oscience, chairman of the department of neuroscience and director of the Brain Institute at the Mount Sinai School of Medicine, in New York. The goal of Dr. Nestler's research is to better understand the molecular mechanisms of addiction and depression. He uses animal models to identify the ways in which drugs of abuse or stress change the brain to lead to addiction- or depression-like syndromes, information that helps him to develop improved treatments. From 2000 to 2008, he was Distinguished Professor and chair of the department of psychiatry at the University of Texas Southwestern Medical Center at Dallas and before that, for 18 years, professor of psychiatry, pharmacology and neurobiology at Yale University, where he also directed the Abraham Ribicoff Research Facilities and the Division of Molecular Psychiatry.
"Dr. Nestler has demonstrated a remarkable ability to focus on basic science that is directly relevant to severe forms of mental illness," commented Jack D. Barchas, M.D., Barklie McKee Henry Professor and Chair of Psychiatry, Weill-Cornell Medical College, who heads NARSAD's Goldman-Rakic Prize Selection Committee. "He has led research with direct relevance to fundamental processes in brain development, as well as our understanding of disorders such as depression and drug abuse."
NARSAD's 2008 Sidney R. Baer, Jr. Prize for Schizophrenia Research will be presented to Angus W. MacDonald, III, Ph.D., associate professor of psychology and director of the Translational Research in Cognitive and Affective Mechanisms Laboratory at the University of Minnesota. Dr. MacDonald's research focuses on understanding the genetic and neural causes of schizophrenia, and also encompasses ways in which patients can improve their brain and real-world functioning. In earlier research, he used functional neuroimaging to identify brain regions different in patients with schizophrenia and examined whether these same regions were affected in healthy people wit
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