Navigation Links
NAS report offers new tools to assess health risks from chemicals
Date:10/10/2007

Determining how thousands of chemicals found in the environment may be interacting with the genes in your body to cause disease is becoming easier because of a new field of science called toxicogenomics. A new report issued today by the National Academies of Sciences (NAS) recognizes the importance of toxicogenomics in predicting effects on human health and recommends the integration of toxicogenomics into regulatory decision making. The NAS report was commissioned by the National Institute of Environmental Health Sciences (NIEHS) part of the National Institutes of Health (NIH) and a leader in the development of toxicogenomic technologies.

Toxicogenomic technologies provide tools to better understand the mechanisms through which environmental agents initiate and advance disease processes. They can also provide important information to help identify individuals that are more susceptible to disease risks posed by certain environmental agents than the general population.

Using toxicogenomic technologies will open the door for public health decision makers who need to decide in a timely and accurate manner what chemicals are safe and which ones are not, says Christopher Portier, Ph.D., Associate Director, NIEHS and Director, Office of Risk Assessment Research.

The report from the NAS National Research Council (NRC) entitled Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment states that the technological hurdles that could have limited the reproducibility of data from toxicogenomic technologies have been resolved and recommends ways for the field to move forward.

NIH and others have invested in the development of these tools and have already tackled many of the tough technical questions. We are now ready to move to the next phase of technology development, refined standardization and validation, so these tools can be even more useful to regulatory agencies, says Portier.

The NIEHS and NTP have been steadily increasing the use of toxicogenomic and other technologies derived from the molecular biology revolution, said Samuel H. Wilson, M.D., NIEHS Acting Director. The research and initiatives supported through the National Center for Toxicogenomics and the Toxicogenomics Research Consortium, for example, were at the forefront of these technologies and were leaders in the development of many of the standards for quality and reproducibility that are used today.

The report, which was prepared by a panel of 16 scientists assembled by the NRC, provides a broad overview of the potential benefits arising from toxicogenomic technologies, describes challenges regarding use of new technologies, and provides 14 recommendations to achieve the potential benefits of these technologies.


'/>"/>

Contact: Robin Mackar
rmackar@niehs.nih.gov
919-541-0073
NIH/National Institute of Environmental Health Sciences
Source:Eurekalert

Related biology news :

1. Octopuses occasionally stroll around on two arms, UC Berkeley biologists report
2. Surprising findings reported about iron overload
3. Researchers report new pro-inflammatory role for anti-inflammatory enzyme
4. Biochemists report discovery of structure of major piece of telomerase; implications for cancer
5. Report that delayed motherhood decreases life expectancy of mouse offspring
6. AIDS Public Awareness Campaign Expands Following Report Of Rapidly Progressive HIV
7. Leprosy genome tells story of human migrations, French researchers report in Science
8. Novel live reporting system to track cells
9. Tulane researcher reports on origin of deadly fever outbreak
10. Report calls for improved monoclonal antibodies against solid tumors
11. Biased reporting found in cancer prognostic studies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/20/2017)... July 20, 2017 Delta (NYSE: DAL ) customers ... Delta aircraft at Reagan Washington National Airport (DCA). ... Delta launches biometrics to board aircraft ... Delta,s biometric boarding pass ... is now integrated into the boarding process to allow eligible Delta ...
(Date:6/23/2017)... and ITHACA, N.Y. , June ... Cornell University, a leader in dairy research, today announced ... designed to help reduce the chances that the global ... onset of this dairy project, Cornell University has become ... Sequencing the Food Supply Chain, a food safety initiative ...
(Date:5/23/2017)... 23, 2017  Hunova, the first robotic gym for the rehabilitation and ... launched in Genoa, Italy . The first 30 robots ... the USA . The technology was developed and patented ... the IIT spin-off Movendo Technology thanks to a 10 million euro investment ... please click: ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... United States multicenter, prospective clinical study that demonstrates the accuracy of the ... of identifying clinically significant acute bacterial and viral respiratory tract infections by ...
(Date:10/12/2017)... ... 2017 , ... AMRI, a global contract research, development and ... outcomes and quality of life, will now be offering its impurity solutions as ... regulatory requirements for all new drug products, including the finalization of ICH M7 ...
(Date:10/11/2017)... ... October 11, 2017 , ... At ... Purple announced Dr. Suneel I. Sheikh, the co-founder, CEO and chief research scientist ... has been selected for membership in ARCS Alumni Hall of Fame . ...
(Date:10/11/2017)... ... ... wash is a basic first aid supply for any work environment, but most personal eye ... first if a dangerous substance enters both eyes? It’s one less decision, and likely quicker ... eye piece. , “Whether its dirt and debris, or an acid or alkali, getting anything ...
Breaking Biology Technology: