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NEWMEDS announces new drug database
Date:11/9/2010

In a remarkable and unprecedented collaboration NEWMEDS (Novel Methods leading to NeW MEdications in Depression and Schizophrenia) have pooled resources to bring together data of 23,401 anonymized patients from 67 trials on 11 compounds in over 25 countries to form the single largest database of clinical trial data ever amassed in psychiatric research.

It is widely recognized that despite tremendous growth in biomedical knowledge, the deciphering of human genome and almost daily round of discoveries the rate of development of new drugs has been slow. This is especially true in psychiatric disorders. One barrier to development has been the competitive relationship between rival companies and the other has been the limited exchange of science across the industry-academic divide.

In September 2009, the Innovative Medicines Initiative (a Joint Undertaking between EU and EFPIA) launched a unique collaboration especially to address this issue in the area of psychiatric drug development: NEWMEDS (Novel Methods leading to NeW MEdications in Depression and Schizophrenia). NEWMEDS, led collaboratively by Dr. Tine Bryan Stensbl (H. Lundbeck A/S) and Professor Shitij Kapur (Institute of Psychiatry, King's College London) brings together seven academic research institutions, nine major pharmaceutical companies and three small and medium-sized enterprises into one consortium to overcome three major bottlenecks in developing models and methods in drug discovery as they relate to schizophrenia and depression. These bottlenecks are lack of accurate animal models to guide drug discovery, lack of tools and tests in healthy volunteers that can provide early indication of efficacy; and reliance on a clinical trial methodology that has remained rather unchanged for 50 years.

To identify how modern clinical trials might be improved the companies needed to collaborate to share their data and devise new ways of predicting which treatment is likely to work
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Contact: Louise Pratt
louise.pratt@kcl.ac.uk
44-207-848-5378
King's College London
Source:Eurekalert

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