Navigation Links
Motor Neurone Disease Association study identifies MND biomarker
Date:11/4/2010

A study funded by the Motor Neurone Disease (MND) Association, in collaboration with the Medical Research Council (MRC), has identified a common signature of nerve damage in the brains of MND patients.

The study's exciting findings have been published in the prestigious journal Neurology (2 November 2010). These are the first results to be published from the ongoing Oxford Study for Biomarkers in MND/ALS (BioMOx).

MND research is being held back by the lack of an early diagnostic test and predictable markers of the progression of the disease biomarkers. Patients still wait too long for a certain diagnosis of MND and clinical trials are hampered by lengthy study times and variability of the disease between people living with MND. If MND biomarkers can be identified then they could dramatically improve the speed and accuracy with which MND can be diagnosed, and how future treatments are assessed.

This study used an advanced magnetic resonance imaging (MRI) technique, to look for areas of the brain that are universally damaged in patients with MND as compared to healthy controls. From this, Dr Martin Turner and colleagues at the University of Oxford found a unique similarity of nerve damage in a region of the brain that connects the motor neurones to the brain as well as damage to a region that acts as a connection between the left and right sides of the brain known as the 'corpus callosum'.

Talking about the study findings, Dr Martin Turner says: "The finding of a common pattern of nerve pathway damage in a varied group of MND patients holds the promise of a much needed biomarker.

"This study confirms the ability of advanced MRI techniques to sensitively detect nerve damage in a wide range of people living with MND. It builds on a decade of international work, and shows that MRI is now a frontrunner in the quest to generate biomarkers of disease activity in MND."

Dr Brian Dickie, director of research develo
'/>"/>

Contact: Louise Coxon
louise.coxon@mndassociation.org
01-604-611-843
Motor Neurone Disease Association
Source:Eurekalert

Page: 1 2

Related biology news :

1. Motorola Introduces Mobile Biometric Identification for Handheld Computers
2. SAFRAN to Acquire Motorolas Biometrics Business
3. Motor nerve targeting to limb muscles is controlled by ephrin proteins
4. Biologists learn structure, mechanism of powerful molecular motor in virus
5. Microbot motors fit to swim human arteries
6. UCLA stem cells scientists make electrically active motor neurons from iPS cells
7. First neuroimaging study examining motor execution in children with autism reveals new insights
8. Researchers design first model motor nerve system thats insulated and organized like the human body
9. Atomic-level snapshot catches protein motor in action
10. New study possibly links cognitive and motor delays with flat head syndrome in young babies
11. Lifes smallest motor, cargo carrier of the cells, moves like a seesaw
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... use a previously unknown process for harvesting energy and ... a Penn State University scientist has discovered. The discovery ... plant growth, harvesting energy from the Sun, and understanding ... and other lakes worldwide. A paper describing the discovery ... edition of the journal Science on 21 ...
(Date:8/21/2014)... linked to dandruff, eczema and other itchy, flaky maladies ... global reachesincluding Hawaiian coral reefs and the extreme environments ... review in the scientific journal PLOS Pathogens ... of the genus Malassezia in light of ... around the world. , University of Hawai,i at Mānoa ...
(Date:8/21/2014)... aimed at improving the food intake, health and quality ... is among three projects at the University of Waterloo ... Canadian Institutes of Health Research (CIHR). , Professor ... at Waterloo, and a Schlegel research chair in nutrition ... investigate why many Canadians living in long-term care homes ...
Breaking Biology News(10 mins):Hot-spring bacteria reveal ability to use far-red light for photosynthesis 2Hot-spring bacteria reveal ability to use far-red light for photosynthesis 3From dandruff to deep sea vents, an ecologically hyper-diverse fungus 2Grants will fund landmark aging research at Waterloo 2
... N.Y. and MUNICH, Nov. 7, 2012 Bausch + Lomb, the ... its option to purchase all outstanding and unowned shares of ... laser company. Technolas Perfect Vision was established in ... 20/10 PERFECT VISION AG to develop and sell advanced refractive ...
... drug, geldanamycin, is well known for attacking a protein ... laboratory-based study found it also degraded a different protein ... vessel growth is a key challenge in the battle ... human disease biology in the University of Leeds, Faculty ...
... (Philadelphia, PA) When a person has a heart attack, ... days or even weeks if deprived of oxygen for long ... growth of new blood vessels, in an attempt to regain ... remodeling is actually harmful, and the damaged heart is on ...
Cached Biology News:Bausch + Lomb to Acquire Technolas Perfect Vision GmbH 2Bausch + Lomb to Acquire Technolas Perfect Vision GmbH 3Breast cancer drug could halt other tumors 2Losing protein helps heart recover, say Temple scientists 2Losing protein helps heart recover, say Temple scientists 3
(Date:8/21/2014)... at the Institute for Molecular Medicine Finland (FIMM), ... developed a novel "man and machine" decision support ... aid was described in PLOS One ... based on computer vision algorithms similar to those ... of only the diagnostically most relevant areas. Tablet ...
(Date:8/21/2014)... COLD SPRING, N.Y. , Aug. 21, 2014 ... today the launch of their Nutraceutical "TELO-20 for ... first and only Telomere-lengthening supplement in the world ... the ends of every chromosome in the body. ... the world,s leading experts in Telomere Science and ...
(Date:8/21/2014)... Aug. 21, 2014  China Cord Blood Corporation (NYSE: ... to release financial results for the first quarter of ... market close in the US.  The ... ET on Friday, August 29, 2014 to discuss its ... Company,s recent developments, followed by a question and answer ...
(Date:8/21/2014)... (PRWEB) August 21, 2014 ... has been recognized as one of the nation’s ... 5000 magazine for the 2nd consecutive year. Inc. ... 33rd annual Inc. 500|5000, an exclusive ranking of ... the most comprehensive look at the most important ...
Breaking Biology Technology:A novel 'man and machine' decision support system makes malaria diagnostics more effective 2Telomere Biosciences Announces: TELO-20 for Dogs, the World's First Telomere-Lengthening Supplement for Dogs, to Promote Healthy Aging and Longevity 2Telomere Biosciences Announces: TELO-20 for Dogs, the World's First Telomere-Lengthening Supplement for Dogs, to Promote Healthy Aging and Longevity 3China Cord Blood Corporation to Report First Quarter of Fiscal 2015 Financial Results 2SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 2SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 3
... With Trellis-8 Catheter From Bacchus Vascular, Reducing ... ... Calif., March 6 Bacchus Vascular Inc., a,leading provider of ... cardiologists for the,minimally invasive treatment of deep vein thrombosis (DVT) ...
... 5 /PRNewswire-FirstCall/ - Dragon Pharmaceutical Inc.,("Dragon" or ... DRP), a leading,international pharmaceutical company today announced ... for its core products 7ACA and,Clavulanic Acid ... to meet increasing,demand from its customers. Meanwhile, ...
... This release is available in German . ... individual organs, our cells themselves are made of tiny ... tasks. Such functional, nanostructured systems would also be useful ... components, or nanocapsules. However, it has not been possible ...
Cached Biology Technology:Major Medical Journal Reports Higher Success, Fewer Complications and Lower Cost Treating DVT With Trellis(R) Isolated Thrombolysis Compared With Catheter-Directed Thrombolysis 2Dragon announces new product launch; increase in annual production output capacity 2Dragon announces new product launch; increase in annual production output capacity 3Dragon announces new product launch; increase in annual production output capacity 4Cellular construction methods emulated 2
... you reduce the chance of error. Thats ... Developed using Beckman Coulters extensive experience in ... technology, the CEQ 8000 is a fully ... fills the capillary array with a patented ...
... Chemicon Detergent-OUT Kit is a simple high ... solutions. Removes detergents without significant dilution ... protein solution on the Detergent-OUT Spin column ... columns are suitable for removing detergent from ...
... The standard electrophoresis hood is ... documentation systems. Placed on the ... in place and provides a ... on the lab bench. This ...
... SDS Kit is a simple high performance ... Removes detergents without significant dilution of ... solution on the Detergent-OUT Spin column and ... columns are suitable for removing detergent from ...
Biology Products: