Navigation Links
NASA technology key component of new diagnostic aid from DynaDx

GREENBELT, Md. NASA technology will now be available to the medical community to help in the diagnosis and prediction of syndromes that affect the brain, such as stroke, dementia, and traumatic brain injury.

DynaDx Corporation of Mountain View, Calif. has released the Multimodal Pressure-Flow (MMPF) technique for analysis of dynamic cerebral autoregulationthe ability of cerebral vessels to maintain a constant blood flow despite changes in arterial blood pressurethat incorporates the Hilbert-Huang Transform (HHT) technology licensed from NASA's Goddard Space Flight Center in Greenbelt, Md.

DynaDx obtained exclusive rights to HHT, an algorithm used to analyze nonlinear, nonstationary signals, from Goddard in the first ever sale of a government-owned patent license conducted through a public auction of intellectual property.

MMPF is a unique computational method for analyzing and evaluating autoregulatory dynamics, based on instantaneous phase analysis of nonlinear and nonstationary signals from blood pressure and cerebral blood flow velocity oscillations.

Medical professionals can use the data from MMPF to create a reliable index of cerebral autoregulation, and to help identify impairment of cerebral vasoreactivity, which is caused by medical conditions such as traumatic brain injury or stroke and is associated with other conditions such as hypertension and diabetes.

The Web-based MMPF data-analysis product has potential use for medical diagnosis and prediction in a wide range of clinical settings. One possible application is a portable device for use by medical personnel at sporting events to identify the extent of head trauma in athletes.

"We are very excited about MMPF and its potential to vastly improve existing methods used for diagnosis and prediction of syndromes that affect the brain," said Yanhui Liu, PhD and CEO of DynaDx. "HHT is essential for providing fast and reliable results, and we could not have developed MMPF without it."

A primary role of Goddard's Innovative Partnerships Program (IPP) Office is to help transfer NASA technology to the commercial marketplace and facilitate the creation of products that will ultimately benefit the agency and the public at large. HHT, which was developed by NASA, is being used to help improve the diagnosis and treatment of conditions of the brain, such as traumatic brain injury. The partnership with DynaDx is groundbreaking because it stemmed from a process that has successfully blazed a new trail to commercialization.

The exclusive license for HHT, composed of a portfolio of ten U.S. patents and one domestic patent application, was part of a lot auctioned by Ocean Tomo Federal Services, LLC on October 30, 2008. The auction was Ocean Tomo's largest to date, with over 500 in attendance.

"Government labs and businesses have been paying close attention to the auctioning of Goddard technologies through Ocean Tomo and the process that was used to license HHT to DynaDx," said Goddard Chief Patent Counsel Bryan Geurts. "When our lot sold at the auction, there was applause from the audience. Now that DynaDx has unveiled this new product, we have stronger indicators that the model works."

The primary benefit of the public auction through Ocean Tomo is that it makes the IP licensing process quicker and easier, saving time and resources for small companies like DynaDx. The process is well defined and clear from the beginning, allowing companies to make a quick decision about whether to obtain the license on a defined timeline.

"NASA and DynaDx stand to benefit from our unique partnership, but the long-term benefits will be much broader," said Darryl Mitchell, a technology transfer manager in Goddard's IPP Office, which facilitated the licensing arrangement. "The public auction process will encourage collaboration between labs that have developed similar technology to provide attractive lots for bidders. This will maximize the value of technology research in federal labs for taxpayers and the nation."


Contact: Darryl Mitchell
NASA/Goddard Space Flight Center

Related biology news :

1. Yale scientists use nanotechnology to fight E. coli
2. Voice Biometrics Gains Traction as Most Accurate and Convenient Technology to Secure Customer Privacy
3. M2SYS Partners with SecuGen Corporation to Support Market Leading Hamster Plus Fingerprint Reader with Auto-On Technology
4. Silicon Valley Technology Leaders LaserCard Corporation and Tesla Motors Sign LaserPass Secure Access Deal
5. Nanotechnology: Whats that?
6. UCs NIH grant brings technology from outer space to playgrounds
7. BIO-key(R) International to Showcase Deployed Biometric Security Applications at 2007 Biometric Technology Expo
8. Cogent Systems and Northrop Grumman Reach Agreement to Settle Automated Fingerprint Identification Technology Suit and Create Strategic Alliance
9. UCLA/VA partners with ASU to advance biosensor technology for urinary tract infections
10. Herr receives Heinz Award for Technology, the Economy and Employment
11. Singapore National Science and Technology Awards
Post Your Comments:
(Date:11/9/2015)... SAN JOSE, Calif. , Nov. 9, 2015 /PRNewswire/ ... of human interface solutions, today announced broader entry into ... of vehicle-specific solutions that match the pace of consumer ... drivers, and biometric sensors are ideal for the automotive ... the vehicle. Europe , ...
(Date:10/29/2015)... 29, 2015   MedNet Solutions , an innovative ... of clinical research, is pleased to announce that it ... (MHTA) as one of only three finalists for a ... Small and Growing" category. The Tekne Awards honor ... superior technology innovation and leadership. iMedNet™ ...
(Date:10/29/2015)... ANN ARBOR, Mich. , Oct. 29, 2015 ... with Eurofins Genomics for U.S. distribution of its ... DNA-seq kit and Rubicon,s new ThruPLEX Plasma-seq ... DNA to enable the preparation of NGS libraries ... in plasma for diagnostic and prognostic applications in ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... November 25, 2015 The ... is a professional and in-depth study on the ...      (Logo: ) , ... industry including definitions, classifications, applications and industry chain ... the international markets including development trends, competitive landscape ...
(Date:11/24/2015)... Nov. 24, 2015 Halozyme Therapeutics, Inc. (NASDAQ: HALO ... New York on Wednesday, December 2 at ... , president and CEO, will provide a corporate overview. ... at 1:00 p.m. ET/10:00 a.m. PT . ... will provide a corporate overview. --> th Annual ...
(Date:11/24/2015)... RALEIGH, N.C. , Nov. 24, 2015  Clintrax Global, Inc., ... Raleigh, North Carolina , today announced that the company has ... earnings represented a 391% quarter on quarter growth posted for Q3 ... Kingdom and Mexico , with the ... place in December 2015. --> United Kingdom ...
(Date:11/24/2015)... New York , November 24, 2015 ... to a recent market research report released by Transparency ... projected to expand at a CAGR of 17.5% during ... "Non-invasive Prenatal Testing Market - Global Industry Analysis, Size, ... estimates the global non-invasive prenatal testing market to reach ...
Breaking Biology Technology: