Navigation Links
NIA uses Genomatix in stem cell research, suggests novel transcription factors for stemness
Date:3/3/2008

Genomatix Software with businesses in Munich, Germany and Ann Arbor, Michigan released today that the group of Kenneth R. Boheler at the National Institute on Aging, National Institutes of Health, Baltimore, Md published some remarkable work on embryonic stem (ES) cells.

In their work they first identified and validated ES cell predominant transcripts by SAGE and qRT-PCR methods. Then they employed extensive DNA promoter analysis based on the integrated Genomatix system in order to identify conserved cis-elements and putative trans-regulators. Framework analysis for promoter organization, as introduced by Genomatix, increased likeliness for functional significance of the candidate transcription factors. Predictions were experimentally verified by Chromosomal Immunoprecipitation assays.

The study led to the novel identification of two transcription factors, B-Myb and Maz which are implicated either in the maintenance of the undifferentiated stem cell state or in early steps of differentiation.


'/>"/>

Contact: Klaus May
may@genomatix.de
49-895-997-660
Genomatix Software GmbH
Source:Eurekalert

22

GOOD

Page: 1

Related biology news :

1. Computer-based tool aids research, helps thwart questionable publication practices
2. Widespread support for nonembryonic stem cell research, VCU Life Sciences Survey shows
3. New research suggests biofuel blending is often inaccurate
4. Study suggests genetic connection between short stature and arthritis
5. Deep-sea species loss could lead to oceans collapse, study suggests
6. BMI criteria for obesity surgery should be lowered, UT Southwestern researcher suggests
7. Study suggests link between obesity, poor bone health
8. Yale discovery suggests protein may play a role in severe asthma
9. Wasp genetics study suggests altruism evolved from maternal behavior
10. Misconceptions about Alzheimers varies among races, survey suggests
11. Feeling hot, hot, hot: New study suggests ways to control fever-induced seizures
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... honored more than 165 staff for their creation, ... annual Intellectual Property Commercialization Recognition & Rewards Program ... laboratory named materials scientist Jun Liu Inventor of ... that can store large amounts of energy, ease ... time it takes to charge cell phones, electric ...
(Date:5/23/2013)... than 13,000 ships per year, carrying more than 284 million ... roughly $1.8 billion dollars in toll fees for the Panama ... 55 million gallons of water are used from Gatun Lake, ... million people living in the isthmus. , However, the ... 20 percent of the ships at sea, has demanded change. ...
(Date:5/23/2013)... of Public Health at Emory University, along with ... received a $4 million grant over four years ... (Health and Exposome Research Center: Understanding Lifetime Exposures). ... awarded in the United States. , The ... of Environmental Health Sciences (NIEHS) of the National ...
Breaking Biology News(10 mins):PNNL staff recognized for scientific accomplishments, moving technologies into the marketplace 2Reforestation study shows trade-offs between water, carbon and timber 2Reforestation study shows trade-offs between water, carbon and timber 3Emory, Georgia Tech receive first human exposome center grant in US 2Emory, Georgia Tech receive first human exposome center grant in US 3
... 8, 2009) Van Andel Research Institute ... an important therapeutic target in the treatment of the ... these cancers have few treatment options. "Breast cancer ... don,t respond to traditional treatments tend to be more ...
... self-organizing systems are the Holy Grails of nanotechnology, but ... years. A team of scientists has taken a unique ... able to assemble into clusters that direct cell movement ... valuable insight into how complex periodic patterns in biological ...
... 2009 Alexopoulos Prize will be given to Dr. Brian Shaw, ... July 29 in Snowbird, Utah. The honor based ... also known as the Outstanding Early-Career Mycologist Award of the ... papers and four review papers in 12 years. Both the ...
Cached Biology News:Possible drug target found for one of the most aggressive breast cancers 2Spontaneous assembly 2Spontaneous assembly 3Spontaneous assembly 4
(Date:5/23/2013)... 23, 2013  BioScrip, Inc. (NASDAQ: BIOS ... the Jefferies 2013 Global Healthcare Conference to be held ... Richard Smith , President ... , Chief Financial Officer, will present on Monday, ... About BioScrip BioScrip, Inc. provides ...
(Date:5/23/2013)... Can economic incentives such as gift cards, ... the public to increase their donations of blood? , ... Business School Assistant Professor Mario Macis says the ... body of recent research that supports their argument, the ... of Science that the World Health Organization and national ...
(Date:5/23/2013)... May 23, 2013 Graphite Metallizing ... self-lubricating bushings mounted in stainless steel pillow blocks. ... of GRAPHALLOY with the application and installation versatility ... Pillow Blocks work exceptionally well when submerged ... hostile liquids such as acids, alkalies, hydrocarbons, black ...
(Date:5/23/2013)... Patheon Inc ., a leading provider of contract ... will host a complimentary webinar on “Cleaning Validation: Science, ... 4, 2013 at 11 a.m. Eastern Standard Time. ... regulations for cleaning validation. Many companies have incorporated ... evaluation of risk. Some companies have chosen to ...
Breaking Biology Technology:Offering Economic Incentives to Attract Blood Donations Should Be Encouraged, Research Team writes in Science 2Offering Economic Incentives to Attract Blood Donations Should Be Encouraged, Research Team writes in Science 3Graphite Metallizing Now Offers GRAPHALLOY® Stainless Steel Pillow Blocks for Success in Submersible Applications 2Graphite Metallizing Now Offers GRAPHALLOY® Stainless Steel Pillow Blocks for Success in Submersible Applications 3Patheon to Present on “Cleaning Validation: Science, Risk and Novel Approaches to Testing” 2
... MichBio announced that,Johnson & Johnson Vice Chairman, Christine A. ... and Conference November 18-19 in Novi,Michigan. MichBio is the ... is the state,s premier life science event attracting,more than ... is one of the most respected professionals in the ...
... easy tips on adding ancestry tracing to their family events and ... of family celebrations everywhere. , ... Washington, DC (PRWEB) ... will have gathered in celebration of their family bonds. Funny ...
... Iceland, June 25 /PRNewswire-FirstCall/ -. deCODE genetics,(Nasdaq: DCGN ... presentations,at the company,s annual R&D event to be held ... on Monday, June 30, beginning at,1pm Eastern Time/5pm GMT/6pm ... The webcast is expected to last approximately three and ...
Cached Biology Technology:Christine Poon Will Keynote MichBio Expo 2Christine Poon Will Keynote MichBio Expo 3Families Embrace Science/Technology-based Ancestry Tracing Marking Milestone in Black Family Reunion Celebrations Across the Nation 2Families Embrace Science/Technology-based Ancestry Tracing Marking Milestone in Black Family Reunion Celebrations Across the Nation 3deCODE genetics to Webcast Presentations at Annual R&D Event 2deCODE genetics to Webcast Presentations at Annual R&D Event 3
Monoclonal antibodies conjugated with rhodamine...
... lightweight, the Moticam 2300 camera (MC2300) attaches ... eyetube, or trinocular port. Included in the ... Images 2.0ML software offers quick and accurate ... maximize resolution for examination or documentation purposes. ...
5X StabilCoat Immunoassay Stabilizer is a 5X concentrate solution of StabilCoat Immunoassay Stabilizer. The shelf-life of 5X StabilCoat Immunoassay Stabilizer is 2 years when stored at 4C. Product ...
... BSA-Free Stabilizer is a bovine protein-free ... It is an aqueous solution that ... MOPS buffer (3-(N-Morpholino) propanesulfonic acid), pH ... combination of 0.02% methylisothiazolone and 0.02% ...
Biology Products: