Navigation Links
Mouse brain seen in sharpest detail ever
Date:10/25/2010

DURHAM, N.C. The most detailed magnetic resonance images ever obtained of a mammalian brain are now available to researchers in a free, online atlas of an ultra-high-resolution mouse brain, thanks to work at the Duke Center for In Vivo Microscopy.

In a typical clinical MRI scan, each pixel in the image represents a cube of tissue, called a voxel, which is typically 1x1x3 millimeters. "The atlas images, however, are more than 300,000 times higher resolution than an MRI scan, with voxels that are 20 micrometers on a side," said G. Allan Johnson, Ph.D., who heads the Duke Center for In Vivo Microscopy and is Charles E. Putman Distinguished Professor of Radiology.

The interactive images in the atlas will allow researchers worldwide to evaluate the brain from all angles and assess and share their mouse studies against this reference brain in genetics, toxicology and drug discovery.

The brain atlas' detail reaches a resolution of 21 microns. A micron is a millionth of a meter, or 0.00003937 of an inch.

An article detailing the creation of the atlas was published as the cover story in the November issue of NeuroImage journal.

The atlas used three different magnetic resonance microscopy protocols of the intact brain followed by conventional histology to highlight different structures in the reference brain. The brains were scanned using an MR system operating at a magnetic field more than 6 times higher than is routinely used in the clinic. The images were acquired on fixed tissues, with the brain in the cranium to avoid the distortion that occurs when tissues are thinly sliced for conventional histology.

The new Waxholm Space brain can be digitally sliced from any plane or angle, so that researchers can precisely visualize any regions in the brain, along any axis without loss of spatial resolution. (Waxholm is the Swedish town where the early concepts gelled for this atlas.)

"Researchers c
'/>"/>

Contact: Mary Jane Gore
mary.gore@duke.edu
919-660-1309
Duke University Medical Center
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Exposure to low doses of BPA alters gene expression in the fetal mouse ovary
2. Scientists reprogram mouse fat cells into clinically useful stem cells
3. Mouse stem cell study offers new insights into body fat distribution
4. Scientists create 3-D models of whole mouse organs
5. UCSF transgenic mouse mimics Parkinsons earliest symptoms
6. Intentional variation increases result validity in mouse testing
7. Mouse work: New insights on a fundamental DNA repair mechanism
8. Stem cells restore sight in mouse model of retinitis pigmentosa
9. Penn biologists determine microRNA activity is suppressed in mouse ovum
10. CCNY biologists identify new spiny pocket mouse species
11. Chloride increases response to pheromones and odors in mouse sensory neurons
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Mouse brain seen in sharpest detail ever
(Date:3/30/2015)... DUBLIN , Mar. 26, 2015 Research and ... addition of the "Global Gesture Recognition Market in ... The analysts forecast the Global Gesture Recognition market ... 12.8% over the period 2013-2018. Gesture recognition ... respond to different gestures of an individual. Gesture recognition ...
(Date:3/24/2015)... GARDENS, Fla. , March 24, 2015 /PRNewswire/ ... identity management solutions, today announced that its U.are.U ... clothing accessory retailer Goorin Bros . to ... Crossmatch biometrics-based solution secures access to the POS ... the increased risk of data breaches. ...
(Date:3/20/2015)... Research and Markets ( http://www.researchandmarkets.com/research/4stcg3/india_sensors ... "India Sensors Market Forecast and Opportunities 2020" ... market is projected to grow at a CAGR ... automotive, industrial and healthcare sectors are the key ... addition, adoption of MEMS technology in sensors is ...
Breaking Biology News(10 mins):Global Gesture Recognition Market in Automotive Sector Report 2015 - Growing Number of Partnerships 2Crossmatch Fingerprint Readers Help Retailer Prevent Data Breaches at Point-of-Sale 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 2India Sensors Market Forecast and Opportunities 2020 - STMicroelectronics held the largest share in 2014 3
... Geosphere articles posted online 16 July 2012 include ... Earth,s Surface: Applications of Airborne and Terrestrial LiDAR in ... Southern Alaskan Orogen"; and "Origin and Evolution of the ... California; Cofre de Perote volcano, Mexico; Mammoth Mountain and ...
... Department of the Navy has initiated a project designed ... The tree is called fadang by the region,s indigenous ... known as cycads. Cycads are represented by about 300 ... of plants worldwide. "This will be the first cycad ...
... , WASHINGTON, D.C., JULY 17, 2012 -- What is the ... discoveries and new insights that lead to innovations like the ... entire new industries like biotechnology. It is also the ... of this research who are among the most capable ...
Cached Biology News:Geosphere: How geology, technology, modeling, and mapping see into Earth's past and present 2Geosphere: How geology, technology, modeling, and mapping see into Earth's past and present 3Geosphere: How geology, technology, modeling, and mapping see into Earth's past and present 4Geosphere: How geology, technology, modeling, and mapping see into Earth's past and present 5Geosphere: How geology, technology, modeling, and mapping see into Earth's past and present 6Guam conservation efforts progress 2New video series highlights the people who fuel America's innovation pipeline 2New video series highlights the people who fuel America's innovation pipeline 3
(Date:5/6/2015)... 2015 Park Systems , world-leader ... only high vacuum AFM system in the market that ... semiconductor manufacturing. Park NX-Hivac is ideal for academic and ... in highly doped semiconductor processing where more highly sophisticated ... high vacuum scanning spreading resistance microscopy (SSRM) of Park ...
(Date:5/5/2015)... MD (PRWEB) May 05, 2015 RURO, ... provider released FreezerPro® version 7, the latest major content ... software., Upgrade is a significant ... UI succeeds in enhancing users experience, while also simplifying ... performance, reduces system requirements , Download available ...
(Date:5/5/2015)... May 05, 2015 VetStem Biopharma, ... Animal Health, Jeffrey Schaffer, DVM, as Director of ... 15 years of experience in the veterinary regenerative ... addition to our veterinarian lead organization”. Dr. ... “Dr. Schaffer will be responsible for all technical ...
(Date:5/5/2015)... The Academy of Model Aeronautics is pleased ... Indiana Gov. Mike Pence, has declared August 15, 2015, ... a Family Fest and aviation themed Motorcycle Rally in ... Wounded Warrior Project. , National Model Aviation Day has ... foremost organization for model aviation—to celebrate the history of ...
Breaking Biology Technology:Park Systems Introduces Park NX-Hivac, a High Vacuum SSRM AFM System for Optimal Results in Semiconductor Manufacturing Failure Analysis 2Park Systems Introduces Park NX-Hivac, a High Vacuum SSRM AFM System for Optimal Results in Semiconductor Manufacturing Failure Analysis 3RURO Releases version 7 of FreezerPro® software 2Leading Regenerative Veterinary Medicine Company, VetStem Biopharma announces the addition of Dr Jeffrey Schaffer as the Director of Veterinary Professional Services. 2State of Indiana proclaims August 15 as Model Aviation Day 2
... of thermoelectric effects at graphene contacts, University of Illinois ... effect that reduces their temperature. Led by mechanical ... computer engineering professor Eric Pop, the team will publish ... of the journal Nature Nanotechnology . The ...
... high resolution structure of a nano-scale square made from ribonucleic ... in this week,s early online edition of the journal ... team of chemists headed by Thomas Hermann, an assistant professor ... the ability to carry structural information encoded in the sequence ...
... Cellectis (Alternext: ALCLS), the genome engineering specialist, has announced today ... company covering certain uses of its homologous recombination technology patents ... This agreement has triggered an immediate payment of euro 3M ... have not been disclosed. About Cellectis ...
Cached Biology Technology:Self-cooling observed in graphene electronics 2
... 50 purifications. Allows rapid purification of ... of unincorporated CyDye label and primers ... of labeled cDNA probe. Excellent ... by either direct incorporation or by ...
Detects caspase activation by flow cytometry....
Apoptosis Detection Systems and Reagents...
Anti-Mouse Qa.m7, Ascites (Clone 5035-50.1) (mouse IgM)...
Biology Products: