Navigation Links
Mount Sinai researchers say new strain of bird flu packs a punch even after becoming drug-resistant
Date:12/11/2013

ugh H7N9 appears to have a limited ability to spread readily from human to human, transmissibility in animal models was comparable between drug-susceptible and drug-resistant strains. "Transmission was inefficient for both of the H7N9 viruses that we tested in our experiments," said Dr. Bouvier. "But surprisingly, transmission of the drug-resistant virus was no less efficient than that of the drug-sensitive version."

"Many of the people infected with H7N9 during the outbreak in China were elderly or had other conditions that predisposed them to severe influenza illness," observed Dr. Bouvier. "Nevertheless, our study suggests that flu viruses can indeed develop drug-resistant mutations without suffering a penalty in terms of their own fitness."

Older antiviral drugs such as amantadine are no longer effective in treating most strains of the flu that infect humans. Newer antiviral drugs called neuraminidase inhibitors block an enzyme that helps the virus replicate. These drugs include Tamiflu, a pill, and Relenza (zanamivir), a powder that is inhaled. Both medications have drawbacks: flu viruses can develop resistance to the medications in people who take them, and, in many parts of the world, neither drug is available in an intravenous form to treat those with severe infections.

"Our study underscores the need to develop a bigger arsenal of antiviral drugs and vaccines, which will allow us to outsmart the influenza virus," said Dr. Bouvier. "Researchers at Mount Sinai are actively engaged in identifying new targets for drug therapy and are working to develop a universal vaccine that will prevent multiple strains of influenza."


'/>"/>

Contact: Sid Dinsay
sid.dinsay@mountsinai.org
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine
Source:Eurekalert

Page: 1 2

Related biology news :

1. UNH research adds to mounting evidence against popular pavement sealcoat
2. Expedition to undersea mountain yields new information about sub-seafloor structure
3. CU research shows warming climate threatens ecology at mountain research site west of Boulder
4. Accelerating climate change exerts strong pressure on Europes mountain flora
5. Global warming has driven Europes mountain plants to migrate 2.7 meters upwards in 7 years
6. European mountain plant population shows delayed response to climate change
7. Medbox Developing a Patent Pending Wall-Mounted Biometric Kiosk for Storage of Sensitive Medicine Samples and Supplies for Doctors Offices.
8. Nitrogen pollution changing Rocky Mountain National Park vegetation, says CU-Boulder-led study
9. NCEAS DataONE streamlines search and analysis of massive amounts of ecological data
10. Mount Sinai researchers solve mystery surrounding the death of two sisters nearly 50 years ago
11. IdentiSys acquires the Identification, Security and Presentation Divisions of Mountainland Business Systems, a Utah based reseller
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... , June 27, 2014  The American Academy ... Institute of Standards and Technology (NIST) and the ... academic research and forensic science expert members to ... is an element of the NIST,s Organization of ... among the first appointments made to the new ...
(Date:7/10/2014)... N.Y. , July 2, 2014 It ... (ABD) to announce the appointment of the world-renowned Thoracic ... Board of Directors. Dr. Ginsburg, with over ... facilities: NY Presbyterian Hospital and Good Samaritan Regional Medical ... Pacemaker since the late 1980,s and is considered an ...
(Date:7/10/2014)... 7, 2014 According to a ... Access Control Systems Market Global Forecast, Market Share, Size, ... Electronic Access Control systems market was valued at USD ... at a CAGR of 12.6% from 2014 to 2019, ... in 2019. Browse the full Electronic Access ...
Breaking Biology News(10 mins):Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 3Avery Biomedical Devices, Inc. announces the appointment of Mark E Ginsburg, M.D. to its Board of Directors 2Electronic Access Control Systems Market is Expected to Reach USD 31.2 Billion Globally in 2019: Transparency Market Research 2Electronic Access Control Systems Market is Expected to Reach USD 31.2 Billion Globally in 2019: Transparency Market Research 3Electronic Access Control Systems Market is Expected to Reach USD 31.2 Billion Globally in 2019: Transparency Market Research 4Electronic Access Control Systems Market is Expected to Reach USD 31.2 Billion Globally in 2019: Transparency Market Research 5
... 1980s, the idea has become predominant that the best ... value for it in the framework of markets. The ... offered a glimpse of many possibilities for money-earning uses ... the Convention on Biological Diversity, a measure adopted in ...
... Helios Education Foundation today awarded $6.5 million to the ... new partnership that extends the Helios Scholars Program at ... cultivate new scientific and technical talent across the state ... a long term partnership with TGen for student training ...
... to count monkeys? To Tasmania to track devils Down Under? ... No worries, theres a field guide for you, in ... but mostly practical field guides to all matter of, ... English churchyard lichens. Diane Schmidt, the biology librarian at ...
Cached Biology News:Markets of biodiversity and equity in trade: An illusion? 2Markets of biodiversity and equity in trade: An illusion? 3Helios Education Foundation invests $6.5 million 2Helios Education Foundation invests $6.5 million 3U. of I. librarian launches comprehensive Web database of field guides 2U. of I. librarian launches comprehensive Web database of field guides 3
(Date:7/10/2014)... research may help in the fight against terrorism with ... quantities of explosives with the use of light and ... Sensors and Actuators B: Chemical , the researchers describe ... in concentrations as low as 6.3 ppm (parts per ... few minutes. , "Traditionally explosives detection has involved looking ...
(Date:7/10/2014)... The lithium-ion batteries that power our laptops and ... on a single charge with the help of a ... material to replace the graphite traditionally used in one ... 10 times the energy storage capacity of graphite. A ... electrode was published today in Nature Communications . ...
(Date:1/15/2014)... assembling a club sandwich at the nanoscale, National ... succeeded in crafting a uniform, multi-walled carbon-nanotube-based coating ... used in upholstered furniture and other soft furnishings. ... was reduced 35 percent compared with untreated foam. ...
(Date:1/15/2014)... 2014 Look inside the new Preferred ... the lab, from fluid handling to instruments to supplies. ... when you order. , Preferred Solutions features a ... the L/S® model for precise flow control and dispensing ...
Breaking Biology Technology:Detecting trace amounts of explosives with light 2Silicon sponge improves lithium-ion battery performance 2Silicon sponge improves lithium-ion battery performance 3Layered security: Carbon nanotubes promise improved flame-resistant coating 2Cole-Parmer Begins 2014 with the Release of Preferred Solutions 2
... BioLife Solutions, Inc.,(OTC Bulletin Board: BLFS), a ... storage and cryopreservation media products for cells,tissues, ... joined the Biomedical,Excellence for Safer Transfusion (BEST) ... and commercial partners whose,mission is to explore ...
... AlloSource, one of the nation,s largest non-profit providers of ... surgical procedures, will this year sponsor one of the ... in the January 1 Tournament of Roses Parade(R). The ... to the millions of people touched by organ, tissue ...
... California (USC) have, for the first time in history, derived ... will enable scientists to create far more effective animal models ... , The research will be published in the Dec. 26 ... is a major development in stem cell research because we ...
Cached Biology Technology:BioLife Solutions Joins Prestigious Biomedical Excellence for Safer Transfusion Collaborative 2BioLife Solutions Joins Prestigious Biomedical Excellence for Safer Transfusion Collaborative 3AlloSource, Tissue Recipient Join 'Stars of Life' Affected by Organ and Tissue Donation Aboard Donate Life Float in 2009 Rose Parade(R) 2AlloSource, Tissue Recipient Join 'Stars of Life' Affected by Organ and Tissue Donation Aboard Donate Life Float in 2009 Rose Parade(R) 3USC researchers derive first embryonic stem cells from rats 2USC researchers derive first embryonic stem cells from rats 3
One-step, microplate or cuvet, colorimetric, linear detection range 0.6 mM to 100 mM. Procedure: 2 min....
assays for phosphatase, lipase, nucleoside triphosphatases (ATPase, GTPase etc). HTS and follow up studies for phosphatase inhibitors. Quantitation of phosphate content in protein, lipids, and DNA....
... Design with Purpose -- ... MS provide the highest level ... performance in an affordable, easy-to-use ... autosampler and workstation guarantees success ...
Homo sapiens 4-aminobutyrate aminotransferase Antigen: Recombinant Protein...
Biology Products: