Navigation Links
NCI partners with Jackson Laboratory, UC Davis to speed cancer clinical trials
Date:6/10/2011

ASCO Annual Meeting in Chicago on June 6, and will be presented at the World Conference on Lung Cancer in Amsterdam on July 6.

Data to be presented at the conferences will provide insights into the transition from empiric to rationally selected and personalized therapy utilizing the platform. The iGXT Platform is currently being employed in studies of Non-Small Cell Lung Cancer (NSCLC) involving Epidermal Growth Factor Receptor (EGFR)-directed therapies, mutation-specific GEMM and PDX models, and in conjunction with genome-wide assessment of altered gene expression and other molecular changes, pre-and post-therapy.

Future plans are for the platform to expand into brain cancers, ovarian cancer, prostate cancer and melanoma.

Specific studies are currently being conducted in collaboration with pharmaceutical companies and others in the biomedical research community. Organizations are encouraged to inquire about access to the platform for specific studies, and for models and materials that are available through the Center for Advanced Preclinical Research and Jackson Laboratory programs.

"There is an urgent need for more predictive models of human cancer for drug discovery," said Chuck Hewett, Ph.D., Executive Vice President and COO of The Jackson Laboratory. "Unfortunately, nine out of 10 cancer drugs entering preclinical testing fail. This comes at great cost to the pharmaceutical industry and to patients. The integrated approach we have with CAPR and UC Davis targets these issues directly."

David Hoekzema, Vice President for Business Development at SAIC-Frederick, said, "Knowledge of the genetic basis of human cancers can be combined with advanced genetic engineering techniques to produce lab animals that mimic the diseases in humans more accurately than traditional experimental mouse models. By integrating CAPR's expertise in this area with the unique capabilities of JAX, and into the clinical environment of UC Davis
'/>"/>

Contact: Joyce Peterson
joyce.peterson@jax.org
207-288-6058
Jackson Laboratory
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. GUMC and Oak Ridge National Labs announce unique research partnership
2. NIH funds 16 Science Education Partnership Awards
3. Elsevier partners with the Royal Netherlands Society for Agricultural Sciences
4. Montana State partnership receives $66.9M for carbon sequestration
5. New publishing partnership for Energy for Sustainable Development
6. Springer partners with Botanical Society of Korea
7. International public-private partnership offers new paradigm for medicinal chemistry
8. National Lung Cancer Partnership and LUNGevity Foundation announce 2009 grant recipients
9. NTU seals global partnerships on environmental sciences R&D
10. Oxford Journals and the International Society for Computational Biology announce new partnership
11. UC and partners awarded $23 million to transform discoveries into real-world health solutions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... creating a new professorship in tissue engineering to ... Molecular Engineering and the Marine Biological Laboratory, supported ... and Eugene Bell Foundation., The Eugene Bell Professorship ... for Molecular Engineering. That endowed chair holder also ... Eugene Bell Center for Regenerative Biology and Tissue ...
(Date:7/11/2014)... Shenzhen, July 10, 2014---A team of researchers from The ... have identified a gene of wild soybean linked to ... to grow in saline soil. This study published online ... to unveil novel genomic information for crop improvement. , ... to domestication and human selection, cultivated soybeans have less ...
(Date:7/11/2014)... University, Sweden, have explored two different ways that ... leading to the formation of oxygen molecules in ... the scientific journal Nature Communications . , ... synthetic catalysts for water oxidation, which are key ... direct storage of solar energy in fuels like ...
Breaking Biology News(10 mins):New professorship in tissue engineering links molecular engineering, marine biology 2BGI reports a novel gene for salt tolerance found in wild soybean 2Molecular snapshots of oxygen formation in photosynthesis 2
... of Warwick are examining a way of using bacteria ... that are difficult to create synthetically on a lab ... called prodiginines. , This group of antibiotics has ... to target and kill cancer cells. A synthetic prodiginine ...
... newly created by the University of California, Berkeley, and Lawrence ... the body's cells that can be flipped on and off ... Optical switches like these could trigger a chemical reaction, initiate ... cell - all at the flash of a light. ...
... engineers have developed a computer tool they say could ... women to use to prevent infection by the virus ... is a pressing challenge because women now account for ... said. , By applying fundamentals of physics and chemistry, ...
Cached Biology News:Light-sensitive photoswitches could restore sight to those with macular degeneration 2Light-sensitive photoswitches could restore sight to those with macular degeneration 3Study defines effective microbicide design for HIV/AIDS prevention 2Study defines effective microbicide design for HIV/AIDS prevention 3
(Date:7/11/2014)... , July 11, 2014 /CNW/ - Sunovion Pharmaceuticals Canada ... TM (eslicarbazepine acetate) for use as a once-daily ... patients with epilepsy who are not satisfactorily controlled with ... use in patients under 18 years of age. ... neurological disorders and according to Epilepsy Canada, it affects ...
(Date:7/10/2014)... Ouagadougou, Burkina Faso (PRWEB) July 10, 2014 ... Burkina Faso, today have access to an additional ... to increase access to contraception at all levels ... combining a lower-dose formulation of a widely used ... injection system. , Burkina Faso is the first ...
(Date:7/10/2014)... Understanding the need for better quality and ... gap that currently exists in this area, ChanTest has ... of validated ion channel and GPCR cell lines. ... ion channels control many critical physiological functions throughout the ... potential to treat a variety of human diseases. ...
(Date:7/10/2014)... Robert Harman, DVM, Founder and CEO of Vet-Stem, Inc., the ... relaunch of his highly informative blog, now named Stem Cells ... are Stem Cells ?” Dr. Harman’s purpose for blogging ... basics of stem cell therapy so that pet owners can ... when considering regenerative medicine. , A veterinarian by trade, Dr. ...
Breaking Biology Technology:Sunovion Pharmaceuticals Canada Inc. Announces Health Canada Approval of APTIOM(TM) (eslicarbazepine acetate) as a Once-Daily Adjunctive Treatment for Partial-Onset Seizures in Patients with Epilepsy 2Sunovion Pharmaceuticals Canada Inc. Announces Health Canada Approval of APTIOM(TM) (eslicarbazepine acetate) as a Once-Daily Adjunctive Treatment for Partial-Onset Seizures in Patients with Epilepsy 3Sunovion Pharmaceuticals Canada Inc. Announces Health Canada Approval of APTIOM(TM) (eslicarbazepine acetate) as a Once-Daily Adjunctive Treatment for Partial-Onset Seizures in Patients with Epilepsy 4Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 2Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 3Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 4Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 5Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 6Leader in Ion Channel Research Announces Newly Validated and Re-Engineered Cells 2Leader in Ion Channel Research Announces Newly Validated and Re-Engineered Cells 3Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 2Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 3
... Feb. 13 Pharmacyclics, Inc.,(Nasdaq: PCYC ) today ... 2008. The net loss for the second quarter of fiscal ... net loss of $5.9 million,or $0.23 per share, in the ... Total operating expenses were $4.9 million in the second quarter ...
... China, Feb. 13 /PRNewswire-Asia-FirstCall/ -- Shengtai,Pharmaceutical, Inc. (OTC ... manufacturer and distributor of high-quality, pharmaceutical grade,glucose products ... second,quarter of fiscal 2009 ended December 31, 2008. ... glucose products increased during the second quarter,compared with ...
... Creation Best Practice Findings to be released at SiriusDecisions B-to-B ... ... February 13, 2009 -- SiriusDecisions, the world,s leading source for ... announced that top executives from Hewlett-Packard Company, IBM Corporation and ...
Cached Biology Technology:Pharmacyclics Reports Second Quarter Fiscal 2009 Financial Results 2Pharmacyclics Reports Second Quarter Fiscal 2009 Financial Results 3Pharmacyclics Reports Second Quarter Fiscal 2009 Financial Results 4Pharmacyclics Reports Second Quarter Fiscal 2009 Financial Results 5Pharmacyclics Reports Second Quarter Fiscal 2009 Financial Results 6Pharmacyclics Reports Second Quarter Fiscal 2009 Financial Results 7Shengtai Pharmaceutical, Inc. Reports Second Quarter Fiscal 2009 Financial Results 2Shengtai Pharmaceutical, Inc. Reports Second Quarter Fiscal 2009 Financial Results 3Shengtai Pharmaceutical, Inc. Reports Second Quarter Fiscal 2009 Financial Results 4Shengtai Pharmaceutical, Inc. Reports Second Quarter Fiscal 2009 Financial Results 5Shengtai Pharmaceutical, Inc. Reports Second Quarter Fiscal 2009 Financial Results 6Shengtai Pharmaceutical, Inc. Reports Second Quarter Fiscal 2009 Financial Results 7Shengtai Pharmaceutical, Inc. Reports Second Quarter Fiscal 2009 Financial Results 8Shengtai Pharmaceutical, Inc. Reports Second Quarter Fiscal 2009 Financial Results 9Shengtai Pharmaceutical, Inc. Reports Second Quarter Fiscal 2009 Financial Results 10Shengtai Pharmaceutical, Inc. Reports Second Quarter Fiscal 2009 Financial Results 11Senior Executives from HP, IBM and Omniture Headline "Leaders and Lessons Learned" Sales and Marketing Summit 2009 2Senior Executives from HP, IBM and Omniture Headline "Leaders and Lessons Learned" Sales and Marketing Summit 2009 3
Porcine Aortic Endothelial Cells (PAOEC) (>500,000 cells)...
Bovine Endometrium Epithelial Cells (BEnEpC) (>500,000 cells)...
PC based system for advanced chemifluorescent, chemiluminescent, fluorescent and colorimetric, microarray and microscope imaging and analysis....
Pendrin (H-195)...
Biology Products: