Navigation Links
More than 1 way to be healthy: Map of bacterial makeup of humans reveals microbial rare biosphere

WOODS HOLE, MASS. The landmark publication this week of a "map" of the bacterial make-up of healthy humans has deep roots in an unexpected place: the ocean.

Microbial communities that live on and in the human body, known collectively as the microbiome, are thought to have a critical role in human health and disease. Five years ago, the National Institutes of Health launched the ambitious Human Microbiome Project (HMP) to define the boundaries of bacterial variation found in 242 healthy human beings.

"In order to understand what sick is, it's helpful to define the healthy microbiome first," says MBL scientist Susan M. Huse, lead author of one of the HMP reports published this week.

The project's 200 scientists from 80 institutions, including Huse and Mitchell Sogin from the MBL, faced the daunting task of making sense of more than 5,000 samples of human and bacterial DNA and 3.5 terabases of genomic data.

The solution? The HMP adopted several, state-of-the-art genetic sequencing and analysis methods, many of which were originally developed by the MBL for the International Census of Marine Microbesa massive, ten-year project that yielded the first inventory of microbial diversity in the world's oceans.

And, perhaps not surprisingly, the HMP discovered that microbial distributions in the human body are not so different from those in ocean ecosystems.

Whether in the human gut, mouth, or vagina, the Pacific Ocean or the Sargasso Sea, microbial communities contain a few highly abundant bacterial types plus many, many more low-abundance types (the so-called "rare biosphere," a phenomenon first discovered in ocean samples by Sogin and his MBL colleagues).

"The more closely we look, the more bacterial diversity we find," Huse says. "We can't even name all these kinds of bacteria we are discovering in human and environmental habitats. It's like trying to name all the stars." HMP researchers concluded t

Contact: Diana Kenney
Marine Biological Laboratory

Page: 1 2 3

Related biology news :

1. Bacterial shock to recapture essential phosphate
2. Researchers develop rapid test strips for bacterial contamination in swimming water
3. The activity of a bacterial effector protein seen in molecular detail
4. Copy of the genetic makeup travels in a protein suitcase
5. UC Santa Barbara researchers discover genetic link between visual pathways of hydras and humans
6. Bartonella infection associated with rheumatoid illnesses in humans
7. Research reveals first evidence of hunting by prehistoric Ohioans
8. Study reveals how monarch butterflies recolonize northern breeding range
9. Circadian rhythms have profound influence on metabolic output, UCI study reveals
10. Unexpected discovery reveals a new mechanism for how the cerebellum extracts signal from noise
11. Study by Haverford College professor reveals unprecedented impact of Deepwater Horizon on deep ocean
Post Your Comments:
Related Image:
More than 1 way to be healthy: Map of bacterial makeup of humans reveals microbial rare biosphere
(Date:8/27/2014)... Using functional near infrared spectroscopy (fNIRS), Kessler Foundation ... people with multiple sclerosis (MS) and healthy controls. ... brain activation was studied using fNIRS while participants ... cognition using functional near infrared spectroscopy (fNIRS) in ... by Brain Imaging and Behavior . Authors ...
(Date:8/27/2014)... easier when it only requires nerve cells to rearrange ... have to generate new patterns, a study of monkeys ... learn through recordings of electrical activity of brain cell ... Institutes of Health. , "We looked into the brain ... think outside the box," said Aaron Batista, Ph.D., an ...
(Date:8/27/2014)... to listen carefully to someone, the first thing we ... is stop moving altogether. This strategy helps us hear ... movements. , This interplay between movement and hearing also ... evidence has long suggested that the brain,s motor cortex, ... gives rise to our conscious perception of sound. , ...
Breaking Biology News(10 mins):Kessler Foundation researchers publish first study of brain activation in MS using fNIRS 2Scientists plug into a learning brain 2Scientists plug into a learning brain 3Stop and listen: Study shows how movement affects hearing 2Stop and listen: Study shows how movement affects hearing 3
... an important role in determining how much energy the ... hormone known as thyroid-stimulating hormone (TSH). Increased levels of ... for TSH, result in hyperthyroidism (characterized by weight loss ... burns) and goiter. Signals downstream of the receptor ...
... antioxidants, such as vitamins C and E, offer health-promoting benefits ... the August 10 issue of the journal Cell reveals that, ... mice that an overload of natural antioxidants can actually lead ... about the damaging effects of oxidative stress, but there is ...
... land-use policies in Peru have been key to tempering ... at the Carnegie Institutions Department of Global Ecology led ... satellite data covering most (79%) of the Peruvian Amazon ... August 9, 2007, on-line edition of Science Express. ...
Cached Biology News:Antioxidant overload may underlie a heritable human disease 2Rain forest protection works in Peru 2
(Date:8/27/2014)... , Aug. 27, 2014 ... the "Global Lactic Acid  (Biodegradable Polymer, Food ... Trends & Forecasts to 2019" report to ... simplest hydroxyl-carboxylic acid with an asymmetrical carbon atom. ... the biodegradable polymer, food and beverage, personal care ...
(Date:8/27/2014)... -- has added a new market research ... Rational View ... similar amount of hype currently surrounds graphene, with ... water treatment, but is graphene the only solution? ... Opportunity Report, authored by Tim Harper ...
(Date:8/27/2014)... Aug. 27, 2014 Tris Pharma, a specialty ... today announced that it has been selected as an ... Association,s 2014 Awards for Excellence competition in ... independent panel of judges from SCORE (Counselors to America,s ... will be honored at a gala event to be ...
(Date:8/27/2014)... College, PA (PRWEB) August 27, 2014 ... Simulation Software with new features for the biomedical ... is an enhanced Biological Thermal Sensor, exclusive to the ... a specialty version of XFdtd, developed to calculate the ... export functionality has been added to all versions to ...
Breaking Biology Technology:Global Lactic Acid (Biodegradable Polymer, Food & Beverage, Personal Care & Pharmaceutical) Market - Trends & Forecasts to 2019 2The Graphene Opportunity - A Rational View 2The Graphene Opportunity - A Rational View 3The Graphene Opportunity - A Rational View 4Tris Pharma Selected as an award winner in the New Jersey Business & Industry Association's 2014 Awards for Excellence 2Remcom Announces Enhanced Biological Thermal Sensor and Other Biomedical Features in XFdtd EM Simulation Software Update 2Remcom Announces Enhanced Biological Thermal Sensor and Other Biomedical Features in XFdtd EM Simulation Software Update 3
... LEXINGTON, Mass. and HEIDELBERG, Germany, July 13 ... the first human cancer biochip for HybSelect, febit,s highly automated technology ... cancer biochip features 115 important genes which are reported to be ... Institute. , , "Molecular signatures ...
... BOSTON, July 13 PAREXEL International Corporation (Nasdaq: ... on Monday, August 10, 2009 after the close of the stock market. ... on the PR Newswire website at , , ... 10:00 a.m. EDT on Tuesday, August 11, 2009 to discuss the results. ...
... (IL) today announced it will present the "Passion & ... for the International Society on Thrombosis and Haemostasis (ISTH) ... for Clinical Chemistry (AACC), held in Boston, MA on ... Launched in July 2008 as a part of ...
Cached Biology Technology:First Catalog Cancer Biochip for Sequence Capture Now Available from febit 2PAREXEL Announces Date of Fourth Quarter and Fiscal Year 2009 Earnings Release and Conference Call 2Instrumentation Laboratory to Announce 'Passion & Results' Award Winners 2Instrumentation Laboratory to Announce 'Passion & Results' Award Winners 3
Incomplete Adjuvant...
2,4-Dinitrophenyl hapten is conjugated to Human Serum Albumin (HSA) protein through lysine....
PGF1α-d4 contains 4 deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGF1α by GC- or LC-mass spectrometry....
PGD2-d4 contains 4 deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGD2 by GC- or LC-mass spectrometry....
Biology Products: