Navigation Links
Multiple sclerosis appears to originate in different part of brain than long believed
Date:9/10/2013

The search for the cause of multiple sclerosis, a debilitating disease that affects up to a half million people in the United States, has confounded researchers and medical professionals for generations. But Steven Schutzer, a physician and scientist at Rutgers New Jersey Medical School, has now found an important clue why progress has been slow it appears that most research on the origins of MS has focused on the wrong part of the brain.

Look more to the gray matter, the new findings published in the journal PLOS ONE suggest, and less to the white. That change of approach could give physicians effective tools to treat MS far earlier than ever before.

Until recently, most MS research has focused on the brain's white matter, which contains the nerve fibers. And for good reason: Symptoms of the disease, which include muscle weakness and vision loss, occur when there is deterioration of a fatty substance called myelin, which coats nerves contained in the white matter and acts as insulation for them. When myelin in the brain is degraded, apparently by the body's own immune system, and the nerve fiber is exposed, transmission of nerve impulses can be slowed or interrupted. So when patients' symptoms flare up, the white matter is where the action in the brain appears to be.

But Schutzer attacked the problem from a different direction. He is one of the first scientists to analyze patients' cerebrospinal fluid (CSF) by taking full advantage of a combination of technologies called proteomics and high-resolution mass spectrometry. "Proteins present in the clear liquid that bathes the central nervous system can be a window to physical changes that accompany neurological disease," says Schutzer, "and the latest mass spectrometry techniques allow us to see them as never before." In this study, he used that novel approach to compare the cerebrospinal fluid of newly diagnosed MS patients with that of longer term patients, as well as fluid ta
'/>"/>

Contact: Rob Forman
robert.forman@rutgers.edu
973-972-7276
Rutgers University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Clinical trial launches to see whether vitamin D helps treat multiple sclerosis
2. New data improve understanding of breast cancers multiple varieties
3. Researchers identify need to sample multiple tumor zones in breast cancer
4. Under the right conditions, peptide blocks HIV infection at multiple points along the way
5. Multiple sclerosis immune exchange between brain and blood is uncovered
6. Combination of two pharmaceuticals proves effective in the treatment of multiple sclerosis
7. Medbox, Inc. Featured in Multiple Media Stories in Massachusetts and California
8. Nursing gerbils unravel benefit of multiple mothers in collective mammals
9. Multiple sclerosis study reveals how killer T cells learn to recognize nerve fiber insulators
10. New research network for multiple sclerosis research
11. New research may aid treatment of multiple myeloma patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/16/2014)... they are anything but sustainable: environmental damage to ... becoming increasingly evident. Despite their disadvantages, however, monocultures ... as the sole possibility of achieving higher yields ... Schmid, an ecology professor at the University of ... and forestry. After all, a new study carried ...
(Date:10/16/2014)... Calif. (October 16, 2014) – Post-menopausal women experienced ... on hormone levels or genital bleeding, after 12 ... an investigational fermented soy germ-based nutritional supplement previously ... to a new peer-reviewed pilot study reported in ... (NAMS) annual scientific meeting. , "These data ...
(Date:10/15/2014)... N.Y. , Oct. 15, 2014 ... solutions for home and community-based care, today announced ... of implementing Sandata,s Santrax® Electronic Visit Verification™ Solution ... Services is a home health company founded in ... Texas . The study ...
Breaking Biology News(10 mins):Plant communities produce greater yield than monocultures 2Plant communities produce greater yield than monocultures 3S-equol supplements associated with improved measures of reproductive health in postmenopausal women 2Sandata Announces Case Study with Quality Care Services, Inc. 2
... CHAPEL HILL, N.C. A new study led by ... differences in brain development starting at age 6 months in ... who did not develop autism. "It,s a promising finding," ... and a postdoctoral fellow at UNC,s Carolina Institute for Developmental ...
... & Science University have discovered that brain cells ... critically important for the growth of brainstem neurons responsible ... the prevention and treatment of SIDS (Sudden Infant Death ... one month to one year. The new ...
... MADISON -- Nacre -- or mother of pearl, scientists and ... Produced by a multitude of mollusk species, nacre is ... musical instruments, furniture and decorative boxes. Fashioned into buttons, beads ... mother of pearl lends a lustrous iridescence to everyday objects. ...
Cached Biology News:Brain-imaging differences evident at 6 months in infants who develop autism 2OHSU discovery may someday lead to prevention and treatment of sudden infant death syndrome 2Mother of pearl tells a tale of ocean temperature, depth 2
(Date:10/19/2014)... The report "Unmanned Ground Vehicle Market by ... Type & by Geography - Forecasts & Analysis ... vehicle market into various sub segments with an ... report also identifies the factors driving this market, ... the adoption trends. , The unmanned ground vehicle ...
(Date:10/18/2014)... The Asian arthroscopic devices report defines and segments ... of revenue. The arthroscopic devices market in Asia is ... a CAGR of 6.5% from 2013 to 2018. , ... market, to get an idea of the in-depth analysis ... of arthroscopic devices market in the same region, and ...
(Date:10/18/2014)... According to a new market research report “Hydraulic ... Trends & Forecasts up till 2017”, hydraulic fracturing market ... value is expected to increase from $40 billion in ... during the same period. North America is expected to ... of hydraulic horse power supplied by the year 2011. ...
(Date:10/17/2014)... Germany , October 17, 2014 ... Translational research in cancer and other diseases will ... American Society of Human Genetics annual meeting   ... to Ingenuity ®  Knowledge Base greatly exceeds any ... Ingenuity ®  Variant Analysis™ adds fully integrated ...
Breaking Biology Technology:Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 2Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 3Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 4Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 5The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 2The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 3The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 4Hydraulic Fracturing Market Projected To Reach $64 Billion by 2017 - New Report by MarketsandMarkets 2Hydraulic Fracturing Market Projected To Reach $64 Billion by 2017 - New Report by MarketsandMarkets 3Hydraulic Fracturing Market Projected To Reach $64 Billion by 2017 - New Report by MarketsandMarkets 4QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 2QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 3QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 4QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 5QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 6
... Keryx Biopharmaceuticals,Inc. (Nasdaq: KERX ) today ... will present an overview of the Company,s cancer,pipeline ... Investment Conference,in San Francisco. Dr. Henderson,s presentation will ... PT. Dr. Henderson,s presentation will be webcast ...
... Mass., Sept. 17 Interleukin Genetics,(Amex: ILI ... Scientific,Officer, Kenneth Kornman, DDS, PhD, will present at ... Alexandria, VA. The conference will,focus on innovative methods ... Among a group of presenters that includes industry ...
... the U.S. Department of Energy,s Argonne National Laboratory physicist ... mechanisms, which makes it possible to switch a magnetic ... to more accurately write and store information. , Bode ... a special scanning tunneling microscope equipped with a magnetic ...
Cached Biology Technology:Keryx Biopharmaceuticals to Present at Bank of America Investment Conference 2Interleukin Genetics President and Chief Scientific Officer to Present at Immunotoxicology V Conference 2Interleukin Genetics President and Chief Scientific Officer to Present at Immunotoxicology V Conference 3Researchers improve ability to write and store information on electronic devices 2
Gloves are 9.25 long, latex, powder free, smooth and ambidextrous....
Request Info...
Prepared with distilled water. Yeast extract solution is autolyzed at 150 g/L....
Streptomycin sulfate an aminoglycoside used for bacterial selection binds to the small ribosomal subunit and interferes with protein biosynthesis.21H39N7O12)2x3H2SO4Formula weight:...
Biology Products: