Navigation Links
NIA uses Genomatix in stem cell research, suggests novel transcription factors for stemness

Genomatix Software with businesses in Munich, Germany and Ann Arbor, Michigan released today that the group of Kenneth R. Boheler at the National Institute on Aging, National Institutes of Health, Baltimore, Md published some remarkable work on embryonic stem (ES) cells.

In their work they first identified and validated ES cell predominant transcripts by SAGE and qRT-PCR methods. Then they employed extensive DNA promoter analysis based on the integrated Genomatix system in order to identify conserved cis-elements and putative trans-regulators. Framework analysis for promoter organization, as introduced by Genomatix, increased likeliness for functional significance of the candidate transcription factors. Predictions were experimentally verified by Chromosomal Immunoprecipitation assays.

The study led to the novel identification of two transcription factors, B-Myb and Maz which are implicated either in the maintenance of the undifferentiated stem cell state or in early steps of differentiation.


Contact: Klaus May
Genomatix Software GmbH

Page: 1

Related biology news :

1. Computer-based tool aids research, helps thwart questionable publication practices
2. Widespread support for nonembryonic stem cell research, VCU Life Sciences Survey shows
3. New research suggests biofuel blending is often inaccurate
4. Study suggests genetic connection between short stature and arthritis
5. Deep-sea species loss could lead to oceans collapse, study suggests
6. BMI criteria for obesity surgery should be lowered, UT Southwestern researcher suggests
7. Study suggests link between obesity, poor bone health
8. Yale discovery suggests protein may play a role in severe asthma
9. Wasp genetics study suggests altruism evolved from maternal behavior
10. Misconceptions about Alzheimers varies among races, survey suggests
11. Feeling hot, hot, hot: New study suggests ways to control fever-induced seizures
Post Your Comments:
(Date:8/23/2017)... -- The general public,s help is being enlisted in what,s thought to be ... on the human body –and are believed to affect health.  ... The Microbiome Immunity Project is the largest study ... gut. The project's goal is to help advance scientific knowledge of the ... ...
(Date:6/30/2017)... , June 30, 2017 Today, ... developer and supplier of face and eye tracking ... Featured Product provider program. "Artificial ... innovative way to monitor a driver,s attentiveness levels ... from being able to detect fatigue and prevent ...
(Date:5/23/2017)... , May 23, 2017  Hunova, the first robotic gym for the ... been officially launched in Genoa, Italy . The first ... and the USA . The technology was developed ... market by the IIT spin-off Movendo Technology thanks to a 10 million ... News Release, please click: ...
Breaking Biology News(10 mins):
(Date:10/9/2017)... 2017  BioTech Holdings announced today identification and ... ProCell stem cell therapy prevents limb loss in ... demonstrated that treatment with ProCell resulted in more ... compared to standard bone marrow stem cell administration.  ... reduction of therapeutic effect.  ...
(Date:10/9/2017)... ... October 09, 2017 , ... The Giving Tree Wellness Center ... the needs of consumers who are incorporating medical marijuana into their wellness and ... , As operators of two successful Valley dispensaries, The Giving Tree’s two founders, ...
(Date:10/7/2017)... (PRWEB) , ... October 06, ... ... leader in Hi-C-based genomic technologies, launched its ProxiMeta™ Hi-C metagenome deconvolution product, ... Hi-C kit and accompanying cloud-based bioinformatics software to perform Hi-C metagenome deconvolution ...
(Date:10/6/2017)... D.C. (PRWEB) , ... October 06, 2017 , ... ... will host a lunch discussion and webinar on INSIGhT, the first-ever adaptive clinical ... Principal Investigator, Dana-Farber Cancer Institute. The event is free and open to the ...
Breaking Biology Technology: