Navigation Links
Montreal Heart Institute and Mount Sinai Hospital researchers contribute to Crohn's disease study
Date:6/30/2008

ed the 11 previously identified genetic risk factors, but it also identified 21 new ones. These new discoveries continue to build a picture of factors leading to the inappropriate immune-system activation that characterizes the disorder.

"Given the fact that prior to 2007 we only knew of three genetic risk factors for Crohn's disease truly represents tremendous progress in our ability to understand Crohn's disease. Specifically this study is indicating which biological pathways specifically lead to Crohn's disease as well as which of these pathways are in common with other immune mediated diseases such as autoimmune diabetes, lupus and rheumatoid arthritis," says Dr. Rioux, co-author of the current study.

"This is breakthrough research for patients with Crohn's disease and one of the most significant advances in our understanding of this disease, to date," says Dr. Silverberg, co-author of the study.

"Our research was successful because of the international collaborative approach."

Finally, Rioux stated that "the hope is that the identification of the biological paths that lead to Crohn's disease can be translated into useful clinical tools for improved diagnosis, classification and treatment of this chronic disease."

In total, the effort constituted a collaboration between clinical genetic researchers from 25 institutions across North America including Yale University, University of Pittsburgh, Universit de Montral, University of Toronto, Johns Hopkins University, and Cedars-Sinai Medical Center in Los Angeles the United Kingdom, Belgium and France. The team is committed to further advancing these results in collaboration with investigators from additional countries. Support for the study came from several organizations, including the National Institute of Diabetes and Digestive and Kidney Diseases, through the Inflammatory Bowel Disease Genetic Consortium.


'/>"/>

Contact: Doris Prince
doris.prince@icm-mhi.org
514-376-3330
University of Montreal
Source:Eurekalert

Page: 1 2

Related biology news :

1. NASA keeps eye on ozone layer amid Montreal Protocols success
2. Abnormal fat metabolism underlies heart problems in diabetic patients
3. High blood pressure, low energy -- a recipe for heart failure
4. Human derived stem cells can repair rat hearts damaged by heart attack
5. Geron Demonstrates hESC-derived cardiomyocytes improve heart function after myocardial infarction
6. Heart of Herschel to be presented to media
7. Minimally invasive heart surgery research wins NIH award
8. A step toward tissue-engineered heart structures for children
9. Research explains link between cholesterol and heart disease
10. Eating competence may lower risk of heart disease
11. Cardiologists and heart surgeons meet for Controversies and Advances conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... Miranda, a small, icy moon of Uranus, is one ... the solar system. Despite its relatively small size, Miranda ... that resulted in the formation of at least three ... coronae. , These coronae are visible in Miranda,s ... km across. Arden corona, the largest, has ridges and ...
(Date:9/18/2014)... many times it,s demonstrated, it,s still hard to ... But by using a signaling system called "quorum ... to suit their population. In short, some bacteria ... act accordingly. , Once the population of quorum-sensing ... innocuous to pathogenic, or from unhelpful to helpful. ...
(Date:9/18/2014)... 18, 2014 -- Arizona turned its newborn screening program into ... short months, earning it the first-ever Newborn Screening Quality Award ... Dimes presented Will Humble, M.P.H., Arizona,s Department of Health Services ... Mr. Humble established a policy of full transparency for the ... blood samples to the lab for analysis, and set a ...
Breaking Biology News(10 mins):Miranda: An icy moon deformed by tidal heating 2Miranda: An icy moon deformed by tidal heating 3Miranda: An icy moon deformed by tidal heating 4Miranda: An icy moon deformed by tidal heating 5Miranda: An icy moon deformed by tidal heating 6Miranda: An icy moon deformed by tidal heating 7Researchers study vital 'on/off switches' that control when bacteria turn deadly 2Researchers study vital 'on/off switches' that control when bacteria turn deadly 3March of Dimes honors Arizona with first-ever newborn screening award 2March of Dimes honors Arizona with first-ever newborn screening award 3
... Move over Longface, Spooktacular and Trickster - theres ... Bulldog, a new variety of the familiar fall fruit ... pumpkin growers. Researchers at the University of Georgia recently ... fall and Halloween displays. Dr. Gerard Krewer from ...
... release is available in French . , ... researchers has completed a massive survey of the network ... life. In the online edition of the journal Science, ... and networks of complexes never before observed including ...
... NY, May 13, 2008Gene therapy to replace the faulty CLN2 ... age 8-12 years, was able to slow significantly the rate ... published online ahead of print in the May 2008 issue ... journal published by Mary Ann Liebert, Inc. The paper is ...
Cached Biology News:Researchers discover architecture for fundamental processes of life 2Gene therapy slows progression of fatal neurodegenerative disease in children 2
(Date:9/18/2014)... Washington, USA (PRWEB) September 18, 2014 ... Representatives of a bill designed to stimulate development and ... jobs is being praised by leaders of SPIE, ... bill, the Revitalizing American Manufacturing and Innovation (RAMI) Act, ... The bill’s authors have said they are optimistic that ...
(Date:9/18/2014)... 2014  Health Enhancement Products, Inc. (OTCQB: HEPI), a ... compounds and metabolic processes, is pleased to announce the addition ... Ms. Nola E. Masterson , a California ... effective September 17, 2014. "We,re very pleased ... board," states Andrew Dahl , President and CEO. "She ...
(Date:9/18/2014)... , Sept. 18, 2014 ... of the "Global N-acetylcysteine Industry Report 2014" ... The Global N-acetylcysteine Industry Report 2014 is a ... of the global N-acetylcysteine industry. The ... including definitions, classifications, applications and industry chain structure. ...
(Date:9/18/2014)... -- MEI Pharma, Inc. (Nasdaq: MEIP ), an oncology ... cancer, announced today that Daniel P. Gold , Ph.D., ... NewsMakers in the Biotech Industry conference on Friday, September ... Broadway Hotel & Conference Center in New York ... accessed at www.meipharma.com . A replay will be available ...
Breaking Biology Technology:House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 2House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 3Health Enhancement Announces New Board Member In Advance Of Annual Shareholder Meeting 2Global N-acetylcysteine Industry Report 2014 2MEI Pharma To Present At BioCentury's NewsMakers Conference 2MEI Pharma To Present At BioCentury's NewsMakers Conference 3
... SUPG ), a pharmaceutical company dedicated to the discovery, ... malignancies, invites all interested parties to listen and,view a ... at 9:30 a.m. ET,(6:30 a.m. PT) to approximately 12:00 ... Investors and interested parties may access the webcast ...
... RICHMOND, Va., April 22 Insmed Inc. (Nasdaq:,INSM), ... today that Geoffrey Allan, Ph.D., CEO of Insmed, ... conference on FOBs, on April 29,2008 at 2:15 ... conference, entitled "Evaluate the Legislative, Economic and,Scientific Implications ...
... PARK, Ill. and ST. PAUL, Minn., ... will promote and distribute Abbott,s FreeStyle,Navigator ... Smiths Medical MD is the manufacturer,of ... ) and the Deltec Cozmo,insulin pump., ...
Cached Biology Technology:Insmed to Present at CBI Follow-On Biologics Conference 2Insmed to Present at CBI Follow-On Biologics Conference 3Smiths Medical to Promote and Distribute Abbott's FreeStyle Navigator Continuous Glucose Monitoring System 2Smiths Medical to Promote and Distribute Abbott's FreeStyle Navigator Continuous Glucose Monitoring System 3Smiths Medical to Promote and Distribute Abbott's FreeStyle Navigator Continuous Glucose Monitoring System 4
EZ-DeWax is a one-step solution that simultanously removes paraffin from and rehydrates formalin-fixed, paraffin embedded tissue...
Artisan™ Wash Solution (x 50) Additional Information: EU regulatory status: CE US regulatory status: IVD ...
... is an inexpensive personal or mini thermal cycler, ... Lightweight, with a small footprint, it can be ... researcher's desk. , The Gene Cycler thermal cycler ... have access to a large laboratory thermal cycler, ...
... Secondary Detection System is intended for use ... Antibody reagents, which contain rat and goat ... by light microscopy in paraffin-embedded tissues. The ... also be used with other rat or ...
Biology Products: