Navigation Links
Mushroom compound suppresses prostate tumors
Date:5/23/2011

A mushroom used in Asia for its medicinal benefits has been found to be 100 per cent effective in suppressing prostate tumour development in mice during early trials, new Queensland University of Technology (QUT) research shows.

The compound, polysaccharopeptide (PSP), which is extracted from the 'turkey tail' mushroom, was found to target prostate cancer stem cells and suppress tumour formation in mice, an article written by senior research fellow Dr Patrick Ling in the international scientific journal PLoS ONE said.

Dr Ling, from the Australian Prostate Cancer Research Centre-Queensland and Institute for Biomedical Health & Innovation (IHBI) at QUT, said the results could be an important step towards fighting a disease that kills 3000 Australian men a year.

"The findings are quite significant," Dr Ling said.

"What we wanted to demonstrate was whether that compound could stop the development of prostate tumours in the first place.

"In the past, other inhibitors tested in research trials have been shown to be up to 70 per cent effective, but we're seeing 100 per cent of this tumour prevented from developing with PSP.

"Importantly, we did not see any side effects from the treatment."

Dr Ling said conventional therapies were only effective in targeting certain cancer cells, not cancer stem cells, which initiated cancer and caused the disease to progress.

During the research trial, which was done in collaboration with The University of Hong Kong and Provital Pty Ltd, transgenic mice that developed prostate tumours were fed PSP for 20 weeks.

Dr Ling said no tumours were found in any of the mice fed PSP, whereas mice not given the treatment developed prostate tumours. He said the research suggested that PSP treatment could completely inhibit prostate tumour formation.

"Our findings support that PSP may be a potent preventative agent against prostate cancer, possib
'/>"/>

Contact: Stephanie Harrington
stephanie.harrington@qut.edu.au
61-731-381-150
Queensland University of Technology
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Dried mushrooms slow climate warming in Northern forests
2. New species of phallus-shaped mushroom named after California Academy of Sciences scientist
3. Heavy metals accumulate more in some mushrooms than in others
4. Japanese gourmet mushroom found in Sweden
5. Duke team finds compounds that prevent nerve damage
6. Argonne scientists peer into heart of compound that may detect chemical, biological weapons
7. Discovery of natural compounds that could slow blood vessel growth
8. LSUHSC awarded patent for compound inhibiting cancer and other diseases
9. Resveratrol, red wine compound linked to health, also found in dark chocolate and cocoa
10. Design of a compound that stabilizes the main natural suppressor of tumors
11. New $11 million center to speed production of new compounds for drug discovery
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Mushroom compound suppresses prostate tumors
(Date:12/17/2014)... DUBLIN , Dec. 15, 2014 Research and Markets ... of the "Samsung Galaxy S5 - Home Button ... offering. http://photos.prnewswire.com/prnh/20130307/600769 ... the iPhone 5S, Samsung introduces for the first time ...
(Date:12/17/2014)... DENVER , Dec. 16, 2014  Automation is fundamentally ... evident than at international borders. Over the past decade, ... veteran travelers to self process through border control via ... increasing number of airports, seaports, and land borders across ...
(Date:12/11/2014)... , Dec. 10, 2014  Data Sciences International (DSI), ... released a new series of digital telemetry implants ... researchers. M series, part of the PhysioTel™ Digital ... best possible physiologic data when incorporating functional endpoints ...
Breaking Biology News(10 mins):Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2New telemetry implants expected to change how large animal toxicology studies are conducted 2
... , WASHINGTON, D.C., Dec. 15, 2011 Austen BioInnovation ... Drug Administration (FDA) have entered into a ground-breaking collaboration ... and effective use of biomaterials in medical devices. ... of Understanding that will allow the FDA to draw ...
... study has identified a gene mutation that researchers estimate dates ... disease mutation yet discovered. , Researchers with the Ohio State ... and Richard J. Solove Research Institute led the study and ... 13,600 years ago. Only a mutation seen in cystic fibrosis ...
... fetal exposure to carcinogens can vary substantially, a recent study ... depending on the stage of pregnancy when the fetus is ... in which toxic damage early in life can later manifest ... was done by scientists in the Linus Pauling Institute at ...
Cached Biology News:FDA, ABIA to collaborate on safety and performance of materials used in medical devices 2Scientists discover second-oldest gene mutation 2Cancer from fetal exposure to carcinogens depends on dose, timing 2
(Date:1/22/2015)... Jan. 22, 2015  Derma Sciences, Inc. (Nasdaq: ... on advanced wound care, announces that AMNIOEXCEL® and ... been added to the Premier, Inc. Regenerative Skin ... for the AMNIOEXCEL® and AMNIOMATRIX® product lines, which ...
(Date:12/24/2014)... AUSTIN, Texas , Dec. 24, 2014  Vermillion, ... focused on gynecologic disease, announced today that the ... investors including Oracle Investment Management, Jack W. ... directors. Total proceeds were $10.5 million, before offering ...
(Date:12/24/2014)... Earlier this year in a June 24 ... Adult Stem Cell Technology Center, LLC ( ASCTC ) focused ... of adult tissue stem cells. His title “Asymmetric Self-Renewal ... the Future,” embodied the essence of his message to congress ...
(Date:12/24/2014)... (PRWEB) December 23, 2014 The ... as its definition, classification, application and industry overview. ... and product cost structure. Production is separated by ... upstream raw materials, equipment, downstream client survey, marketing ...
Breaking Biology Technology:Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 3Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 5Vermillion Announces Closing of Equity Financing 2Vermillion Announces Closing of Equity Financing 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 4Worldwide Methyl Mercaptan Market 2015-2020 Forecasts on Development & Trends Now Available at ReportsnReports.com 2
... 17, 2011 Executives from NineSigma , Inc., the ... have written chapters on crucial elements of open innovation for ... Leading Experts. This bestselling book offers ... new solutions and capabilities outside of their organization and clearly ...
... and Ghent University have shown that a defective gene ... often-crippling inflammation of the joints that afflicts about 1% ... mechanism of the disease was largely unclear. In the ... demonstrate that a cell-specific defect in the expression of ...
... TARRYTOWN, N.Y., Aug. 16, 2011 Regeneron Pharmaceuticals, Inc. ... has received notification from the U.S. Food and Drug ... date to complete the priority review of the EYLEA ... age-related macular degeneration (wet AMD) to November 18, 2011, ...
Cached Biology Technology:From Leadership to Legal Issues, NineSigma Shares Best Practices in an Authoritative Guide to Open Innovation and CrowdSourcing 2Defect in A20 gene expression causes rheumatoid arthritis 2Regeneron Announces Review of Biologics License Application for EYLEA™ (aflibercept injection) Extended by Three Months by FDA 2Regeneron Announces Review of Biologics License Application for EYLEA™ (aflibercept injection) Extended by Three Months by FDA 3Regeneron Announces Review of Biologics License Application for EYLEA™ (aflibercept injection) Extended by Three Months by FDA 4
... DNA polymerase from Thermus aquaticus expressed in ... 1 tube of 250 units enzyme/tube and ... DNA), is the same enzyme as AmpliTaq ... a proprietary separation process to ensure that ...
... 5 units/µL ,• High specific activity and ... an 'A' overhang ,• Processes ... very high activity in primer extension and ... quality of the enzyme, each lot has ...
... AmpliTaq DNA Polymerase is the most thoroughly ... a testimony to its overall utility and ... it ideal for PCR applications. , ... results. ,, AmpliTaq DNA Polymerase is ...
Recombinant DNA polymerase from Thermus aquaticus expressed in E. coli; 5 units/uL; 25 tubes of 1, 000 units enzyme/tube w/ Buffer I...
Biology Products: