Navigation Links
Mussels inspire innovative new adhesive for surgery
Date:1/9/2013

ally, neither product is effective when used on wet tissue, a requirement of internal organ surgery, nor are there any current commercially available tissue adhesives or sealants appropriate for both external and internal use.

The researchers tested the newly developed iCMBAs on rats, using the adhesive and finger clamping to close three wounds for two minutes. Three other wounds were closed using sutures. The researchers reported their findings in a recent issue of Biomaterials.

The iCMBAs provided 2.5 to 8.0 times stronger adhesion in wet tissue conditions compared to fibrin glue. They also stopped bleeding instantly, facilitated wound healing, closed wounds without the use of sutures and offered controllable degradation.

"If you want the material to stay there for one week, we can control the polymer to degrade in one week," said Yang. "If you want the material to stay in the wound for more than a month, we can control the synthesis to make the materials degrade in one month."

The iCMBAs are also non-toxic, and because they are fully synthetic, they are unlikely to cause allergic reactions. Side effects were limited to mild inflammation.

"If you put any synthetic materials into your body," said Yang, "the body will generate some inflammation."

The researchers are now working on improving the formula.

"We are still optimizing our formulation," said Yang. "We are still trying to make the adhesion strength even stronger" to expand its use for things like broken bones where strong adhesion is tremendously important.

The researchers are also looking at adding in components that could control infection.

"We can introduce another component with anti-microbial properties, so it can do two functions at once," said Yang.

The iCMBAs could eventually be used in a wide range of surgical disciplines from suture and staple replacement to tissue grafts to treat hernias, ulcers and burns.
'/>"/>

Contact: A'ndrea Elyse Messer
aem1@psu.edu
814-865-9481
Penn State
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Silicone foul release coatings show promise to manage invasive mussels at water facilities
2. Mussel goo inspires blood vessel glue
3. University of Tennessee engineering professor looks to whirligig beetle for bio-inspired robots
4. Inspired: Canada funds 68 bold, inventive ways to improve health, save lives in developing countries
5. Origami inspires research into materials that self-assemble when exposed to light
6. Rice receives $1 million INSPIRE award from National Science Foundation
7. Frog calls inspire a new algorithm for wireless networks
8. Human eye inspires clog-free ink jet printer invented by MU researcher
9. New book inspires children to protect dugongs
10. MVI and Inovio partner to develop malaria vaccines using innovative vaccine delivery tech
11. NIH awards Penn scientists $10 million over 5 years for innovative research on single cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... release is available in German . ... among the most expensive foods in the world. Because they ... them. But the distinctive smell of truffles is not only ... scientists under the direction of the Goethe University Frankfurt have ... by soil bacteria which are trapped inside truffle fruiting bodies. ...
(Date:9/30/2014)... involving mice and published in the October 2014 issue ... , suggests that just because you can do it, ... of Italian scientists have found that using marijuana in ... system. This damage may result in autoimmune diseases and ... disease and rheumatoid arthritis in adulthood. , "I hope ...
(Date:9/30/2014)... your doctor to know what goes wrong with your muscles ... to know what "normal" actually is. That,s where a new ... FASEB Journal comes in. In the ... set of molecules that can help scientists "see" which genes ... more, they found never-before-detected gene activity and that men have ...
Breaking Biology News(10 mins):On the trail of the truffle flavor 2Adolescent exposure to thc may cause immune systems to go up in smoke 2Scientists identify which genes are active in muscles of men and women 2
... a rock type found only in the world,s oldest oceans ... a foothold on the Earth. , A scientific team led ... Denmark, and including scientists from Newcastle University, UK, and universities ... managed to plot the rise and fall of oxygen levels ...
... since the Roman Empire employed a naturally occurring form ... aqueducts and other large edifices, researchers have analyzed the ... building materials such as steel, which has a well-documented ... enough, the three-dimensional crystalline structure of cement hydrate - ...
... Center will play host to one of the world,s premier ... and Chemotherapy (ICAAC). From September 12-15, nearly 8,000 scientists ... people. ICAAC has traditionally been an outlet for the ... Among the announcements expected next week: ...
Cached Biology News:Ancient oceans offer new insight into the origins of animal life 2Cement's basic molecular structure finally decoded 2Cement's basic molecular structure finally decoded 3
(Date:9/30/2014)... (PRWEB) September 30, 2014 Proove ... medicine, is excited to announce a new genetic test ... The Proove Pain Perception Test will provide physicians ... and why pain tolerance levels are stratified between individuals. ... identify whether a person has a genetic predisposition that ...
(Date:9/30/2014)... Fla. , Sept. 30, 2014 CORD:USE ... pleased to announce that it has entered into an ... Inc. (Tianhe) which has licensed a series of patented technologies ... cells for possible clinical applications.  Tianhe is performing Phase ... and Spain using Tianhe,s Stem ...
(Date:9/30/2014)... September 30, 2014 OriginOil Inc. (OTC/QB: ... chemical-free process to clean up large quantities of water, ... Riggs Eckelberry reported on the launch of the company's ... site provided by partner STW Resources . , ... barrels per day (bpd) and achieved a 99.8% reduction ...
(Date:9/30/2014)... DEL MAR, Calif. , Sept. 30, 2014 /PRNewswire/ ... devices for women,s health announces its receipt of a ... The FemmyCycle menstrual cup has also received FDA clearance ... Health Canada, and the CE in Europe. This patent is ... design. In conjunction with this issuance, the company is releasing ...
Breaking Biology Technology:Proove Biosciences is Now Offering the Proove Pain Perception Genetic Test to Help Physicians Assess Patient Pain Tolerance Levels 2Proove Biosciences is Now Offering the Proove Pain Perception Genetic Test to Help Physicians Assess Patient Pain Tolerance Levels 3CORD:USE is Pleased to Announce it has Partnered with Tianhe Stem Cell Biotechnologies, Developer of Cord Blood Stem Cell Therapy Showing Promising Results in Clinical Trials for the Treatment of Diabetes and Autoimmune Diseases 2CORD:USE is Pleased to Announce it has Partnered with Tianhe Stem Cell Biotechnologies, Developer of Cord Blood Stem Cell Therapy Showing Promising Results in Clinical Trials for the Treatment of Diabetes and Autoimmune Diseases 3CORD:USE is Pleased to Announce it has Partnered with Tianhe Stem Cell Biotechnologies, Developer of Cord Blood Stem Cell Therapy Showing Promising Results in Clinical Trials for the Treatment of Diabetes and Autoimmune Diseases 4OriginOil, Inc. Report to Shareholders: Blue Gold in West Texas 2The FemmyCycle 2
... Calif., Dec. 16, 2010 Zenobia Therapeutics, Inc. ... CNS diseases, announced today a research collaboration with ... protein expression and x-ray crystallography for the Parkinson,s ... continue to use its capabilities in fragment-based lead ...
... 15, 2010 /PRNewswire-Asia-FirstCall/ -- China-Biotics, Inc. ("China-Biotics" or "the ... manufacturer and distributor of probiotics products in China, today ... (the "Annual Meeting") will be held on Wednesday, March ... Meeting will be held at the Company,s executive offices ...
... ALEXANDRIA, Va., Dec. 14, 2010 The Association for ... Brief called, "CTE,s Role in Worker Retraining" that ... pivotal role in retraining adults and providing them the skills ... CTE worker retraining programs not only focus on local employment ...
Cached Biology Technology:Zenobia Therapeutics, Inc. Enters Into a Research Collaboration With Lundbeck for the Parkinson's Disease Target LRRK2 2China-Biotics, Inc. to Hold 2010 Annual Meeting of Stockholders on March 9, 2011 2China-Biotics, Inc. to Hold 2010 Annual Meeting of Stockholders on March 9, 2011 3ACTE Releases Issue Brief Outlining Critical Role CTE Plays in Worker Retraining 2
Mouse monoclonal antibody raised against a partial recombinant EOMES. NCBI Entrez Gene ID = EOMES...
...
Rabbit polyclonal to MCP2 ( Abpromise for all tested applications). entrezGeneID: 6355 SwissProtID: P49873...
Mouse monoclonal antibody raised against a partial recombinant AATK. NCBI Entrez Gene ID = AATK...
Biology Products: