Navigation Links
Mouse study: When it comes to living longer, it's better to go hungry than go running
Date:5/13/2008

BETHESDA, Md. (May 14, 2008) A study investigating aging in mice has found that hormonal changes that occur when mice eat significantly less may help explain an already established phenomenon: a low calorie diet can extend the lifespan of rodents, a benefit that even regular exercise does not achieve.

We know that being lean rather than obese is protective from many diseases, but key rodent studies tell us that being lean from eating less, as opposed to exercising more, has greater benefit for living longer. This study was designed to understand better why that is, said Derek M. Huffman, the studys lead author.

The study applies only to rodents, which are different in some key ways from humans, cautions Huffman. However, at least two studies which examined people who engage in high-volume exercise versus people who restricted their calorie intake, had a similar outcome: caloric restriction has physiological benefits that exercise alone does not. Researchers expect that clues to the physiology of longevity in mice will eventually be applied to people, Huffman said.

The study, Effect of exercise and calorie restriction on biomarkers of aging in mice, appears in the May issue of the American Journal of Physiology published by The American Physiological Society (APS; www.The-APS.org). The study was carried out by Huffman, Douglas R. Moellering, William E. Grizzle, Cecil R. Stockard, Maria S. Johnson and Tim R. Nagy, all of the University of Alabama-Birmingham (UAB) and funded by the UAB Center for Aging. Dr. Huffman is now at the Albert Einstein College of Medicine in New York.

The study built upon previous studies that showed:

  • Rats that exercise regularly will, on average, live longer compared to a group that eats the same amount but does not exercise. This is because exercise prevents some diseases, which allows more individual animals to live out their expected life span.

  • However, when
    '/>"/>

Contact: Christine Guilfoy
cguilfoy@the-aps.org
301-634-7253
American Physiological Society
Source:Eurekalert

1

GOOD

Page: 1 2 3 4

Related biology news :

1. Negligent, attentive mouse mothers show biological differences
2. Scientists successfully treat new mouse model of inflammatory bowel disease
3. Book is the first high-resolution digital mouse brain atlas designed for Web applications
4. Dissecting the genetic components of adaptation of E. coli to the mouse gut
5. CSHL scientists identify and repress breast cancer stem cells in mouse tissue
6. New chimeric mouse model for human liver diseases, drug testing
7. Looking through the eyes of a mouse, scientists monitor circulating cells in its bloodstream
8. Cancer-resistant mouse discovered
9. Immune cells promote blood vessel formation in mouse endometriosis
10. A computer for your mouse!
11. Smithsonian study: Sediment prediction tools off the mark

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/6/2009)...rally live in harmony with their arboreal hosts. B... space in their trees of choice, the ants can get ..., published in the November issue of the American...ore into live trees, and it reopens a centuries-ol...ts. , Ants and certain species of plants and tre...
(Date:11/5/2009)...n of Biology Teachers (NABT) will recognize Leonar...t Naugatuck Valley Community College (NVCC) in Wat...tion Award during the NABT annual professional dev... in Denver, Colorado. , The Evolution Education ...Biological Sciences,(AIBS) and Biological Science...
(Date:11/4/2009)...scientists are reluctant to officially endorse gre...tinues to grow about its protective effects, inclu...revention Research , a journal of the American Ass...reduction in oral cancer. , Vassiliki Papadimit...rtment of Thoracic/Head and Neck Medical Oncology ...
Breaking Biology News(10 mins):Ants are friendly to some trees, but not others 2Biologists, educators recognize excellence in evolution education 2Does green tea prevent cancer? Evidence continues to brew, but questions remain 2Chicago Bears Quarterback Jay Cutler Eli Lilly and Company and the American Diabetes Association Team Up to Fund Diabetes Camp Scholarships Through 56922 1Chicago Bears Quarterback Jay Cutler Eli Lilly and Company and the American Diabetes Association Team Up to Fund Diabetes Camp Scholarships Through 56922 2Chicago Bears Quarterback Jay Cutler Eli Lilly and Company and the American Diabetes Association Team Up to Fund Diabetes Camp Scholarships Through 56922 3Chicago Bears Quarterback Jay Cutler Eli Lilly and Company and the American Diabetes Association Team Up to Fund Diabetes Camp Scholarships Through 56922 4Air Quality Sciences Achieves Re Accreditation as the US Indoor Air Quality Testing Partner for Europes Coveted Blue Angel Program 56918 1Air Quality Sciences Achieves Re Accreditation as the US Indoor Air Quality Testing Partner for Europes Coveted Blue Angel Program 56918 2Air Quality Sciences Achieves Re Accreditation as the US Indoor Air Quality Testing Partner for Europes Coveted Blue Angel Program 56918 3Blue Cross and Blue Shield Sued by Health Care Providers for Abusive Practices 56915 1Blue Cross and Blue Shield Sued by Health Care Providers for Abusive Practices 56915 2Blue Cross and Blue Shield Sued by Health Care Providers for Abusive Practices 56915 3
...up of signaling proteins known as Wnt - which help...r tissues - depend on a complex delivery and recyc...ilding cell sites, according to a study at Cincinn...cycling system - the Retromer Complex - breaks dow...aling proteins fails as their transport vehicle, a...
... 19, 2007) Thailands Western Forest Complex a 6,... of parks and wildlife reserves can potentially s...lds strongholds for these emblematic big cats, acc...ational Park, Wildlife, and Plant Conservation and... The study, which appears in latest issue of the ...
...mmercial materials, lighter and cheaper is usually...led with superior strength and special properties,...inal shape after it,s been deformed by a physical ... as "magnetic shape-memory foams" has been develop... Boise State University and David Dunand at Northw...
Other Biology News:Certain diseases, birth defects may be linked to failure of protein recycling system 2Study says 2000 tigers possible in Thailand 2Metal foam has a good memory 2
(Date:11/9/2009)...the top 10 pharmaceutical giants use Datafarm for ...nada. Datafarm’s announcement comes on the h...Meeting where Health Canada stated that, effective...eCTD regulatory submissions for New Drug Submissio...est. , Marlborough, MA (P...
(Date:11/7/2009)...RNewswire/ -- Research projects in the areas of ma...vening, as Tim Kunisky of Livingston, NJ and the t...on, PA received the highest honors at the Region F..., Science & Technology, the nation,s premier h...w.newscom.com/cgi-bin/prnh/20070904/SIEMENSLOGO ...
(Date:11/6/2009)...r 6 EUCODIS Bioscience, a company,...ing enzymes for the,chemical industry announced to...with Bio Sidus, the leading biopharmaceutical comp...es EUCODIS Bioscience exclusive access - for the s...ietary collection of,psychrophilic bacteria strain...
(Date:11/6/2009)...da for Arrowhead’s 2010 Personalized Medicin...ace on February 22-24, 2010 in Philadelphia, has b...l highlight key issues in forming partnerships and...es. , Minneapolis, MN (PR...rsquo;s 2010 Personalized Medicine Partnerships C...
Breaking Biology Technology:Datafarm Responds to Health Canada's Announcement of Hybrid eCTD Submission Procedural Simplification 2Mathematics and Biochemistry Research Earn Top Prize at Nation's Premier High School Science Competition 2Mathematics and Biochemistry Research Earn Top Prize at Nation's Premier High School Science Competition 3Mathematics and Biochemistry Research Earn Top Prize at Nation's Premier High School Science Competition 4Mathematics and Biochemistry Research Earn Top Prize at Nation's Premier High School Science Competition 5Mathematics and Biochemistry Research Earn Top Prize at Nation's Premier High School Science Competition 6EUCODIS Bioscience to Explore Novel Enzymatic Activities in Antarctic Bacteria Library From Bio Sidus 2Leaders in Biopharma and Molecular Diagnostics to Discuss Key Issues and Opportunities in Forming Partnerships at 2010 Personalized Medicine Partnerships Conference 2Leaders in Biopharma and Molecular Diagnostics to Discuss Key Issues and Opportunities in Forming Partnerships at 2010 Personalized Medicine Partnerships Conference 3
...WALTHAM, Mass., Dec. 21 Inverness Medical,Innovat...as completed its,previously announced acquisition ...ed in New Jersey, is a leading provider of innovat...es and expert coaching to facilitate,better health...tients,including neonatal intensive care and oncol...
...Leading-edge radiation treatment facility to serve...upport by Washington Sen.,Patty Murray and the wes...,resulted in $2.1 million in federal funding desig...oton-beam therapy center by the Seattle Cancer Car...08 Omnibus Appropriations,bill signed by President...
...Majority of Warrant Holders Subscribe to Offering,...in Board: IAGX), announced today that 53 warrants ...til October 23, 2010 in response to the,offering. ...00 to $2.00., The warrants holder,s paid the Comp...ting in the Company receiving, approximately $155,...
Other Biology Technology:Murray Leads Delegation in Securing $2.1 Million for Proton Therapy Center 2Murray Leads Delegation in Securing $2.1 Million for Proton Therapy Center 3Imagenetix Reports Results of Offer to Extend Warrants 2
ELISpot Blue Color Module (Strep-AP and BCIP-NBT) from R&D Systems
Canine IFN-gamma ELISpot Development Kit from R&D Systems
CoverWell imaging chamber gasket with adhesive, one chamber, 20 mm diameter, 1.0 mm deep *set of 40* from Molecular Probes (Invitrogen)
Equine TNF ALPHA from AbD Serotec
Biology Products: