Navigation Links
Mutant gene link to West Nile virus in horses
Date:6/2/2010

The same mutated gene that makes humans more susceptible to the potentially fatal West Nile virus is also responsible for the virus affecting horses, according to scientists at the University of Adelaide, Australia.

A naturally occurring mutation of the OAS1 gene has now been confirmed as increasing the vulnerability of horses to the West Nile virus, thanks to a study led by Professor David Adelson (University of Adelaide) and conducted by PhD student Jonathan Rios (Texas A&M University).

The results of the study were published last month in the online peer-reviewed science journal PLoS One.

West Nile virus causes inflammation of the brain and spinal cord, resulting in paralysis and death in humans, horses, birds and other species.

"Horses have been seriously affected by the West Nile virus, especially in North America where vaccinations, treatments and the loss of horses have cost countless millions of dollars to horse owners, industry and the community," says Professor Adelson, who is Professor of Bioinformatics and Computational Genetics at the University of Adelaide's School of Molecular & Biomedical Science.

"The OAS gene cluster in horses most closely resembles that of humans. Because previous research had already identified mutations of OAS1 as playing a key role in the vulnerability of mice and humans to the West Nile virus, we felt it was worth investigating this potential link in horses.

"These genetic mechanisms seem to be playing a similar role in humans and horses in term
'/>"/>

Contact: Professor David Adelson, University of Adelaide
david.adelson@adelaide.edu.au
61-883-037-555
University of Adelaide
Source:Eurekalert

Page: 1 2

Related biology news :

1. Small molecules might block mutant protein production in Huntingtons disease
2. 200,000 rice mutants available worldwide for scientific investigation
3. 200,000 rice mutants available worldwide for scientific investigation
4. Mutant host cell protein sequesters critical HIV-1 element
5. No helicopter moms among Rutgers mutant mice
6. MIT researchers offer glimpse of rare mutant cells
7. Mutant gene identified as villain in hardening of the arteries
8. Mutant sperm guide clinicians to new diseases
9. Rutgers cell biologist pinpoints how RNA viruses copy themselves
10. Experimental treatment protects monkeys from lethal Ebola virus post-exposure
11. Immune evasion common in many viruses, bacteria and parasites is uncommon in M. tuberculosis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... , Dec. 22, 2014  NXT-ID, Inc. (NASDAQ: NXTD ... company focused on the growing mobile commerce market, announces it ... Robbins for the 2015 International CES debut of the ... will be at the NXT-ID booth January 6th and ...
(Date:12/19/2014)... Research and Markets ( http://www.researchandmarkets.com/research/8kmfcn/iphone_5s ) has ... Sensor - Apple/AuthenTec TMDR92 & Sapphire - Technology Report" ... http://photos.prnewswire.com/prnh/20130307/600769 Following the acquisition of ... feature with the iPhone 5S. It is currently the ...
(Date:12/19/2014)... Dec. 18, 2014   LaunchKey , the first decentralized ... and Internet of Things era, today announced the close ... round was led by Metamorphic Ventures with participation from ... VegasTechFund, and others.  LaunchKey has raised $4 million to ...
Breaking Biology News(10 mins):NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 3NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 4iPhone 5S Fingerprint Sensor - Apple/AuthenTec TMDR92 & Sapphire - Technology Report 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3
... diseases such as schizophrenia, major depression and cancer ... of dysfunctional genes. A novel computational biology method ... Abdi, PhD, http://www.njit.edu/news/2008/2008-367.php , associate professor in ... found a way to uncover the critical genes ...
... day Americans elect a new president, one of the nation,s ... Houston and outline the daunting global warming challenges awaiting the ... analysis at the National Center for Atmospheric Research (NCAR) in ... a colloquium Tuesday, Nov. 4. The event is free ...
... granted to the laboratory of William Roush, Ph.D., ... Research Institute. Other participants in the consortium are ... California, San Francisco (UCSF), and University of Washington. ... Translational Research Institute Medical Chemistry division and professor ...
Cached Biology News:NJIT professor finds engineering technique to identify disease-causing genes 2Climate change expert to discuss grim global warming predictions 2Scripps Florida scientists awarded $1.5M to fight major water and food parasites 2
(Date:1/22/2015)... | RBJ today announces the firm brokered a long-term lease ... leading biopharmaceutical company, at Two Ledgemont Center in ... , president, and Brian Cohen , senior vice president, ... at 95 Hayden Ave. Photo - http://photos.prnewswire.com/prnh/20150122/170765 ...
(Date:1/22/2015)... BOSTON , Jan. 22, 2015  Transwestern | RBJ today ... feet of office space for Shire a leading biopharmaceutical company, ... . Transwestern | RBJ,s Robert Richards , president, and ... the lease for the entire five-floor building at 95 Hayden ...
(Date:1/22/2015)... 2015 The laboratory information management systems ... a number of technological advancements due to factors such ... need to integrate healthcare systems, and increasing government support ... system integration. Key players in the market focus on ...
(Date:1/22/2015)... Rootstown, OH (PRWEB) January 22, 2015 Crystal ... announced today that it has received AOAC-PTM Certifications for the ... O111, O121, and O145; collectively referred to as STEC or ... at 1 colony forming unit (cfu) per 325 g of ...
Breaking Biology Technology:Transwestern | RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Transwestern?RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 3Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 4Crystal Diagnostics Awarded AOAC-PTM Accreditation for the Rapid Detection of “Big 6” E.coli Food Pathogens 2
... Cord Blood America, Inc . ( www.cordblood-america.com ) ... blood stem cell preservation company focused on bringing ... and internationally, today announced that revenues for 2011 increased 37 ... The Company announced a gross profit increase in 2011 of ...
... 2012   HemoShear, LLC , a biotechnology research company ... systems for discovery and assessment of new drug compounds, ... Heart Association,s Arteriosclerosis, Thrombosis and Vascular Biology (ATVB) conference ... at the Hilton Chicago, 720 South Michigan Avenue in ...
... A recent solicitation by the Defense Logistics Agency ... a deluge of orders for emergency radiation products supplier ... tablets provide protection against radioactive iodine in the event ... of nuclear weaponry in Asia and the Middle East ...
Cached Biology Technology:Cord Blood America Revenues Up 37 Percent to $5.67 Million in 2011 2HemoShear to Present at Arteriosclerosis, Thrombosis and Vascular Biology (ATVB) Conference 2Potassium Iodide Sales Surge on Heels of Large Government Order 2
... of mouse embryonic stem cells to dopaminergic ... midbrain, where they are mainly located in ... and the retrorubral field. These dopaminergic (DA) ... innervation ( e.g.projections to the caudate nucleus, ...
... screening and binding optimization and built on ... synthesis platform. Thousands of customer specified RNA ... Sciences can provide assistance with custom sequence ... of our comprehensive DNA/RNA Aptamer Microarray Service. ...
... C-terminal end of the mouse retinoic acid receptor beta (RAR*). The ... RAR*. The sequence of PEP-005 is (amino to carboxy terminus): C ... - S - V - E - N - S - G ... - L - Q (The N-terminal cysteine has been added to ...
... The ELx50 is a fast and versatile ... with our patented Dual-ActionTM 16-channel manifold. This ... the dispense and aspiration manifolds for overfill ... and 384-well formats. The problem of fitting ...
Biology Products: