Navigation Links
Mother's BMI linked to fatter babies
Date:8/19/2011

Babies of mothers with a higher pre-pregnancy body mass index (BMI) are fatter and have more fat in their liver, a study published in September's issue of the journal Pediatric Research has found. The researchers from Imperial College London say that the effect of a mother's BMI on her child's development in the womb might put them on a trajectory towards lifelong metabolic health problems.

The research team used magnetic resonance scanning to assess 105 babies born at Chelsea and Westminster Hospital. The babies were scanned while they were asleep to measure the amount of fat in their liver cells, the total amount of fat in their bodies and its distribution. They found that liver cell fat in the babies and total fat, particularly around the abdomen, increased across the entire range of BMI in their mothers.

Children of overweight and obese mothers are already known to have a higher risk of being overweight and obese themselves, and of experiencing associated metabolic health problems such as type-2 diabetes. The authors of this new study suggest that the changes they found in babies' bodies might be signs of the first biological changes which, combined with an unhealthy lifestyle, might put babies of overweight mothers on a path to ill health in later life.

Professor Neena Modi, from the Department of Medicine at Imperial College London and a Consultant Neonatologist at Chelsea and Westminster Hospital, who led the study, said: "This study demonstrates that a woman's BMI, even in the normal range, affects the amount of fat in her baby at birth. Fatter women have fatter babies and there is more fat in the babies livers. If these effects persist through childhood and beyond, they could put the child at risk of lifelong metabolic health problems.

"There is growing evidence that a baby's development before birth has a major impact on their health in later life. This means that the prevention of obesity needs to begin in the womb.

"Today about half of all women of childbearing age in the UK are overweight or obese. Importantly, the link between maternal BMI and amount of fat in the baby spreads across the entire range of BMI, meaning it's not just an issue for overweight and obese mums. We need to identify what the optimal BMI for the mother is so we can help women ensure that their bodies are in the best possible condition before they get pregnant."

Body mass index is calculated by dividing one's weight in kilograms by the square of their height in metres. The World Health Organisation classes a BMI between 18.5 and 25 as normal weight, between 25 and 30 as overweight and over 30 as obese. Of the 105 mothers in the study, five were underweight, 69 were normal weight, 23 were overweight and eight were obese.

The researchers used proton magnetic resonance imaging and spectroscopy to measure total adipose tissue and its distribution and intrahepatocellular lipid (the amount of fat inside liver cells). In adults, high levels of both correlate strongly with impaired control of blood sugar.


'/>"/>

Contact: Sam Wong
sam.wong@imperial.ac.uk
44-207-594-2198
Imperial College London
Source:Eurekalert

Related biology news :

1. Children of depressed mothers have a different brain
2. New mothers can learn a lot from watching their babies
3. Parenting stress affects new mothers’ postpartum lifestyle
4. Preterm mothers milk contains less antioxidants than mothers completing their gestation
5. Mothers diets have biggest influence on children eating healthy
6. New report suggests why risk for sudden infant death syndrome is greater in babies of mothers who smoke
7. Successful mothers get help from their friends: Dolphin study
8. Discus fish parent young like mammalian mothers
9. Black mothers cite lack of desire as top reasons for not breastfeeding
10. About 94 percent of breastfeeding mothers do not follow a proper diet
11. Giving DHA supplements to breastfeeding mothers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2017)...  Socionext Inc., a global expert in SoC-based imaging and computing ... M820, which features the company,s hybrid codec technology. A demonstration utilizing ... Inc., will be showcased during the upcoming Medtec Japan at Tokyo ... Las Vegas Convention Center April 24-27. ... Click here for an image ...
(Date:4/11/2017)... Research and Markets has announced the addition of the ... ... grow at a CAGR of 30.37% during the period 2017-2021. ... prepared based on an in-depth market analysis with inputs from industry ... over the coming years. The report also includes a discussion of ...
(Date:4/5/2017)... Today HYPR Corp. , leading innovator ... of the HYPR platform is officially FIDO® Certified ... architecture that empowers biometric authentication across Fortune 500 enterprises ... over 15 million users across the financial services industry, ... product suites and physical access represent a growing portion ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... They call it ... biological network, a depiction of a system of linkages and connections so complex ... associate professor of computer science at Worcester Polytechnic Institute (WPI) and director of ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... of a United States multicenter, prospective clinical study that demonstrates the accuracy ... test capable of identifying clinically significant acute bacterial and viral respiratory tract ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... genomics analysis platform specifically designed for life science researchers to analyze and ... researcher Rosalind Franklin, who made a major contribution to the discovery of ...
(Date:10/11/2017)... ... ... Personal eye wash is a basic first aid supply for any work environment, but most ... you rinse first if a dangerous substance enters both eyes? It’s one less decision, and ... unique dual eye piece. , “Whether its dirt and debris, or an acid or alkali, ...
Breaking Biology Technology: