Navigation Links
Mosquito virus could lead to new vaccines and drugs
Date:9/21/2012

there were two new viruses in the sample. One virus killed insect cells, and the other Eilat virus infected them without doing any harm.

"We were extraordinarily lucky to have that other virus in our sample, because without the cell death it caused, we never would have done the work that led us to Eilat," Nasar said. "Essentially, we found it by accident."

Eilat's inability to grow in animal cells even its genetic material cannot replicate in them makes it unique among alphaviruses, and it also makes it likely that the virus could be uniquely valuable to researchers who study alphaviruses and work to protect humans and domestic animals from them. For example, the UTMB researchers say, Eilat could be transformed into a vaccine against one of its dangerous relatives by making changes to the genes that produce its envelope proteins, which are exposed on virus particle surfaces and stimulate the critical parts of the immune response.

"We have taken the genes for the envelope proteins of very dangerous viruses like eastern equine encephalitis and used them to replace the genes for Eilat's structural proteins," Nasar said. "That gives us viruses that we can grow in insect cells that can't do anything in vertebrate cells at all, but still produce immunity against eastern equine encephalitis they can be used to vaccinate animals, and hopefully someday people."

A variety of Eilat-based "chimeric viruses" viruses made by combining genetic material from other viruses could be used to study the interactions between host cells and dangerous alphaviruses, leading to the development of antiviral drugs. The viruses could also serve as the basis for new diagnostic tools that could be deployed in an alphavirus outbreak. Because these chimeras, like Eilat, would not be able to infect vertebrates, such research could be done without the elaborate and often cumbersome containment precautions needed for working with pathogens like chikungunya, Ve
'/>"/>

Contact: Jim Kelly
jpkelly@utmb.edu
409-772-8791
University of Texas Medical Branch at Galveston
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Mosquitoes -- how we smell is why they bite, research shows
2. New rearing system may aid sterile insect technique against mosquitoes
3. Viruses not to blame for chronic fatigue syndrome after all
4. Study of giant viruses shakes up tree of life
5. Viruses could be the key to healthy corals
6. Computer viruses could take a lesson from showy peacocks
7. By detecting smallest virus, researchers open possibilities for early disease detection
8. Viruses with integrated gene switch
9. Turmeric spices up virus study
10. Scientists discover new type of virus responsible for a devastating disease in snakes
11. Researchers demonstrate control of devastating cassava virus in Africa
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... genes to the earliest common ancestor of butterflies ... an extensive "Tree of Lepidoptera" in the first ... , Among the study,s more surprising findings: Butterflies ... to large ones, which completely changes scientists, understanding ... that some insects once classified as moths are ...
(Date:7/31/2014)... IL Researchers who studied 100 twin pairs have identified ... normally on less than six hours of sleep per night. ... to the effects of sleep deprivation. , Results show that ... gene had an average nightly sleep duration of only ... the non-carrier twin, who slept for about six hours and ...
(Date:7/31/2014)... completed a 20-year study that looks at the ... times of the year. It finds that burning ... has no measurable negative consequences for the prairie ... The study was conducted by Gene Towne, research ... chief, and Joseph Craine, research assistant professor, both ...
Breaking Biology News(10 mins):UF study advances 'DNA revolution,' tells butterflies' evolutionary history 2UF study advances 'DNA revolution,' tells butterflies' evolutionary history 3Study of twins discovers gene mutation linked to short sleep duration 2Study finds benefits to burning Flint Hills prairie in fall and winter 2Study finds benefits to burning Flint Hills prairie in fall and winter 3
... the Baltic Sea compete for fish with the fishing industry. The ... salmon, sea trout and eel as those taken by fishermen. This ... Gothenburg, Sweden. Competing with the fishing industry , ... species and the same sizes of fish as those taken by ...
... CLEVELAND In a first-of-its-kind clinical trial, physician-scientists ... Center and Case Western Reserve University School of Medicine ... cancer screening. The five-year study is recruiting patients to ... colonoscopy for detecting large colon polyps. ...
... the Nile have found what they believe is the first ... group within the relatively short history of plant domestication. ... in the ancient world and could also help today,s domestic ... The researchers, led by Dr Robin Allaby from the ...
Cached Biology News:Gray seals consume as much fish as the fishing industry catches 2New clinical trial explores novel noninvasive colon cancer screening test 2New clinical trial explores novel noninvasive colon cancer screening test 3Ancient Egyptian cotton unveils secrets of domesticated crop evolution 2Ancient Egyptian cotton unveils secrets of domesticated crop evolution 3
(Date:8/1/2014)... Corporation (NYSE: CBM ) reports results for the ... , Second quarter sales increased 59% to $98.0 ... , Second quarter EBITDA increased 86% to $21.2 million ... (see table at the end of this release). , ... foreign currency, to between 13% and 16% over 2013, and ...
(Date:7/31/2014)... Dallas, Texas (PRWEB) August 01, 2014 ... Global and China Polyurethane Resin Industry” is ... Polyurethane Resin market. The report introduces Polyurethane ... application, and industry chain structure and industry ... analysis, including China’s domestic market as well ...
(Date:7/31/2014)... Alan Turing, the British mathematician (1912-1954), is famous for ... the 20th century. In 1936 he published a paper, ... first formal concept of a computer algorithm. He next ... designing the machines which cracked the German military codes, ... crucial battles. And in the late 1940,s he turned ...
(Date:7/31/2014)... SPRINGS, Colo. , July 31, 2014 /PRNewswire-USNewswire/ ... Grant awardee today with $25,000 to fund a ... Foundation,s inception in 2011, the gift was presented ... th Annual Meeting in Colorado ... who specialize in neurointerventional approaches to neurovascular conditions, ...
Breaking Biology Technology:Cambrex Reports Second Quarter 2014 Financial Results 2Cambrex Reports Second Quarter 2014 Financial Results 3Cambrex Reports Second Quarter 2014 Financial Results 4Cambrex Reports Second Quarter 2014 Financial Results 5Cambrex Reports Second Quarter 2014 Financial Results 6Cambrex Reports Second Quarter 2014 Financial Results 7Cambrex Reports Second Quarter 2014 Financial Results 8Cambrex Reports Second Quarter 2014 Financial Results 9Cambrex Reports Second Quarter 2014 Financial Results 10Cambrex Reports Second Quarter 2014 Financial Results 11Cambrex Reports Second Quarter 2014 Financial Results 12Cambrex Reports Second Quarter 2014 Financial Results 13Cambrex Reports Second Quarter 2014 Financial Results 14Cambrex Reports Second Quarter 2014 Financial Results 15Cambrex Reports Second Quarter 2014 Financial Results 16Polyurethane Resin Industry & Thermoplastic Polyurethane Market (China, Global) Analysis Now at DeepResearchReports.com 2Polyurethane Resin Industry & Thermoplastic Polyurethane Market (China, Global) Analysis Now at DeepResearchReports.com 3Polyurethane Resin Industry & Thermoplastic Polyurethane Market (China, Global) Analysis Now at DeepResearchReports.com 4A mathematical theory proposed by Alan Turing in 1952 can explain the formation of fingers 2A mathematical theory proposed by Alan Turing in 1952 can explain the formation of fingers 3SNIS Foundation Bestows First Grant Award For Cutting-Edge NeuroInterventional Research 2SNIS Foundation Bestows First Grant Award For Cutting-Edge NeuroInterventional Research 3
... and Physical Sciences Research Council (EPSRC) has today announced ... The five-year fellowships, each worth around 1 million, ... Bhaskaran, Dr Ajoy Velayudhan and Dr Peter Foote. ... the manufacturing challenges of tomorrow we need to transfer ...
... president and CEO Michael J. Collins delivered the commencement ... Biochemistry Department, which was held on May 18, 2012. Collins ... has been a member of the Advisory Board for the ... (Logo: http://photos.prnewswire.com/prnh/20090622/CL35336LOGO-b ) "I ...
...  With approximately one in four adults suffering from ... funding and high case loads, the value of ... vital to effective mental health services. ILCs are ... people with physical disabilities, but across the country, ...
Cached Biology Technology:EPSRC announces first recipients of Fellowships in Manufacturing 2CEM President and CEO Delivers Commencement Address at the 2012 University of Texas at Austin Chemistry and Biochemistry Department Graduation 2Peers Underscored As An Effective Counseling Tool 2
MAb to Yersinia pestis F1 Ag. Yersinia pestis F1 Antigen EB Strain...
Mouse monoclonal antibody to QDPR - quinoid dihydropteridine reductase...
... RED Chromogen System consists of FAST RED ... in the presence of alkaline phosphatase to ... The FAST RED System provides enough ... Contains: , , Vial A: 6 Tablets ...
The BioLogic Maximizer mixer is for use with the Maximizer valve system. The mixer improves gradient quality by mixing the output of the BioLogic DuoFlow workstation pumps....
Biology Products: