Navigation Links
Mystery E. coli genes essential for survival of many species
Date:7/13/2009

Scientists have shown that E. coli one of the best known and extensively studied organisms in the world remains an enigma that may hold the key to human diseases, such as cancer.

The team, funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and based at the University of Dundee has examined the genome sequence of this workhorse of the laboratory and spotted three previously unknown genes that, it turns out, are essential for the survival of E. coli and one out of the three could also be implicated in cancer or developmental abnormalities in humans. These mystery genes are also found in numerous other creatures, suggesting a vital role for them across many species. The research will be published in the 1 August edition of the Journal of Bacteriology.

The effort over recent years to sequence genomes of various important species has uncovered many previously unknown genes. This has given scientists the opportunity to choose to study these genes now, rather than waiting for them to make themselves known serendipitously e.g. when they are implicated in disease. Professor Tracy Palmer and her colleagues have taken three genes identified through sequencing of the E. coli genome and studied them to discover their significance.

Professor Palmer said: "Scientists have been studying E. coli genes for many, many years and we thought we knew pretty much all there was to know we certainly didn't expect to find any more genes that are essential for survival!

"Finding out that these genes are essential in E. coli and also appear in the genomes of other species tells us that they are very important indeed. In the case of one of the genes it is also found in the human genome, which makes it especially interesting. The mystery remains as to what they actually do, but whatever it is, it must be really crucial.

"Because we now know that one of these genes is found
'/>"/>

Contact: Nancy Mendoza
press.office@bbsrc.ac.uk
44-179-341-3355
Biotechnology and Biological Sciences Research Council
Source:Eurekalert

Page: 1 2

Related biology news :

1. Mystery of bat with an extraordinary nose solved
2. Harvard scientists solve mystery about why HIV patients are more susceptible to TB infection
3. Scientists tackle the mystery of white-nose syndrome in bats
4. Scientists unravel the mystery of white-nose syndrome
5. Research team wins funds to unravel a DNA mystery
6. Genetic sleuth solves glaucoma mystery
7. Life secret exposed: Scientists unlock mystery of molecular machine
8. Biologists solve mystery of black wolves
9. Fishdunnit! Mystery solved
10. Fish guts explain marine carbon cycle mystery
11. Peering inside the skull of a mouse to solve meningitis mystery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2014)... (Sept. 22, 2014) As genetic sequencing technologies continue ... is a critical need to establish appropriate policies and ... experts have said. A special policy issue of the ... online today and edited by experts with the Center ... of Medicine gives policy makers the tools to jumpstart ...
(Date:9/22/2014)... Ill. Antarctic fishes that manufacture their own ... Ocean also suffer an unfortunate side effect, researchers ... their bodies resist melting even when temperatures warm. ... Proceedings of the National Academy of Sciences ... an undesirable consequence of the evolution of antifreeze ...
(Date:9/22/2014)... the fires captured in this image burn in Khabarovsk Krai, ... Dozens of red hotspots, accompanied by plumes of smoke mark ... blows to the east towards the Sea of Okhotsk. ... this area, swampy forest inhabit the central depression, and deciduous ... large wildfires are common in Russia in the summer, the ...
Breaking Biology News(10 mins):Experts provide much-needed policy analysis for clinical integration of next generation sequencing 2Experts provide much-needed policy analysis for clinical integration of next generation sequencing 3Study: Antifreeze proteins in Antarctic fishes prevent freezingand melting 2Study: Antifreeze proteins in Antarctic fishes prevent freezingand melting 3
... Medicine have developed a new animal model for studying hemophilia ... disorder. Hemophilia A, a hereditary defect that prevents blood from ... the factor VIII gene. Published online in the Journal ... better understanding of hemophilia A, according to first author and ...
... of the H5N1 ,bird flu, virus in South East Asia ... of wild birds could lead to global pandemic. Such fears ... Ecological Society,s Journal of Applied Ecology reveals why ... wildfowl is unlikely but also provides a new framework for ...
... Sept. 2, 2010 The American Society for Biochemistry ... week in response to the Aug. 23 ruling in ... that granted a preliminary injunction barring federal funding of ... said the decision, which came in response to a ...
Cached Biology News:Yale develops new animal model for hemophilia A 2Satellite data reveal why migrating birds have a small window to spread bird flu 2American Society for Biochemistry and Molecular Biology reacts to stem-cell ruling 2
(Date:9/22/2014)... SANTA CLARA, Calif. , Sept. 22, 2014 ... ), the leading source of health information, today released ... that provide novel insights regarding physician and patient perspectives ...  Dr. Eric Topol , a leading authority in ... as both Editor-in-Chief of Medscape and Chief Academic Officer ...
(Date:9/22/2014)... mouse model of pancreatic cancer identified distinct patterns of ... differences from the primary tumor that may contribute to ... reported in the Sept. 25 issue of Cell ... Cancer Center identified several different classes of pancreatic CTCs ... targets for improved treatment of the deadly tumor. ...
(Date:9/22/2014)... (PRWEB) September 22, 2014 Lawrence ... President John DeGioia on Friday renewed their institutional ... an additional five years to expand the collaborative ... nonproliferation and global climate, energy and environmental sciences. ... an MOU originally signed in December 2009 and ...
(Date:9/22/2014)... 22, 2014 Follow us ... natural biopolymers available in abundance in nature. These ... resources such as shells of crustaceans. The significant ... due to the high percentage of nitrogen present ... in various industries owing to its exclusive properties ...
Breaking Biology Technology:WebMD/Medscape Digital Technology Survey Reveals Unique Insights Into How Patients and Physicians Perceive the Role, Potential and Risks Associated with Digital Health Technologies 2WebMD/Medscape Digital Technology Survey Reveals Unique Insights Into How Patients and Physicians Perceive the Role, Potential and Risks Associated with Digital Health Technologies 3WebMD/Medscape Digital Technology Survey Reveals Unique Insights Into How Patients and Physicians Perceive the Role, Potential and Risks Associated with Digital Health Technologies 4Massachusetts General study reveals gene expression patterns in pancreatic CTCs 2Massachusetts General study reveals gene expression patterns in pancreatic CTCs 3Lawrence Livermore Renews Pact with Georgetown University to Expand Research and Education in Science and Policy 2Emergence of New Application Areas to Drive the Global Chitin and Chitosan Market, According to New Report by Global Industry Analysts, Inc. 2Emergence of New Application Areas to Drive the Global Chitin and Chitosan Market, According to New Report by Global Industry Analysts, Inc. 3
... FluForecast(R) warning in April 7th, 2008, a year before ... was able to state the likelihood of H1N1 outbreaks ... examines specific regions in virus genes which have been ... as published on the Web, stated that in H1N1 ...
... Cellectricon, a leading,provider of automated screening solutions ... BioFocus DPI, a contract research organization with,leading ... will utilize,Cellectricon,s Dynaflow(R)HT, a fully automated patch ... screening capacity, particularly,for fast ligand-gated ion channels. ...
... Microparticles AB, the Swedish,life science technology company, ... production based on supercritical fluid technology.,The Company,s ... drawbacks of traditional micronization and is well ... all the advantages of earlier supercritical,fluid technologies ...
Cached Biology Technology:Biotechnology Company, Replikins Ltd., Provided Advance Warning of Mexican H1N1 'Swine Flu' Virus Outbreak 2Biotechnology Company, Replikins Ltd., Provided Advance Warning of Mexican H1N1 'Swine Flu' Virus Outbreak 3Cellectricon and BioFocus DPI Advance High Throughput ion Channel Drug Discovery 2Xspray Expands to Meet Pharma's Interest in its Ground-Breaking Particle Production Technology 2Xspray Expands to Meet Pharma's Interest in its Ground-Breaking Particle Production Technology 3
BioGenex IHC Kits for Rodent Tissues are designed for immunohistochemistry on rodent and rabbit tissues that are closely related to the source of the primary antibody. This kit comes with rat seconda...
... is available in a ready-to-use format. ... for dewaxing paraffin-embedded tissue sections prior ... or other analytical methods. The conventional ... dipping the slides in a series ...
... The BioGenex Super ... System is a novel ... proprietary non-biotin polymeric technology. ... high signal to noise ...
... thermal cycler is a compact instrument for gene ... tubes, 12 x 0.5 ml tubes, or a ... a thumbwheel to adjust height and pressure to ... heat pumps provide excellent thermal performance, and the ...
Biology Products: