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Multi-institutional study identifies new form of inherited risk of cancer
Date:3/25/2008

l background, known as "endogamy." (This custom carries no social stigma; on the contrary, it is a source of pride in most cultures.) Since the other half of patients with IBD are of Catholic or Protestant heritage, the results of such an analysis pertain to all populations. The IBD regions reveal where researchers should look for novel genes, which contribute to the overall risk for this cancer.

Colorectal cancer results in more than 52,000 deaths each year in the United States, with more than 153,000 new cases diagnosed. About a third of cases run in families, and some of them are caused by a handful of well-studied genes. The genetic underpinnings of most of the more than a million cases of colorectal cancer worldwide are not known. This new approach of following IBD regions may clear up some of that mystery -- and ultimately, many others.


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Contact: Andrew Klein
ank2017@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

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