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Multiple myeloma study uncovers genetic diversity within tumors
Date:1/13/2014

cells contains a BRAF mutation or another such mutation.

The problem of subclonal populations is not unique to multiple myeloma. Researchers are applying the same technique to explore other forms of cancer to look for populations of genetically diverse cells within a single tumor.

"In order to appropriately choose targeted therapy, we have to have those studies," said Lohr. "Matching the right drug to the right patient isn't as easy as finding a mutation and having a drug that targets it. We have to keep this additional parameter of heterogeneity in mind."


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Contact: Haley Bridger
hbridger@broadinstitute.org
617-714-7968
Broad Institute of MIT and Harvard
Source:Eurekalert

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