Navigation Links
Morphing DNA hydrogel flows like liquid but remembers its original shape
Date:12/5/2012

ITHACA, N.Y. A bit reminiscent of the Terminator T-1000, a new material created by Cornell researchers is so soft that it can flow like a liquid and then, strangely, return to its original shape.

Rather than liquid metal, it is a hydrogel, a mesh of organic molecules with many small empty spaces that can absorb water like a sponge. It qualifies as a "metamaterial" with properties not found in nature and may be the first organic metamaterial with mechanical meta-properties.

Hydrogels have already been considered for use in drug delivery the spaces can be filled with drugs that release slowly as the gel biodegrades and as frameworks for tissue rebuilding. The ability to form a gel into a desired shape further expands the possibilities. For example, a drug-infused gel could be formed to exactly fit the space inside a wound.

Dan Luo, professor of biological and environmental engineering, and colleagues describe their creation in the Dec. 2 issue of the journal Nature Nanotechnology.

The new hydrogel is made of synthetic DNA. In addition to being the stuff genes are made of, DNA can serve as a building block for self-assembling materials. Single strands of DNA will lock onto other single stands that have complementary coding, like tiny organic Legos. By synthesizing DNA with carefully arranged complementary sections Luo's research team previously created short stands that link into shapes such as crosses or Y's, which in turn join at the ends to form meshlike structures to form the first successful all-DNA hydrogel. Trying a new approach, they mixed synthetic DNA with enzymes that cause DNA to self-replicate and to extend itself into long chains, to make a hydrogel without DNA linkages.

"During this process they entangle, and the entanglement produces a 3-D network," Luo said. But the result was not what they expected: The hydrogel they made flows like a liquid, but when placed in water returns to the shape of t
'/>"/>

Contact: John Carberry
johncarberry@cornell.edu
607-255-5353
Cornell University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Debris flows, landslides, fossil microatolls, paleo-seasonality, and carbonate ore deposits
2. Faster, cheaper gas and liquid separation using custom designed and built mesoscopic structures
3. Liquid glucagon formulation discovered for potential use in artificial pancreas systems
4. Microbe that can handle ionic liquids
5. High-resolution atomic imaging of specimens in liquid by TEM using graphene liquid cell
6. Odorant shape and vibration likely lead to olfaction satisfaction
7. Oh, my stars and hexagons! DNA code shapes gold nanoparticles
8. Cells to Civilizations: The Principles of Change That Shape Life
9. Simple mathematcal pattern describes shape of neuron jungle
10. Not a 1-way street: Evolution shapes environment of Connecticut lakes
11. International team uncovers new genes that shape brain size, intelligence
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2014)... the seas during warm phases and became extinct during ... establishes a link between marine crocodilian diversity and the ... than 140 million years. , The research, led ... France and formerly from the University of Bristol, UK ... Today, crocodiles are ,cold-blooded, animals that mainly live in ...
(Date:8/19/2014)... at the University of Liverpool has found how worms ... with the body. , Dr Paolo Paoletti, alongside his ... mathematical model for earthworms and insect larvae which challenges ... get around. , The most widely accepted model is ... that the central brain of these creatures generates rhythmic ...
(Date:8/19/2014)... available in French . ... and RISKS of physical activity in children,Today the Canadian ... promotion of childhood physical activity and published their position ... and Metabolism ( APNM ). This position ... area of risk of physical activity for children and ...
Breaking Biology News(10 mins):Evolution of marine crocodilians constrained by ocean temperatures 2Secrets of how worms wriggle uncovered 2Taking a stand: Balancing the BENEFITS and RISKS of physical activity in children 2Taking a stand: Balancing the BENEFITS and RISKS of physical activity in children 3
... Scientists who have determined how much carbon is stored ... be used to accelerate global discussion about the strategy ... In an era of competing land use demands, the ... are abundant sources of other ecological goods and services ...
... College of Clinical Pharmacology (ACCP) has awarded ... director of Pediatric Clinical Pharmacology at Children,s National ... Dr. van den Anker, a neonatologist by training, ... contributions to pediatric clinical pharmacology," according to the ...
... 8, 2008-- The McClellan Nuclear Radiation Center (MNRC) in ... to detect corrosion and defects in aircraft structure using ... currently helping soil scientists understand the function of plant ... Scientists at the University of California in Davis present ...
Cached Biology News:Scientists point to forests for carbon storage solutions 2Scientists point to forests for carbon storage solutions 3Scientists point to forests for carbon storage solutions 4Scientists point to forests for carbon storage solutions 5US Air Force technology helps scientists understand plant root function 2
(Date:8/19/2014)... Research and Markets ... "Spectroscopy Equipment and Accessories - Global Strategic ... This report analyzes the ... in US$ Thousands by the following Product ... NMR-EPR Spectrometers, Near Infrared (NIR) Spectrometers, IR ...
(Date:8/19/2014)... , Aug. 19, 2014 /PRNewswire/ - iCo Therapeutics Inc. ... today reported results of its Oral Amphotericin B ... reservoirs.  The study, conducted by ImmuneCarta®, the immune ... vitro effectiveness of Oral Amp B in ... in individuals despite intensive treatment with antiretroviral therapy. ...
(Date:8/18/2014)... Diagnostics Inc. (TSX-V: SQD), a life sciences company that ... microarray diagnostics, today announced it will hold an investor ... ET.  During the call, Andrew ... SQI,s recent commercialization progress and then introduce Dr. ... to the Board of Directors of SQI and also ...
(Date:8/18/2014)... HIV Infection Drug Market and Pipeline Insight is a ... infection and the number of deaths due to AIDS has ... the globe. It has been estimated that the death rate ... with the rates for children being even much lower. A ... has been the improved access to antiretroviral drugs and therapy ...
Breaking Biology Technology:Global Spectroscopy Equipment and Accessories - Strategic Business Report 2014 2iCo Therapeutics Announces Positive Oral Amphotericin B Study Results 2iCo Therapeutics Announces Positive Oral Amphotericin B Study Results 3SQI Diagnostics Announces Investor Conference Call with Dr. Allan Pronovost 2SQI Diagnostics Announces Investor Conference Call with Dr. Allan Pronovost 3Global HIV Infection Drug Market Overview 2Global HIV Infection Drug Market Overview 3Global HIV Infection Drug Market Overview 4
... patient monitors and sensors, reported a net loss of $245,000 ... $6 million. , ,Sales were down from nearly $6.6 million ... also down, and the firm's net loss came down from ... at about $3.7 million. , ,Criticare (AMEX:CMD) said that several ...
... Now that spring is in gear, women looking for new ... a "shorts and tee shirts" alternative to the traditional conference ... until Sunday, with yoga in the mornings and two full ... of summer camp. ... Your physical surroundings and the things ...
... the Alzheimer's disease drug market in the United ... percent annually for the next five years. , ... Markets for Alzheimer's Disease Medications 2005," include Pfizer, ... Alzheimer's drug market that generated more than $1.3 ...
Cached Biology Technology:Women in technology confab comes to Wisconsin 2Alzheimer's drug market to hit $5.5 billion by 2009, study says 2
...
The Discovery Series PDQuest 2-D analysis software is used for imaging, analyzing, and databasing two-dimensional electrophoretic gels. The 10-user network license entitles ten users to access data f...
Mouse monoclonal antibody raised against a partial recombinant JRKL. NCBI Entrez Gene ID = JRKL...
Mouse monoclonal antibody to ST8SIA2 - ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2...
Biology Products: