Navigation Links
More effective kidney stone treatment, from the macroscopic to the nanoscale
Date:4/17/2014

Researchers in France have hit on a novel method to help kidney stone sufferers ensure they receive the correct and most effective treatment possible.

Kidney stones represent a major medical problem in the western and developing world. If left untreated, apart from being particularly painful, they can lead to renal failure and other complications. In many patients treated successfully, stone recurrence is also amajor problem. Clearly a more effective pathological approach to diagnosis and treatment needs to be identified to ensure successful eradication of stones.

Worldwide approximately 1:7000 births are affected by cystinuria, the most frequent cause of stone formation among genetic diseases. Whilst stones are treatable many therapies exist with varying results depending on the type of stone and severity of the incidence.

Cystine stones, of which there are two forms, are composed of tiny micrometre-size crystallites, which are made up of a collection of nanocrystals. Both forms of cystine stone behave in a particular way under different chemical conditions induced by the drug or drugs administered.

By crystallographic techniques Dominique Bazin, Director of Research at Universit Paris-Sud 11, France (now at LCMCP-College de France), and co-workers [J. Appl. Cryst. (2014). 47, 719-725; doi:10.1107/S1600576714004658] were able to understand how some of the methods employed to medically treat the stones have different effects on the stone, from reducing the size of both nanocrystals and crystallites to changing the shape and space occupied by the crystallites at the macroscale.

Clear evidence is now available to help doctors diagnose and prescribe the correct drugs for patients with kidney stones more successfully. Trials did indicate, however, that a lot of the success that can be seen in recovery rates and non-recurrence does depend on the patient also complying with the drug regime prescribed.


'/>"/>

Contact: Dr. Jonathan Agbenyega
ja@iucr.org
44-124-434-2878
International Union of Crystallography
Source:Eurekalert  

Page: 1

Related biology news :

1. Enzyme wrench could be key to stronger, more effective antibiotics
2. Friedreichs ataxia -- an effective gene therapy in an animal model
3. Ordinary conditioner removes head lice eggs as effectively as special products
4. Engineered virus is effective against triple negative breast cancer cells
5. Effective control of invasive weeds can help attempts at reforestation in Panama
6. An improved, cost-effective catalyst for water-splitting devices
7. Study finds Catalina Island Conservancy contraception program effectively manages bison population
8. Researchers engineer a hybrid 5 times more effective in delivering genetic material into cells
9. Study finds piece-by-piece approach to emissions policies can be effective
10. Researchers develop system for assessing how effective species are at pollinating crops
11. Oxygen levels increase and decrease the effectiveness of anti-inflammatory therapies
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
More effective kidney stone treatment, from the macroscopic to the nanoscale
(Date:3/22/2016)... PUNE, India , March 22, 2016 ... new market research report "Electronic Sensors Market for ... Fingerprint, Proximity, & Others), Application (Communication & ... and Geography - Global Forecast to 2022", ... consumer industry is expected to reach USD ...
(Date:3/21/2016)... , March 22, 2016 ... recognition with passcodes for superior security   ... a leading provider of secure digital communications services, today ... biometric technology and offer enterprise customers, particularly those in ... facial recognition and voice authentication within a mobile app, ...
(Date:3/17/2016)... -- ABI Research, the leader in transformative technology ... will reach more than $30 billion by 2021, ... electronics, particularly smartphones, continue to boost the biometrics ... two billion shipments by 2021 at a 40% ... Analyst at ABI Research. "Surveillance is also gearing ...
Breaking Biology News(10 mins):
(Date:4/27/2016)... (PRWEB) , ... April 27, 2016 , ... ... of cannabis testing technology at the Spring 2016 Marijuana Business Conference and Expo. ... pesticides, residual solvents, heavy metals, and more. Expo attendees can stop by booth ...
(Date:4/27/2016)... ... April 27, 2016 , ... Most consumers engage ... fingerprint recognition for secure access, voice recognition for hands-free communication, and facial recognition ... interacting with biometrics technology today. But if they asked Joey Pritikin, Vice ...
(Date:4/27/2016)... and RESEARCH TRIANGLE PARK, N.C. ... (NASDAQ: UTHR ) announced today that ... of United Therapeutics will provide an overview and update ... st Annual Health Care Conference. The ... at 10:00 a.m. Eastern Time, and can be accessed ...
(Date:4/27/2016)... ... 2016 , ... NDA Partners Chairman Carl Peck, MD ... Consultant. Mr. Clark was formerly a Vice President with US Pharmacopeia, where ... monographs based on analytical methods. NDA Partners Expert Consultants are top tier ...
Breaking Biology Technology: