Navigation Links
Mosquito virus could lead to new vaccines and drugs
Date:9/21/2012

there were two new viruses in the sample. One virus killed insect cells, and the other Eilat virus infected them without doing any harm.

"We were extraordinarily lucky to have that other virus in our sample, because without the cell death it caused, we never would have done the work that led us to Eilat," Nasar said. "Essentially, we found it by accident."

Eilat's inability to grow in animal cells even its genetic material cannot replicate in them makes it unique among alphaviruses, and it also makes it likely that the virus could be uniquely valuable to researchers who study alphaviruses and work to protect humans and domestic animals from them. For example, the UTMB researchers say, Eilat could be transformed into a vaccine against one of its dangerous relatives by making changes to the genes that produce its envelope proteins, which are exposed on virus particle surfaces and stimulate the critical parts of the immune response.

"We have taken the genes for the envelope proteins of very dangerous viruses like eastern equine encephalitis and used them to replace the genes for Eilat's structural proteins," Nasar said. "That gives us viruses that we can grow in insect cells that can't do anything in vertebrate cells at all, but still produce immunity against eastern equine encephalitis they can be used to vaccinate animals, and hopefully someday people."

A variety of Eilat-based "chimeric viruses" viruses made by combining genetic material from other viruses could be used to study the interactions between host cells and dangerous alphaviruses, leading to the development of antiviral drugs. The viruses could also serve as the basis for new diagnostic tools that could be deployed in an alphavirus outbreak. Because these chimeras, like Eilat, would not be able to infect vertebrates, such research could be done without the elaborate and often cumbersome containment precautions needed for working with pathogens like chikungunya, Ve
'/>"/>

Contact: Jim Kelly
jpkelly@utmb.edu
409-772-8791
University of Texas Medical Branch at Galveston
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Mosquitoes -- how we smell is why they bite, research shows
2. New rearing system may aid sterile insect technique against mosquitoes
3. Viruses not to blame for chronic fatigue syndrome after all
4. Study of giant viruses shakes up tree of life
5. Viruses could be the key to healthy corals
6. Computer viruses could take a lesson from showy peacocks
7. By detecting smallest virus, researchers open possibilities for early disease detection
8. Viruses with integrated gene switch
9. Turmeric spices up virus study
10. Scientists discover new type of virus responsible for a devastating disease in snakes
11. Researchers demonstrate control of devastating cassava virus in Africa
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2015)... TRIANGLE PARK, North Carolina , 5. ... sein 35. Jahr als spezialisiertes Logistikunternehmen und ... Position als einzige klinische Logistikfirma (Clinical Logistics ... Die Kernbotschaft der neuen Kampagne lautet ... und Lieferungen. Foto: http://photos.prnewswire.com/prnh/20150205/173753 ...
(Date:2/5/2015)... Jan. 27, 2015   Marvin Test ... deployed, innovative test solutions for military, aerospace, ... of its TS-323 GENASYS Test Platform ... (LMSSC). GENASYS is a high-performance PXI-based system ... applications that require performance functional testing. GENASYS ...
(Date:2/5/2015)...  It is gratifying to see that the Obama ... science as a means to better understand human biology, ... was honored to participate in today,s White House event ... Since the 1980s my teams have been ... sequenced genome of a free living organism, the first ...
Breaking Biology News(10 mins):Marken startet Kampagne mit Patienten im Mittelpunkt 2Marken startet Kampagne mit Patienten im Mittelpunkt 3Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 2Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 3Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 4J. Craig Venter, Ph.D., Co-Founder and CEO, Human Longevity, Inc. (HLI) Participates in White House Precision Medicine Event 2
... Newly diagnosed type 2 diabetics tend to have one ... trigger diabetes has long been the subject of intense ... Marth, Ph.D., director of the Center for Nanomedicine, a ... Sanford-Burnham Medical Research Institute (Sanford-Burnham), has revealed a pathway ...
... COLUMBUS, Ohio Salmonella cells have hijacked ... new research suggests. Scientists say that these bacteria have ... using a beta form of an amino acid as ... making proteins. Beta versions of amino acids occur ...
... Reportlinker.com announces that a new market research report ... Biobanking: Technologies and Global Markets ... THIS REPORT CONTAINS ... types: Population, Disease, and Private Sector ...
Cached Biology News:How fatty diets cause diabetes 2Salmonella stays deadly with a 'beta' version of cell behavior 2Salmonella stays deadly with a 'beta' version of cell behavior 3Biobanking: Technologies and Global Markets 2Biobanking: Technologies and Global Markets 3Biobanking: Technologies and Global Markets 4Biobanking: Technologies and Global Markets 5Biobanking: Technologies and Global Markets 6Biobanking: Technologies and Global Markets 7Biobanking: Technologies and Global Markets 8Biobanking: Technologies and Global Markets 9Biobanking: Technologies and Global Markets 10Biobanking: Technologies and Global Markets 11Biobanking: Technologies and Global Markets 12Biobanking: Technologies and Global Markets 13
(Date:2/27/2015)... FamilyFarms Group is pleased to announce its valued ... received the 2015 Tomorrow’s Top Producer Horizon Award. The ... 35, who has demonstrated excellence in the business of ... Tomorrow's Top Producer Horizon Award. Every year I look ... and learning from their experiences. It is truly humbling ...
(Date:2/27/2015)...  Steep Hill, the industry leader in cannabis testing ... open a full service medical cannabis quality assurance laboratory ... advanced scientific tools and methodology to the state, for ... currently the only laboratory licensed by the New Mexico ... in order to meet the recently adopted regulatory requirements ...
(Date:2/26/2015)... S&P Capital IQ (MHFI) announced today that ... MabVax Therapeutics Holdings Inc . MabVax ... company focused on the development of vaccine and antibody-based ... of cancer. MabVax has discovered a pipeline of human ... generated by patients who have been immunized against targeted ...
(Date:2/26/2015)... VIEW, Calif. , Feb. 26, 2015  23andMe, ... of Kate Black as Privacy Officer and ... federal, and state privacy laws as well as health ... regulatory team, she will be responsible for reviewing, updating ... customers in the U.S. and abroad. She joined the ...
Breaking Biology Technology:Matt Sims Receives the 2015 Tomorrow’s Top Producer Horizon Award 2Steep Hill First to Receive Provisional Approval to Establish Laboratory Services for Cannabis Testing in State of New Mexico 2S&P Capital IQ Initiates Coverage on MabVax Therapeutics Holdings Inc. in S&P Capital IQ Factual Stock Reports 2S&P Capital IQ Initiates Coverage on MabVax Therapeutics Holdings Inc. in S&P Capital IQ Factual Stock Reports 3S&P Capital IQ Initiates Coverage on MabVax Therapeutics Holdings Inc. in S&P Capital IQ Factual Stock Reports 4S&P Capital IQ Initiates Coverage on MabVax Therapeutics Holdings Inc. in S&P Capital IQ Factual Stock Reports 523andMe Appoints Kate Black as Privacy Officer and Corporate Counsel 2
... AARUHS, Denmark, July 6 ... the EmbryoScope(TM) Embryo,Monitoring System and EmbryoSlide(TM) tray have ... use in IVF. Unisense Fertilitech A/S also received,the ... installation and servicing of IVF incubators and related,accessories. ...
... Mass., July 6 /PRNewswire-FirstCall/ -- Verenium Corporation (Nasdaq: ... amend the $29.5 million of outstanding 8% Senior Convertible Notes ... on July 1, 2009 is effective as of 8:00 a.m. ... Agreements with holders of 87% of the Notes, which is ...
... , REYKJAVIK, Iceland, July 6 Scientists at deCODE genetics ... and the United States today present in the journal ... for basal cell carcinoma (BCC) that affect people with fair ... single-letter variants in the sequence of the human genome (SNPs) ...
Cached Biology Technology:Unisense FertiliTech A/S Receives CE Mark of Approval for EmbryoScope(TM) Embryo Monitoring System 2Verenium Completes Amendment to 8% Senior Convertible Notes 2Verenium Completes Amendment to 8% Senior Convertible Notes 3Verenium Completes Amendment to 8% Senior Convertible Notes 4It's Not Just the Sun: deCODE Discovers Sequence Variants Affecting Susceptibility to Skin Cancer 2It's Not Just the Sun: deCODE Discovers Sequence Variants Affecting Susceptibility to Skin Cancer 3It's Not Just the Sun: deCODE Discovers Sequence Variants Affecting Susceptibility to Skin Cancer 4
... M-840 HEXALIGHT robot is based on PI's ... over more than a decade. PI Hexapods ... mirror and antenna adjustments over wide ranges ... six degrees of freedom with 3 m ...
... DNA sequencing is the experimental process of ... region. The automated DNA Sequencing is based ... DNA polymerase, which allows cycle sequencing reactions. ... detected in a capillary instrument controlled by ...
...
High-throughput DNA sequencing of any library. Just give us your transformation mixture, and we'll do the rest. ABI 3730xl's yield the longest read lengths available. LIMS tracking utilizing Geospiza...
Biology Products: