Navigation Links
Mutant prions help cells foil harmful protein misfolding
Date:3/20/2011

to prion infection in nature, they haven't been successful in reversing an established infection because sustained delivery into the body is too challenging. However, a small molecule drug mimic, if developed, could target infected tissues more effectively over a longer period to slow or perhaps even reverse disease progression.

In the paper the researchers conclude, "A system-based approach to prion intervention represents a potentially promising direction in which to explore future therapies."


'/>"/>

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Oncogene AEG-1 strongly predicts response to erlotinib treatment in EGFR-mutant lung cancer
2. Mechanism behind demethylation pinpointed in APC gene mutants
3. Mutant gene link to West Nile virus in horses
4. Small molecules might block mutant protein production in Huntingtons disease
5. 200,000 rice mutants available worldwide for scientific investigation
6. 200,000 rice mutants available worldwide for scientific investigation
7. Mutant host cell protein sequesters critical HIV-1 element
8. Scripps Research scientists show prions mutate and adapt to host environment
9. Scripps research study shows infectious prions can arise spontaneously in normal brain tissue
10. Scripps Florida scientists show lifeless prions capable of evolutionary change and adaptation
11. Enzyme can steer cells or possibly stop them in their tracks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... to acquire and creatively manipulate spoken language is unique ... past 6 million years of human evolution to make ... best candidate gene we now have," says Wolfgang Enard, ... his efforts to understand the molecular biological basis of ... The results of his latest study, undertaken in collaboration ...
(Date:9/18/2014)... happy-go-lucky characters, so you might expect that most would ... fact some dogs are distinctly more pessimistic than others, ... "This research is exciting because it measures positive and ... offers researchers and dog owners an insight into the ... Melissa Starling, from the Faculty of Veterinary Science. Her ...
(Date:9/18/2014)... that when people are too stressed they are often ... Brain Mind Institute (BMI) at EPFL have just highlighted ... chronic stress and the loss of social skills and ... a synaptic regulatory molecule in the brain. This was ... . , Carmen Sandi,s team went to look ...
Breaking Biology News(10 mins):Language evolution: Quicker on the uptake 2Language evolution: Quicker on the uptake 3Dogs can be pessimists too 2Dogs can be pessimists too 3How stress tears us apart 2
... For Immediate Release A group of researchers at ... Institute has published a paper that reviews new strategies ... whether people are predisposed to developing common conditions like ... age, the entire DNA sequences, or "genomes," of humans ...
... immune cell that directs other cells to fight infection ... in both health and disease. Researchers from the University ... stimulatory molecule and a protein found on the membrane ... multi-taskers of sorts. Th17 cells protect the body against ...
... ARLINGTON, Va. - To expand collaboration and initiatives, the ... be held Nov. 8-10, will explore a wide range ... explosive devices. Hosted by the Office of Naval ... Hyatt Regency in Crystal City, Va., and will feature ...
Cached Biology News:Scientists describe new approach for identifying genetic markers for common diseases 2Scientists describe new approach for identifying genetic markers for common diseases 3Penn study shows 2-sided immune cell could be harnessed to shrink tumors 2
(Date:9/18/2014)... -- MEI Pharma, Inc. (Nasdaq: MEIP ), an oncology ... cancer, announced today that Daniel P. Gold , Ph.D., ... NewsMakers in the Biotech Industry conference on Friday, September ... Broadway Hotel & Conference Center in New York ... accessed at www.meipharma.com . A replay will be available ...
(Date:9/18/2014)... 18 septembre 2014 Mapi, société créée ... 1974, a été depuis 40 ans l,un ... cliniques traditionnelles par des évaluations recentrées sur ... les impacts économiques des traitements. ... A cours d,une récente conférence téléphonique ...
(Date:9/18/2014)... SeqLL Inc., the owner of ... today the closing of a $1M Series-A funding ... Diagnostic Technologies, will increase the power of tSMS™ ... in March 2013 by Daniel Jones, a former ... BioSciences, SeqLL has continued to offer Helicos’ sequencing ...
(Date:9/18/2014)... sweeteners, promoted as aids to weight loss and diabetes ... and metabolic disease; and they do it in a ... the gut microbiota the substantial population of bacteria ... experiments in mice and humans, were published today in ... Elinav of the Weizmann Institute,s Immunology Department, who led ...
Breaking Biology Technology:MEI Pharma To Present At BioCentury's NewsMakers Conference 2MEI Pharma To Present At BioCentury's NewsMakers Conference 31974 - 2014 - Mapi fête ses 40 ans 2SeqLL Closes Series-A Funding Round for Expansion of Single Molecule Sequencing 2Gut bacteria, artificial sweeteners and glucose intolerance 2Gut bacteria, artificial sweeteners and glucose intolerance 3
... Agencourt offers primer walking sequencing of PCR products, plasmid inserts , ... in either raw or , purified form and ... Select from either single stranded coverage for confirmation sequencing , ... purposes. , ...
... , , ... sequence delineation on capillary electrophoresis, instrumentation. CleanSEQ has ... system with the, ABI 3700 and 3730xl sequencers. ... prone to evaporation and exposure to, air before ...
... , Agencourts RNAClean kit provides a ... purifying nucleic acid products generated in common enzymatic , ... formatted for microarray , gene expression analysis experiments ... automated formats. RNAClean eliminates the need for vacuum filtration or , ...
Cached Biology Technology:Primer Walking 2CleanSEQ on the ABI 3100 2CleanSEQ on the ABI 3100 3CleanSEQ on the ABI 3100 4RNAClean - RNA & cDNA in vitro Reaction Purification 2
... The MEGAscript RNAi Kit is ... large mass amounts of ready-to-use ... non-mammalian systems. The MEGAscript RNAi ... patented high-yield transcription technol-ogy and ...
UGT1A6 (D-20)...
... With its patented technology, the Lone Wolf ... any Normally Open proportional valve available on ... operation, provides repeatable high-speed performance, and ensures ... , Enhances system control and patient ...
Normal Hamster Serum...
Biology Products: