Navigation Links
More effective method of imaging proteins
Date:3/6/2012

Using a unique facility in the US, researchers at the University of Gothenburg have found a more effective way of imaging proteins. The next step is to film how proteins work at molecular level.

Mapping the structure of proteins and the work they do in cells could be the key to cures for everything from cancer to malaria. Last year Richard Neutze, professor of biochemistry at the University of Gothenburg, and his research group were among the first in the world to image proteins using very short and intensive X-ray pulses.

In a new study published in Nature Methods, the method has been tested on a new type of protein, with good results.

"To put it simply, we've developed a new method of creating incredibly small protein crystals," says Linda Johansson, doctoral student at the Department of Chemistry and Molecular Biology and lead author of the article. "We've also shown that it's possible to use very small crystals to determine a membrane protein structure."

Could become standard

There are two major challenges when it comes to imaging proteins: the first is to create the right sized protein crystals, and the second is to irradiate them in such a way that they do not disintegrate. Although Sweden has a facility for synchrotron-generated X-ray radiation Maxlab in Lund this type of technology is not sufficiently light-intensive and therefore requires large protein crystals which take several years to produce.

Richard Neutze was one of the researchers to float the idea that it might be possible to image small protein samples using free-electron lasers which emit intensive X-ray radiation in extremely short pulses shorter than the time it takes light to travel the width of a human hair. This kind of facility has been available in California since 2009, and it is this facility that was used for the study.

"Producing small protein crystals is easier and takes less time, so this method is muc
'/>"/>

Contact: Linda Johansson
linda.johansson@chem.gu.se
031-786-3244
University of Gothenburg
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
2. Commercial aquatic plants offer cost-effective method for treating wastewater
3. RNA molecules, delivery system improve vaccine responses, effectiveness
4. Cost-effective farm waste-to-energy technology focus of research
5. New Study Reveals the Emotional Impact and Effectiveness of Negative Campaigning
6. New study indicates smallpox vaccination effective for decades
7. Fractional dose of scarce meningitis vaccine may be effective in outbreak control
8. Flame retardants prove ineffective on fresh-cut Christmas trees
9. Flame retardants prove ineffective on fresh-cut Christmas trees
10. Organic plant waste proves effective weed control for citrus trees
11. Vidalia onions: Alternative to hand-transplanting proven effective
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
More effective method of imaging proteins
(Date:9/18/2014)... up to 400 kilometres in search of a home, which ... Clownfish spend their entire adult lives under the protection of ... open ocean, says study co-author, Dr Hugo Harrison from the ... at James Cook University. , "In the past we haven,t ... rare glimpse into how far they can swim, crossing large ...
(Date:9/17/2014)... care to reproductive technologies, the justice and well-being ... people to identify key issues, articulate their values ... the most defensible ways forward. But what are ... conversations?, The Hastings Center and the Presidential Commission ... up to publish a series of essays to ...
(Date:9/17/2014)... the Arts and Humanities has received a $260,000 grant ... project, "The Boundaries of the Human in the Age ... a wide-ranging series of events aimed at exploring two ... artists and researchers who are exploring the boundaries of ... humanism, and the other involves the increasingly influential hypothesis ...
Breaking Biology News(10 mins):Nemo's epic journey to find a new home 2Why bioethics literacy matters 2Why bioethics literacy matters 3Mellon Foundation awards grant for major project in the humanities and sciences 2
... April 22, 2012) Researchers at Columbia University Medical ... the retention and release of the brain,s stem cells. ... neurologic development and could eventually lead to regenerative therapies ... collaborative effort of the laboratories of Drs. Anna Lasorella ...
... reductions in salt content and taxation on products containing salt ... each year from cardiovascular disease (CVD) by 2-3 per cent ... World Congress of Cardiology are the first findings from a ... year. The study set out to assess ...
... the Florida campus of The Scripps Research Institute has been ... Health to develop a range of new tests that could ... degenerative disorders of advancing age. Shuji Kishi, an assistant ... three-year study. The new tests will focus on diseases ...
Cached Biology News:'Housekeeping' mechanism for brain stem cells discovered 2'Housekeeping' mechanism for brain stem cells discovered 3Tax on salt could reduce cardiovascular disease deaths by 3 percent 2Researcher awarded $1 million for stress-associated disease and aging research 2
(Date:9/18/2014)... YARDLEY , Pennsylvanie, 18 septembre 2014 ... Lyon en 1974, a été ... à compléter les évaluations cliniques traditionnelles par ... Reported Outcomes) et sur les impacts économiques ... http://photos.prnewswire.com/prnh/20140618/119365 A cours ...
(Date:9/18/2014)... can be pretty expensive. Now a team led by ... open-source library of designs that will let scientists slash ... the syringe pump. , Syringe pumps are used to ... or mixing chemicals in a reaction. They can also ... Pearce and his team of Michigan Tech students published ...
(Date:9/18/2014)... September 18, 2014 Silicon-valley Electronic Data ... Digitaliza TXT , the latest addition to Clinovo’s ... Clinical Research Organization (CRO) Program, Clinovo further expands its ... days of ClinCapture training, we are now able to ... Ana Pulido. “We can also rely on Clinovo to ...
(Date:9/17/2014)... FRANCISCO , Sept. 17, 2014 ... receiving accelerated partial breast irradiation (APBI) via interstitial ... those with positive lymph nodes could be suitable ... Radiation Oncology (ASTRO) guidelines place these patients in ... abstract at the 2014 ASTRO meeting, Beaumont Health ...
Breaking Biology Technology:1974 - 2014 - Mapi fête ses 40 ans 2Doing science just got cheaper -- and faster 2Digitaliza TXT Joins Clinovo’s CRO Partnership Program, Bringing Its Open Source EDC System, ClinCapture to Latin America 2Digitaliza TXT Joins Clinovo’s CRO Partnership Program, Bringing Its Open Source EDC System, ClinCapture to Latin America 3Partial Breast Irradiation With Interstitial Brachytherapy Appears Appropriate For Women Previously Considered Unsuitable 2Partial Breast Irradiation With Interstitial Brachytherapy Appears Appropriate For Women Previously Considered Unsuitable 3Partial Breast Irradiation With Interstitial Brachytherapy Appears Appropriate For Women Previously Considered Unsuitable 4
... Corporation,(Nasdaq: VOLC ) today announced that it will ... of fiscal 2007 on Tuesday, February 12., The ... financial,results and operating activities open to all interested parties ... Time), Tuesday, February,12, hosted by Scott Huennekens, president and ...
... Begin at ProHEALTH Facility by End of First Quarter, ... NBS ),which is pioneering the pre-disease collection, processing ... need, today announced,receipt of a provisional license for comprehensive ... from the New York State,Department of Health for the ...
... - Three New Board Members to Form Audit ... 5 /Xinhua-PRNewswire-FirstCall/ --,China Pharma Holdings, Inc. ("China Pharma") ... generic and brand,bio-pharmaceutical products in China, today announced ... Baowen Dong to its Board of Directors,forming the ...
Cached Biology Technology:Volcano Corporation Schedules Fourth Quarter Conference Call, Webcast 2NeoStem Announces NY State License for Adult Stem Cell Collection 2NeoStem Announces NY State License for Adult Stem Cell Collection 3China Pharma Appoints Three Independent Non-Executive Directors 2China Pharma Appoints Three Independent Non-Executive Directors 3
Rabbit polyclonal to Leucyl tRNA synthetase ( Abpromise for all tested applications). Antigen: L930-H1176 denatured human recombinant LRS. Entrez Gene ID: 3926 Swiss Protein ID: Q9P2J5...
Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2). [Source:Uniprot/SWISSPROT;Acc:P19878] Antigen: Recombinant Protein E...
... Rabbit polyclonal to FANCM ( Abpromise ... Antigen: Synthetic peptide derived from ... Human FANCM. (Note: the amino acid ... available as ab27787 .) ...
Rabbit polyclonal to 13,14 dihydro 15 keto Prostaglandin E2 ( Abpromise for all tested applications)....
Biology Products: