Navigation Links
NHLBI awards $11 million for molecular roadmap to chronic lung diseases
Date:10/7/2009

Researchers at National Jewish Health and four other research centers have been awarded an $11 million, two-year grant from the National Heart Lung and Blood Institute as part of the NIH Recovery Act that will allow a team of national scientists to delve deeply into the biology of two fatal lung diseases for which there are few therapeutic options. The multi-center Lung Genomics Research Consortium will use advanced genetic and molecular tools to characterize and better understand chronic obstructive pulmonary disease and pulmonary fibrosis, then share its discoveries with researchers around the world in a web-accessible data warehouse.

"Our aim is create a genetic and molecular treasure trove for the research community to redefine these lung diseases precisely and unequivocally," said David Schwartz, MD, one of the lead researchers on the project and Director of The Center for Genes, Environment and Health at National Jewish Health. "The genetic, epigenetic, transcriptional, and phenotypic data we generate will provide an unprecedented window into the origins, dynamic biological features and unique presentations of these diseases. It will allow researchers to make fundamental discoveries that help identify individuals at risk for these diseases, diagnose them earlier, and develop more effective, personalized treatments."

Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in the United States. The incidence of pulmonary fibrosis has doubled over the past decade, and now kills about 40,000 Americans each year. There are few effective treatments for either disease, and both diseases are fatal.

Researchers will study tissue samples from the NHLBI Lung Tissue Research Consortium biorepository then combine the data they generate with pathobiological, clinical and radiological data already gathered for these samples. The biorepository now contains almost 1,300 well characterized tissue samples and collects about 250 additional samples per year from patients with COPD, pulmonary fibrosis and other chronic lung diseases.

This project will be led by a team of principal investigators, including David Schwartz, MD, at National Jewish Health, Mark Geraci, MD, at the University of Colorado Denver's School of Medicine; Naftali Kaminski, MD, and Frank Sciurba, MD, at the University of Pittsburgh School of Medicine; John Quackenbush, PhD, at the Dana-Farber Cancer Institute; and Avrum Spira, MD, at Boston University School of Medicine.


'/>"/>

Contact: William Allstetter
allstetterw@njc.org
303-398-1002
National Jewish Medical and Research Center
Source:Eurekalert

Related biology news :

1. NHLBI issues first US von Willebrand Disease clinical practice guidelines
2. NOAA awards funds to improve toxic algal bloom predictions in the Western Gulf of Mexico
3. International Rett Syndrome Foundation awards $2M for cutting-edge Rett syndrome research
4. Academies announce winners of 2009 Communication Awards
5. Siebel Foundation awards top UC San Diego bioengineering graduate students
6. WPI receives $1.3 million in federal awards for ongoing research in the life sciences
7. NIH announces 115 awards to encourage high-risk research and innovation
8. Duke biomedical scientists win 2 highly prized NIH Directors Awards
9. UNC scientists garner new NIH awards for high risk, transformative research
10. 2009 Lasker Awards recognize promise of stem cells -- global market could top $700 million
11. Australian filmmakers are stars of science film awards
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/16/2016)...   IdentyTechSolutions America LLC , a leading ... and a cutting-edge manufacturer of software and hardware ... seamless, integrated solutions that comprise IDT biometric readers ... provide IdentyTech,s customers with combined physical identification and ... and theft. "We are proud to ...
(Date:12/15/2016)... 2016   WaferGen Bio-systems, Inc. (NASDAQ: ... announced today that on December 13, 2016, it received ... Nasdaq Stock Market LLC which acknowledged that, as of ... common stock had been at $1.00 or greater for ... with Listing Rule 5550(a)(2) of the Nasdaq Stock Market. ...
(Date:12/15/2016)... "Increase in mobile transactions is driving the ... market is expected to grow from USD 4.03 billion ... a CAGR of 29.3% between 2016 and 2022. The ... demand for smart devices, government initiatives, and increasing penetration ... is expected to grow at a high rate during ...
Breaking Biology News(10 mins):
(Date:1/12/2017)... (PRWEB) , ... January 12, ... ... disposable devices with short response times capable of performing routine electrochemical biosensing ... disposable screen-printed electrodes provide fast, sensitive detection and quantification of various analytes ...
(Date:1/12/2017)... 2017   Protein Sciences Corporation , a ... Flublok Influenza Vaccine ®, announced today that its ... safety results and induced strong neutralizing antibodies against ... is expected to advance into human clinical trials ... Institute of Technology in Immunobiologicals of the Oswaldo ...
(Date:1/11/2017)... AURORA, Colo. (PRWEB) , ... January 11, 2017 ... ... in the journal Clinical Cancer Research show early promise of the investigational anti-cancer ... progressed despite a median 5 previous treatment regimens. Twenty-seven percent of these heavily ...
(Date:1/11/2017)... 11, 2017  Brian Mehling, M.D., world-renowned stem cell ... Horizon International (BHI), will be attending the 47th Annual ... from January 17-20, 2017. This will be Dr. ... The theme of this year,s forum is Responsive and ... will address strategies for fostering greater social inclusion and ...
Breaking Biology Technology: