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Most clinical studies on vitamins flawed by poor methodology
Date:12/30/2013

vitamins have been done with groups such as doctors and nurses who are educated, informed, able to afford healthy food and routinely have better dietary standards than the public as a whole," said Frei, an international expert on vitamin C and antioxidants.

"If a person already has adequate amounts of a particular vitamin or nutrient, then a supplement will probably provide little or no benefit," Frei said. "That's common sense. But most of our supposedly scientific studies take results from people with good diets and healthy lifestyles and use them to conclude that supplements are of no value to anyone."

Vitamin or mineral supplements, or an improved diet, will primarily benefit people who are inadequate or deficient to begin with, OSU researchers said. But most modern clinical studies do not do baseline analysis to identify nutritional inadequacies and do not assess whether supplements have remedied those inadequacies. As a result, any clinical conclusion made with such methodology is pretty much useless, they said.

An optimal diet, rich in fruits and vegetables, can provide most of the nutrients needed for good health which critics say is reason enough not to use supplements. LPI researchers say that misses a pretty obvious point that most Americans do not have an optimal diet.

"More than 90 percent of U.S. adults don't get the required amounts of vitamins D and E for basic health," Frei said. "More than 40 percent don't get enough vitamin C, and half aren't getting enough vitamin A, calcium and magnesium. Smokers, the elderly, people who are obese, ill or injured often have elevated needs for vitamins and minerals.

"It's fine to tell people to eat better, but it's foolish to suggest that a multivitamin which costs a nickel a day is a bad idea."

Beyond that, many scientists studying these topics are unaware of ways in which nutrients may behave differently in something like a cell culture or lab animal, com
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Contact: Balz Frei
balz.frei@oregonstate.edu
541-737-5078
Oregon State University
Source:Eurekalert  

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