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NIAID funds studies of how SARS and bird flu evade antiviral responses
Date:10/16/2008

living things. The UW research program is unusual in that, in addition to the traditional simple cell culture models, it will also use mouse and nonhuman primate infection models. These animal models will allow researchers to study disease-relevant complexities, Such information is likely to help translate findings into new clinical initiatives, including new targets for therapeutic intervention. Understanding the initial, innate, antiviral response also has potential in developing alternative vaccine strategies, where such early signals are exploited to induce more robust adaptive immune outcomes.

"This program is distinctive in its comparison of different respiratory viruses and the incorporation of animal models," said Katze. "There are few antiviral drugs available and none that work against diverse types of viruses. It would be extremely beneficial to have information that could lead to the rational design of a drug that could be used against a range of different viruses."


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Contact: Leila Gray
leilag@u.washington.edu
206-685-0381
University of Washington
Source:Eurekalert

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