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NASA technology key component of new diagnostic aid from DynaDx
Date:10/20/2009

GREENBELT, Md. NASA technology will now be available to the medical community to help in the diagnosis and prediction of syndromes that affect the brain, such as stroke, dementia, and traumatic brain injury.

DynaDx Corporation of Mountain View, Calif. has released the Multimodal Pressure-Flow (MMPF) technique for analysis of dynamic cerebral autoregulationthe ability of cerebral vessels to maintain a constant blood flow despite changes in arterial blood pressurethat incorporates the Hilbert-Huang Transform (HHT) technology licensed from NASA's Goddard Space Flight Center in Greenbelt, Md.

DynaDx obtained exclusive rights to HHT, an algorithm used to analyze nonlinear, nonstationary signals, from Goddard in the first ever sale of a government-owned patent license conducted through a public auction of intellectual property.

MMPF is a unique computational method for analyzing and evaluating autoregulatory dynamics, based on instantaneous phase analysis of nonlinear and nonstationary signals from blood pressure and cerebral blood flow velocity oscillations.

Medical professionals can use the data from MMPF to create a reliable index of cerebral autoregulation, and to help identify impairment of cerebral vasoreactivity, which is caused by medical conditions such as traumatic brain injury or stroke and is associated with other conditions such as hypertension and diabetes.

The Web-based MMPF data-analysis product has potential use for medical diagnosis and prediction in a wide range of clinical settings. One possible application is a portable device for use by medical personnel at sporting events to identify the extent of head trauma in athletes.

"We are very excited about MMPF and its potential to vastly improve existing methods used for diagnosis and prediction of syndromes that affect the brain," said Yanhui Liu, PhD and CEO of DynaDx. "HHT is essential for providing fast and reliable results, and we could not
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Contact: Darryl Mitchell
darryl.r.mitchell@nasa.gov
301-286-5169
NASA/Goddard Space Flight Center
Source:Eurekalert

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