood, University of Texas M.D. Anderson Cancer Center, Houston
    Rebekah Drezek, Jennifer West, Lon Wilson and Junghae Suh, Rice University, Houston, Texas
    Wah Chiu, Baylor College of Medicine, Houston, Texas

  • Metabolomics Network for Drug Response Phenotype, $4.5 million.
    Rima Kaddurah-Daouk, Duke University Medical Center, Durham, N.C.

  • The Arabidopsis Transcription Factor ORFeome + Downstream Genomic Application, $2 million.
    Steve Kay, University of California, San Diego
    Joseph Ecker, Salk Institute for Biological Studies, La Jolla, Calif.

  • Contact: Alisa Machalek
    NIH/National Institute of General Medical Sciences

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